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Pairwise alignment of DNA sequencing data is a ubiquitous task in bioinformatics and typically represents a heavy computational burden. State-of-the-art approaches to speed up this task use hashing to identify short segments (k-mers) that…

Machine Learning · Computer Science 2021-02-16 Govinda M. Kamath , Tavor Z. Baharav , Ilan Shomorony

Cheap high-throughput DNA sequencing may soon become routine not only for human genomes but also for practically anything requiring the identification of living organisms from their DNA: tracking of infectious agents, control of food…

Genomics · Quantitative Biology 2014-03-05 Laurent Gautier , Ole Lund

Local binary descriptors are attracting increasingly attention due to their great advantages in computational speed, which are able to achieve real-time performance in numerous image/vision applications. Various methods have been proposed…

Computer Vision and Pattern Recognition · Computer Science 2015-10-28 Yongqiang Gao , Weilin Huang , Yu Qiao

Recent advances in high-throughput cDNA sequencing (RNA-Seq) technology have revolutionized transcriptome studies. A major motivation for RNA-Seq is to map the structure of expressed transcripts at nucleotide resolution. With accurate…

Genomics · Quantitative Biology 2013-09-23 Georg Zeller , Nico Goernitz , Andre Kahles , Jonas Behr , Pramod Mudrakarta , Soeren Sonnenburg , Gunnar Raetsch

Recent recommender systems started to use rating elicitation, which asks new users to rate a small seed itemset for inferring their preferences, to improve the quality of initial recommendations. The key challenge of the rating elicitation…

Information Retrieval · Computer Science 2024-02-27 Wonbin Kweon , SeongKu Kang , Junyoung Hwang , Hwanjo Yu

The Distributed Bloom Filter is a space-efficient, probabilistic data structure designed to perform more efficient set reconciliations in distributed systems. It guarantees eventual consistency of states between nodes in a system, while…

Data Structures and Algorithms · Computer Science 2020-02-20 Lum Ramabaja , Arber Avdullahu

There is a growing interest in designing Graph Neural Networks (GNNs) for seeded graph matching, which aims to match two unlabeled graphs using only topological information and a small set of seed nodes. However, most previous GNNs for this…

Machine Learning · Computer Science 2023-07-11 Liren Yu , Jiaming Xu , Xiaojun Lin

Gene annotation has traditionally required direct comparison of DNA sequences between an unknown gene and a database of known ones using string comparison methods. However, these methods do not provide useful information when a gene does…

Machine Learning · Computer Science 2019-09-17 James K. Senter , Taylor M. Royalty , Andrew D. Steen , Amir Sadovnik

Random reshuffling, which randomly permutes the dataset each epoch, is widely adopted in model training because it yields faster convergence than with-replacement sampling. Recent studies indicate greedily chosen data orderings can further…

Machine Learning · Computer Science 2023-01-05 Yucheng Lu , Wentao Guo , Christopher De Sa

In the past several years, the problem of genome assembly has received considerable attention from both biologists and computer scientists. An important component of current assembly methods is the scaffolding process. This process involves…

Genomics · Quantitative Biology 2013-07-03 Karl R. B. Schmitt , Aleksey V. Zimin , Guillaume Marcaçs , James A. Yorke , Michelle Girvan

The selection problem, where one wishes to locate the $k^{th}$ smallest element in an unsorted array of size $n$, is one of the basic problems studied in computer science. The main focus of this work is designing algorithms for solving the…

Data Structures and Algorithms · Computer Science 2012-08-30 Tsvi Kopelowitz , Nimrod Talmon

We present a parallel algorithm and scalable implementation for genome analysis, specifically the problem of finding overlaps and alignments for data from "third generation" long read sequencers. While long sequences of DNA offer enormous…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-01-29 Marquita Ellis , Giulia Guidi , Aydın Buluç , Leonid Oliker , Katherine Yelick

DNA read mapping is a computationally expensive bioinformatics task, required for genome assembly and consensus polishing. It requires to find the best-fitting location for each DNA read on a long reference sequence. A novel resistive…

Genomics · Quantitative Biology 2019-01-29 Roman Kaplan , Leonid Yavits , Ran Ginosar

Recent advances in 3D Gaussian diffusion models suffer from time-intensive denoising and post-denoising processing due to the massive number of Gaussian primitives, resulting in slow generation and limited scalability along sampling…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 Zeyuan Yin , Xiaoming Liu

Pretrained vision-language models such as CLIP exhibit strong zero-shot generalization but remain sensitive to distribution shifts. Test-time adaptation adapts models during inference without access to source data or target labels, offering…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Wenxuan Bao , Yanjun Zhao , Xiyuan Yang , Jingrui He

The continually increasing volume of DNA sequence data has resulted in a growing demand for fast implementations of core algorithms. Computation of pairwise alignments between candidate haplotypes and sequencing reads using Pair-HMMs is a…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-27 Bertil Schmidt , Felix Kallenborn , Alexander Wichmann , Alejandro Chacon , Christian Hundt

We introduce marginalization models (MAMs), a new family of generative models for high-dimensional discrete data. They offer scalable and flexible generative modeling by explicitly modeling all induced marginal distributions.…

Machine Learning · Computer Science 2024-10-08 Sulin Liu , Peter J. Ramadge , Ryan P. Adams

Lidar SLAM plays a significant role in mobile robot navigation and high-definition map construction. However, existing methods often face a trade-off between localization accuracy and system robustness in scenarios with a high proportion of…

Robotics · Computer Science 2025-12-02 Yongxin Shao , Aihong Tan , Binrui Wang , Yinlian Jin , Licong Guan , Peng Liao

Genome sequence analysis plays a pivotal role in enabling many medical and scientific advancements in personalized medicine, outbreak tracing, and forensics. However, the analysis of genome sequencing data is currently bottlenecked by the…

Hardware Architecture · Computer Science 2021-11-04 Damla Senol Cali

The alignment of two similar graphs from different domains is a well-studied problem. In many practical usages, there is no reliable information or labels over the vertices or edges, leaving structural similarity as the only information…

Social and Information Networks · Computer Science 2022-08-22 Barak Babayov , Yoram Louzoun
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