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We establish necessary and sufficient conditions for consistent root reconstruction in continuous-time Markov models with countable state space on bounded-height trees. Here a root state estimator is said to be consistent if the probability…

Probability · Mathematics 2019-08-02 Wai-Tong Louis Fan , Sebastien Roch

In phylogenetic studies, biologists often wish to estimate the ancestral discrete character state at an interior vertex $v$ of an evolutionary tree $T$ from the states that are observed at the leaves of the tree. A simple and fast…

Populations and Evolution · Quantitative Biology 2018-05-03 Lina Herbst , Thomas Li , Mike Steel

In this paper we investigate mathematical questions concerning the reliability (reconstruction accuracy) of Fitch's maximum parsimony algorithm for reconstructing the ancestral state given a phylogenetic tree and a character. In particular,…

Populations and Evolution · Quantitative Biology 2009-07-06 Mareike Fischer , Bhalchandra D. Thatte

The evolution of aligned DNA sequence sites is generally modeled by a Markov process operating along the edges of a phylogenetic tree. It is well known that the probability distribution on the site patterns at the tips of the tree…

Populations and Evolution · Quantitative Biology 2013-10-15 Benny Chor , Mike Steel

One of the main aims in phylogenetics is the estimation of ancestral sequences based on present-day data like, for instance, DNA alignments. One way to estimate the data of the last common ancestor of a given set of species is to first…

Populations and Evolution · Quantitative Biology 2017-02-07 Lina Herbst , Mareike Fischer

Predicting the ancestral sequences of a group of homologous sequences related by a phylogenetic tree has been the subject of many studies, and numerous methods have been proposed to this purpose. Theoretical results are available that show…

Populations and Evolution · Quantitative Biology 2013-09-05 Olivier Gascuel , Mike Steel

Inferring the ancestral state at the root of a phylogenetic tree from states observed at the leaves is a problem arising in evolutionary biology. The simplest technique -- majority rule -- estimates the root state by the most frequently…

Populations and Evolution · Quantitative Biology 2014-04-11 Elchanan Mossel , Mike Steel

Applying a method to reconstruct a phylogenetic tree from random data provides a way to detect whether that method has an inherent bias towards certain tree `shapes'. For maximum parsimony, applied to a sequence of random 2-state data, each…

Populations and Evolution · Quantitative Biology 2014-06-03 Mareike Fischer , Michelle Galla , Lina Herbst , Mike Steel

For a tree Markov random field non-reconstruction is said to hold if as the depth of the tree goes to infinity the information that a typical configuration at the leaves gives about the value at the root goes to zero. The distribution of…

Discrete Mathematics · Computer Science 2011-07-28 Nayantara Bhatnagar , Elitza Maneva

Phylogenetic (i.e. leaf-labeled) trees play a fundamental role in evolutionary research. A typical problem is to reconstruct such trees from data like DNA alignments (whose columns are often referred to as characters), and a simple…

Populations and Evolution · Quantitative Biology 2022-09-08 Mareike Fischer

Likelihood-based methods are widely considered the best approaches for reconstructing ancestral states. Although much effort has been made to study properties of these methods, previous works often assume that both the tree topology and…

Methodology · Statistics 2021-04-02 Lam Si Tung Ho , Edward Susko

The hierarchical and recursive expressive capability of rooted trees is applicable to represent statistical models in various areas, such as data compression, image processing, and machine learning. On the other hand, such hierarchical…

Machine Learning · Computer Science 2022-01-25 Yuta Nakahara , Shota Saito , Akira Kamatsuka , Toshiyasu Matsushima

Methods of phylogenetic inference use more and more complex models to generate trees from data. However, even simple models and their implications are not fully understood. Here, we investigate the two-state Markov model on a tripod tree,…

Populations and Evolution · Quantitative Biology 2011-12-06 Steffen Klaere , Volkmar Liebscher

We consider a broadcasting problem on a tree where a binary digit (e.g., a spin or a nucleotide's purine/pyrimidine type) is propagated from the root to the leaves through symmetric noisy channels on the edges that randomly flip the state…

Probability · Mathematics 2025-01-24 David Clancy , Hanbaek Lyu , Sebastien Roch , Allan Sly

Understanding the evolution of binary traits, which affects the birth and survival of species and also the rate of molecular evolution, remains challenging. A typical example is the evolution of mating systems in plant species. In this…

Populations and Evolution · Quantitative Biology 2017-04-04 Daniah Tahir , Sylvain Glémin , Martin Lascoux , Ingemar Kaj

The structure of an evolving network contains information about its past. Extracting this information efficiently, however, is, in general, a difficult challenge. We formulate a fast and efficient method to estimate the most likely history…

Physics and Society · Physics 2020-09-16 Gábor Timár , Rui A. da Costa , Sergey N. Dorogovtsev , José F. F. Mendes

Ancestral state reconstruction is one of the most important tasks in evolutionary biology. Conditions under which we can reliably reconstruct the ancestral state have been studied for both discrete and continuous traits. However, the…

Populations and Evolution · Quantitative Biology 2021-11-16 Lam Si Tung Ho , Vu Dinh

We derive tractable criteria for the consistency of Bayesian tree reconstruction procedures, which constitute a central class of algorithms for inferring common ancestry among DNA sequence samples in phylogenetics. Our results encompass…

Statistics Theory · Mathematics 2025-08-05 Alisa Kirichenko , Luke J. Kelly , Jere Koskela

The reconstruction of a central tendency `species tree' from a large number of conflicting gene trees is a central problem in systematic biology. Moreover, it becomes particularly problematic when taxon coverage is patchy, so that not all…

Populations and Evolution · Quantitative Biology 2014-05-27 Mike Steel , Joel D. Velasco

The study of Markov processes and broadcasting on trees has deep connections to a variety of areas including statistical physics, graphical models, phylogenetic reconstruction, Markov Chain Monte Carlo, and community detection in random…

Probability · Mathematics 2022-10-26 Frederic Koehler , Elchanan Mossel
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