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General-purpose LLMs are increasingly functioning as mental health infrastructure due to gaps in care left by provider shortages, inadequate insurance coverage, social isolation, and stigma around formal help-seeking. This shift poses a…

Computers and Society · Computer Science 2026-05-25 Briana Vecchione , Meryl Ye , Livia Garofalo , Ranjit Singh

Mental health disorders are particularly prevalent among those in the criminal justice system and may be a contributing factor in recidivism. Using North Carolina court cases from 1994 to 2009, this paper evaluates how mandated mental…

General Economics · Economics 2023-11-15 Rachel Nesbit

Uncontrolled hypertension is a global problem that needs to be addressed. Despite the many mHealth solutions in the market, the nonadherence relative to intended use jeopardizes treatment success. Although investigating user experience is…

Human-Computer Interaction · Computer Science 2023-11-10 Danielly de Paula , Ariane Sasso , Justus Coester , Erwin Boettinger

Falls are common in people with Parkinson's disease (PD) and have detrimental effects which can lower the quality of life. While studies have been conducted to learn about falling in general, factors distinguishing injurious from…

Applications · Statistics 2019-10-08 Sarini Abdullah , James McGree , Nicole White , Kerrie Mengersen , Graham Kerr

The health outcomes of high-need patients can be substantially influenced by the degree of patient engagement in their own care. The role of care managers includes that of enrolling patients into care programs and keeping them sufficiently…

Machine Learning · Computer Science 2019-06-21 Subhro Das , Chandramouli Maduri , Ching-Hua Chen , Pei-Yun S. Hsueh

More than 60% of individuals recovering from substance use disorder relapse within one year. Some will resume drug consumption even after decades of abstinence. The cognitive and psychological mechanisms that lead to relapse are not…

Quantitative Methods · Quantitative Biology 2026-05-12 Sayun Mao , Tom Chou , Maria D'Orsogna

Randomized experiments can be susceptible to selection bias due to potential non-compliance by the participants. While much of the existing work has studied compliance as a static behavior, we propose a game-theoretic model to study…

Machine Learning · Computer Science 2021-07-29 Daniel Ngo , Logan Stapleton , Vasilis Syrgkanis , Zhiwei Steven Wu

The dearth of prescribing guidelines for physicians is one key driver of the current opioid epidemic in the United States. In this work, we analyze medical and pharmaceutical claims data to draw insights on characteristics of patients who…

Machine Learning · Computer Science 2020-05-01 Chirag Nagpal , Dennis Wei , Bhanukiran Vinzamuri , Monica Shekhar , Sara E. Berger , Subhro Das , Kush R. Varshney

In consequential domains, it is often impossible to compel individuals to take treatment, so that optimal policy rules are merely suggestions in the presence of human non-adherence to treatment recommendations. We study personalized…

Machine Learning · Computer Science 2026-04-24 Angela Zhou

Artificial intelligence (AI) systems are increasingly integrated into healthcare and pharmacy workflows, supporting tasks such as medication recommendations, dosage determination, and drug interaction detection. While these systems often…

Artificial Intelligence · Computer Science 2026-05-21 Khalid Adnan Alsayed

HIV dynamic studies have contributed significantly to the understanding of HIV pathogenesis and antiviral treatment strategies for AIDS patients. Establishing the relationship of virologic responses with clinical factors and covariates…

Applications · Statistics 2011-04-19 Yangxin Huang , Hulin Wu , Jeanne Holden-Wiltse , Edward P. Acosta

Objective To assess the price elasticity of branded imatinib in chronic myeloid leukemia (CML) patients on Medicare Part D to determine if high out-of-pocket payments (OOP) are driving the substantial levels of non-adherence observed in…

Econometrics · Economics 2023-05-11 Samantha E. Clark , Ruth Etzioni , Jerry Radich , Zachary Marcum , Anirban Basu

Many drugs used therapeutically or recreationally induce tolerance: the effect of the substance decreases with repeated use. This phenomenon may reduce the efficacy of the substance unless dosage is increased beyond what is healthy for the…

Dynamical Systems · Mathematics 2024-03-19 Golrokh Nouri , Paul Tupper

Managing patients with multimorbidity often results in polypharmacy: the prescription of multiple drugs. However, the long-term effects of specific combinations of drugs and diseases are typically unknown. In particular, drugs prescribed…

Artificial Intelligence · Computer Science 2016-12-12 Jessa Bekker , Arjen Hommersom , Martijn Lappenschaar , Jesse Davis

Health artificial intelligence (AI) adoption presents a paradox: point-solution tools diffuse readily through clinical populations, yet system-change AI, which carries the greatest potential for pathway-level transformation, consistently…

Theoretical Economics · Economics 2026-05-19 Ari Ercole

This study proposes a method to identify treatment effects without exclusion restrictions in randomized experiments with noncompliance. Exploiting a baseline survey commonly available in randomized experiments, I decompose the…

General Economics · Economics 2021-06-03 Masayuki Sawada

Increasing evidence has shown that theory-based health behavior change interventions are more effective than non-theory-based ones. However, only a few segments of relevant studies were theory-based, especially the studies conducted by…

Human-Computer Interaction · Computer Science 2017-12-08 Yunlong Wang , Ahmed Fadhil , Jan-Philipp Lange , Harald Reiterer

As countries interact more and more, technology gains a decisive role in facilitating today's increased need for interconnection. At the same time, systems, becoming more advanced as technology progresses, feed each other and can produce…

Systems and Control · Electrical Eng. & Systems 2021-12-14 Evripidis P. Kechagias , Dimitrios M. Miloulis , Georgios Chatzistelios , Sotiris P. Gayialis , Georgios A. Papadopoulos

The rise in popularity of physical activity trackers provides extensive opportunities for research on personal health, however, barriers such as compliance attrition can lead to substantial losses in data. As such, insights into student's…

Human-Computer Interaction · Computer Science 2018-04-13 Louis Faust , Priscilla Jiménez , David Hachen , Omar Lizardo , Aaron Striegel , Nitesh V. Chawla

Clinical machine learning applications are often plagued with confounders that can impact the generalizability and predictive performance of the learners. Confounding is especially problematic in remote digital health studies where the…

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