English
Related papers

Related papers: GRIM-filter: fast seed filtering in read mapping u…

200 papers

This paper discusses recent research that aims to enable computation close to data, an approach we broadly call processing-in-memory (PIM). PIM places computation mechanisms in or near where the data is stored (i.e., inside memory chips or…

Hardware Architecture · Computer Science 2025-02-07 Onur Mutlu , Saugata Ghose , Juan Gómez-Luna , Rachata Ausavarungnirun , Mohammad Sadrosadati , Geraldo F. Oliveira

Designing protein sequences that fold into a target 3-D structure, termed as the inverse folding problem, is central to protein engineering. However, it remains challenging due to the vast sequence space and the importance of local…

Quantitative Methods · Quantitative Biology 2026-03-17 Sazan Mahbub , Souvik Kundu , Eric P. Xing

Matching local features across images is a fundamental problem in computer vision. Targeting towards high accuracy and efficiency, we propose Seeded Graph Matching Network, a graph neural network with sparse structure to reduce redundant…

Computer Vision and Pattern Recognition · Computer Science 2021-08-20 Hongkai Chen , Zixin Luo , Jiahui Zhang , Lei Zhou , Xuyang Bai , Zeyu Hu , Chiew-Lan Tai , Long Quan

Real-life medical data is often multimodal and incomplete, fueling the growing need for advanced deep learning models capable of integrating them efficiently. The use of diverse modalities, including histopathology slides, MRI, and genetic…

Artificial Intelligence · Computer Science 2024-10-02 Lucas Robinet , Ahmad Berjaoui , Ziad Kheil , Elizabeth Cohen-Jonathan Moyal

We explored an uncharted part of the solution space for sorting algorithms: the role of symmetry in divide&conquer algorithms. We found/designed novel simple binary Quicksort and Mergesort algorithms operating in contiguous space which…

Data Structures and Algorithms · Computer Science 2024-02-06 Jens Oehlschlägel

There are currently plenty of programs available for mapping short sequences (reads) to a genome. Most of them, however, including such popular and actively developed programs as Bowtie, BWA, TopHat and many others, are based on…

Genomics · Quantitative Biology 2019-08-06 Igor Seledtsov , Jaroslav Efremov , Vladimir Molodtsov , Victor Solovyev

Motivation: Read mapping is a computationally expensive process and a major bottleneck in genomics analyses. The performance of read mapping is mainly limited by the performance of three key computational steps: Index Querying, Seed…

Hardware Architecture · Computer Science 2023-10-02 Julien Eudine , Mohammed Alser , Gagandeep Singh , Can Alkan , Onur Mutlu

Image matching, which establishes correspondences between two-view images to recover 3D structure and camera geometry, serves as a cornerstone in computer vision and underpins a wide range of applications, including visual localization, 3D…

Computer Vision and Pattern Recognition · Computer Science 2025-06-06 Shihua Zhang , Zizhuo Li , Kaining Zhang , Yifan Lu , Yuxin Deng , Linfeng Tang , Xingyu Jiang , Jiayi Ma

Searching for similar genomic sequences is an essential and fundamental step in biomedical research and an overwhelming majority of genomic analyses. State-of-the-art computational methods performing such comparisons fail to cope with the…

Data Structures and Algorithms · Computer Science 2024-07-11 Mohammed Alser , Julien Eudine , Onur Mutlu

Deep generative models can learn to generate realistic-looking images, but many of the most effective methods are adversarial and involve a saddlepoint optimization, which requires a careful balancing of training between a generator network…

Machine Learning · Statistics 2020-02-18 Akash Srivastava , Kai Xu , Michael U. Gutmann , Charles Sutton

A critical need has emerged for generative AI: attribution methods. That is, solutions that can identify the model originating AI-generated content. This feature, generally relevant in multimodal applications, is especially sensitive in…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Emanuele Ricco , Elia Onofri , Lorenzo Cima , Stefano Cresci , Roberto Di Pietro

Reducing the cost of sequencing genomes provided by next-generation sequencing technologies has greatly increased the number of genomic projects. As a result, there is a growing need for better assembly and assembly validation methods. One…

Genomics · Quantitative Biology 2022-10-17 Przemysław Stawczyk , Robert Nowak

High read depth can be used to assemble short sequence repeats. The existing genome assemblers fail in repetitive regions of longer than average read. I propose a new algorithm for a DNA assembly which uses the relative frequency of reads…

Genomics · Quantitative Biology 2015-01-08 Robert M. Nowak

Decision trees are one of the most popular classifiers in the machine learning literature. While the most common decision tree learning algorithms treat data as a batch, numerous algorithms have been proposed to construct decision trees…

Machine Learning · Computer Science 2026-01-21 Nikolaj Tatti

In image-based camera localization systems, information about the environment is usually stored in some representation, which can be referred to as a map. Conventionally, most maps are built upon hand-crafted features. Recently, neural…

Computer Vision and Pattern Recognition · Computer Science 2019-04-17 Mingpan Guo , Stefan Matthes , Jiaojiao Ye , Hao Shen

Traditional sparse and dense retrieval methods struggle to leverage general world knowledge and often fail to capture the nuanced features of queries and products. With the advent of large language models (LLMs), industrial search systems…

Information Retrieval · Computer Science 2025-07-14 Ming Pang , Chunyuan Yuan , Xiaoyu He , Zheng Fang , Donghao Xie , Fanyi Qu , Xue Jiang , Changping Peng , Zhangang Lin , Ching Law , Jingping Shao

In this paper, we propose a semi-supervised deep learning method for detecting the specific types of reads that impede the de novo genome assembly process. Instead of dealing directly with sequenced reads, we analyze their coverage graphs…

Machine Learning · Computer Science 2019-04-24 Tomislav Šebrek , Jan Tomljanović , Josip Krapac , Mile Šikić

Genome analysis fundamentally starts with a process known as read mapping, where sequenced fragments of an organism's genome are compared against a reference genome. Read mapping is currently a major bottleneck in the entire genome analysis…

Hardware Architecture · Computer Science 2020-10-29 Mohammed Alser , Zülal Bingöl , Damla Senol Cali , Jeremie Kim , Saugata Ghose , Can Alkan , Onur Mutlu

Architectures that incorporate Computing-in-Memory (CiM) using emerging non-volatile memory (NVM) devices have become strong contenders for deep neural network (DNN) acceleration due to their impressive energy efficiency. Yet, a significant…

Hardware Architecture · Computer Science 2024-01-12 Zheyu Yan , Xiaobo Sharon Hu , Yiyu Shi

Selecting data points for model training is critical in machine learning. Effective selection methods can reduce the labeling effort, optimize on-device training for embedded systems with limited data storage, and enhance the model…

Machine Learning · Computer Science 2025-05-23 Marcus Rüb , Daniel Konegen , Patrick Selle , Axel Sikora , Daniel Mueller-Gritschneder