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We study causal inference in randomized experiments (or quasi-experiments) following a $2\times 2$ factorial design. There are two treatments, denoted $A$ and $B$, and units are randomly assigned to one of four categories: treatment $A$…

Econometrics · Economics 2024-12-12 Mate Kormos , Robert P. Lieli , Martin Huber

Causal inference and model interpretability research are gaining increasing attention, especially in the domains of healthcare and bioinformatics. Despite recent successes in this field, decorrelating features under nonlinear environments…

Machine Learning · Computer Science 2022-09-30 Junda Wang , Weijian Li , Han Wang , Hanjia Lyu , Caroline Thirukumaran , Addisu Mesfin , Jiebo Luo

Memory-based medication non-adherence is an unsolved problem that is responsible for considerable disease burden in the United States. Digital medication intake reminder solutions with minimal onboarding requirements that are usable at the…

Information Retrieval · Computer Science 2023-12-13 Eden Shaveet , Utkarsh Singh , Nicholas Assaderaghi , Maximo Librandi

The rapid increase in the world's aging population to 16% by the year 2050 spurs the need for the application of digital health solutions to enhance older individuals' independence, accessibility, and well-being. While digital health…

Computers and Society · Computer Science 2026-01-27 Christine Ine

The well-being of older adults relies significantly on maintaining balance and mobility. As physical ability declines, older adults often accept the need for assistive devices. However, existing walkers frequently fail to consider user…

Computers and Society · Computer Science 2025-04-28 Victory A. Aruona , Sergio D. Sierra M. , Nigel Harris , Marcela Munera , Carlos A. Cifuentes

When studying human-technology interaction systems, researchers thrive to achieve intuitiveness and facilitate the people's life through a thoughtful and in-depth study of several components of the application system that supports some…

Human-Computer Interaction · Computer Science 2018-12-05 Rui Portocarrero Sarmento , André Tarrinho , Pedro Câmara , Vera Costa

Antidepressant nonadherence is pervasive, driving relapse, hospitalization, suicide risk, and billions in avoidable costs. Clinicians need tools that detect adherence lapses promptly, yet current methods are either invasive (serum assays,…

Research is ongoing all over the world for identifying the barriers and finding effective solutions to accelerate the projection of Precision Medicine (PM) in the healthcare industry. Yet there has not been a valid and practical model to…

Computers and Society · Computer Science 2021-06-01 Nasim Sadat Mosavi , Manuel Filipe Santos

When the full stock of a new product is quickly sold in a few days or weeks, one has the impression that new technologies develop and conquer the market in a very easy way. This may be true for some new technologies, for example the cell…

Physics and Society · Physics 2012-08-14 Sebastian Goncalves , M. F. Laguna , J. R. Iglesias

The number of new cancer cases is expected to increase by about 50% in the next 20 years, and the need for chemotherapy treatments will increase accordingly. Chemotherapy treatments are usually performed in outpatient cancer centers where…

Optimization and Control · Mathematics 2023-09-15 Giuliana Carello , Mauro Passacantando , Elena Tanfani

The objective of this paper is to understand what characteristics and features of clinical data influence physician's decision about ordering laboratory tests or prescribing medications the most. We conduct our analysis on data and…

Machine Learning · Computer Science 2026-05-07 Michal Valko , Milos Hauskrecht

This paper shows how to use a randomized saturation experimental design to identify and estimate causal effects in the presence of spillovers--one person's treatment may affect another's outcome--and one-sided non-compliance--subjects can…

Opioid addiction has become a global epidemic and a national health crisis in recent years, with the number of opioid overdose fatalities steadily increasing since the 1990s. In contrast to the dynamics of a typical illicit drug or disease…

Populations and Evolution · Quantitative Biology 2019-05-03 Nicholas A. Battista , Leigh B. Pearcy , W. Christopher Strickland

Identifying optimal medical treatments to improve survival has long been a critical goal of pharmacoepidemiology. Traditionally, we use an average treatment effect measure to compare outcomes between treatment plans. However, new methods…

Modern healthcare facilities demand digital accessibility to guarantee equal access to telemedicine platforms, online pharmacy services, and health monitoring devices that can be worn or are handy. With the rising call for the…

Human-Computer Interaction · Computer Science 2025-06-02 Vishnu Ramineni , Balaji Shesharao Ingole , Nikhil Kumar Pulipeta , Balakrishna Pothineni , Aditya Gupta

Recent shifts in global health priorities have positioned Population Health Management (PHM) as a central area of focus. However, optimizing PHM strategies presents several challenges: managing high-dimensional patient covariates, tracking…

Optimization and Control · Mathematics 2026-04-10 Daniel Adelman , Alba V Olivares-Nadal , Miaolan Xie

Motivated by a study about prompt coronary angiography in myocardial infarction, we propose a method to estimate the causal effect of a treatment in two-arm experimental studies with possible non-compliance in both treatment and control…

Statistics Theory · Mathematics 2012-10-26 F. Bartolucci , A. Farcomeni

In the context of individual-level causal inference, we study the problem of predicting whether someone will respond or not to a treatment based on their features and past examples of features, treatment indicator (e.g., drug/no drug), and…

Machine Learning · Statistics 2019-06-04 Nathan Kallus

With today's technological advancements, mobile phones and wearable devices have become extensions of an increasingly diffused and smart digital infrastructure. In this paper, we examine mobile health (mHealth) platforms and their health…

General Economics · Economics 2021-02-18 Anindya Ghose , Xitong Guo , Beibei Li , Yuanyuan Dang

Internet-delivered psychological treatments (IDPT) are seen as an effective and scalable pathway to improving the accessibility of mental healthcare. Within this context, treatment adherence is an especially pertinent challenge to address…

Machine Learning · Computer Science 2022-09-07 Ulysse Côté-Allard , Minh H. Pham , Alexandra K. Schultz , Tine Nordgreen , Jim Torresen
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