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Using numerical simulations, we characterized the behavior of an elastic membrane immersed in an active fluid. Our findings reveal a nontrivial folding and re-expansion of the membrane that is controlled by the interplay of its resistance…

Soft Condensed Matter · Physics 2015-07-24 S. A. Mallory , C. Valeriani , A. Cacciuto

Ciliary oscillations driven by molecular motors cause fluid motion at micron scale. Stable oscillations require a substantial source of dissipation to balance the energy input of motors. Conventionally, it stems from external fluid. We…

Soft Condensed Matter · Physics 2021-02-23 Debasmita Mondal , Ronojoy Adhikari , Prerna Sharma

The unicellular green algae Chlamydomonas swims with two flagella, which can synchronize their beat. Synchronized beating is required to swim both fast and straight. A long-standing hypothesis proposes that synchronization of flagella…

Cell Behavior · Quantitative Biology 2013-11-26 Veikko Geyer , Frank Jülicher , Jonathon Howard , Benjamin M Friedrich

Groups of eukaryotic cilia and flagella are capable of coordinating their beating over large scales, routinely exhibiting collective dynamics in the form of metachronal waves. The origin of this behaviour -- possibly influenced by both…

Soft Condensed Matter · Physics 2015-05-12 Douglas R. Brumley , Marco Polin , Timothy J. Pedley , Raymond E. Goldstein

Stick-slip motion, a common phenomenon observed during crawling of cells, is found to be strongly sensitive to the substrate stiffness. Stick-slip behaviours have previously been investigated typically using purely elastic substrates. For a…

Biological Physics · Physics 2019-07-31 Partho Sakha De , Rumi De

Assembly and stability of mitotic spindle is governed by the interplay of various intra-cellular forces, e.g. the forces generated by motor proteins by sliding overlapping anti-parallel microtubules (MTs) polymerized from the opposite…

Biological Physics · Physics 2016-08-24 Paolo Malgaretti , Sudipto Muhuri

We investigated self-sustained oscillation in a collapsible channel, in which a part of one rigid wall is replaced by a thin elastic wall, and synchronization phenomena in the two channels connected in parallel. We performed a…

Adaptation and Self-Organizing Systems · Physics 2024-05-08 Yuki Araya , Hiroaki Ito , Hiroyuki Kitahata

The initiation of directional cell motion requires symmetry breaking that can happen both with or without external stimuli. During cell crawling, forces generated by the cytoskeleton and their transmission through mechanosensitive adhesions…

Cell Behavior · Quantitative Biology 2023-06-02 Yuzhu Chen , David Saintillan , Padmini Rangamani

Using multiparticle collision dynamics simulations, we investigate the swimming dynamics, orientational behavior, and hydrodynamic interactions of a model swimmer designed to mimic the isolated flagellar apparatus ($FA$) of Chlamydomonas…

Biological Physics · Physics 2025-07-01 Sai Venkata Ramana Ambadipudi , Albert Bae , Azam Gholami

We demonstrate that internal pivot-like defects, arising from rigor mutant motor proteins that bind without stepping, fundamentally reshape the dynamics of semiflexible filaments in two-dimensional motility assays. Using large-scale…

Biological Physics · Physics 2025-09-29 Sandip Roy , Debasish Chaudhuri , Abhishek Chaudhuri

Eukaryotic cilia and flagella are chemo-mechanical oscillators capable of generating long-range coordinated motions known as metachronal waves. Pair synchronization is a fundamental requirement for these collective dynamics, but it is…

Biological Physics · Physics 2016-06-03 Douglas R. Brumley , Nicolas Bruot , Jurij Kotar , Raymond E. Goldstein , Pietro Cicuta , Marco Polin

In this fluid dynamics video, we demonstrate the microscale mixing enhancement of passive tracer particles in suspensions of swimming microalgae, Chlamydomonas reinhardtii. These biflagellated, single-celled eukaryotes (10 micron diameter)…

Recent advances in microscopy techniques has uncovered unique aspects of flagella-driven motility in bacteria. A remarkable example is the discovery of flagellar wrapping, a phenomenon whereby a bacterium wraps its flagellum (or flagellar…

Soft Condensed Matter · Physics 2025-04-22 Takuro Kataoka , Taiju Yoneda , Daisuke Nakane , Hirofumi Wada

Many bacteria are motile by means of one or more rotating rigid helical flagella, making them the only known organism to use rotation as a means of propulsion. The rotation is supplied by the bacterial flagellar motor, a particularly…

Flagella allow eukaryotic cells to move and pump fluid. We present the first three-dimensional, time-resolved imaging of the flagellar waveform of Chlamydomonas reinhardtii, a model alga found in fresh water. During the power stroke, we…

Biological Physics · Physics 2022-10-18 Laurence G. Wilson , Martin A. Bees

Flexible filaments moving in viscous fluids are ubiquitous in the natural microscopic world. For example, the swimming of bacteria and spermatozoa as well as important physiological functions at organ-level, such as the cilia-induced motion…

Soft Condensed Matter · Physics 2019-06-05 Panayiota Katsamba , Eric Lauga

Suspensions of unicellular microswimmers such as flagellated bacteria or motile algae exhibit spontaneous density heterogeneities at large enough concentrations. Based on the relative location of the biological actuation appendages i.e.…

Soft Condensed Matter · Physics 2017-11-27 Fabian Jan Schwarzendahl , Marco G. Mazza

We present a generic theory for the dynamics of a stiff filament under tension, in an active medium with orientational correlations, such as a microtubule in contractile actin. In sharp contrast to the case of a passive medium, we find the…

Soft Condensed Matter · Physics 2009-01-28 Norio Kikuchi , Allen Ehrlicher , Daniel Koch , Josef A. Käs , Sriram Ramaswamy , Madan Rao

Exploiting the "natural" frame of space curves, we formulate an intrinsic dynamics of twisted elastic filaments in viscous fluids. A pair of coupled nonlinear equations describing the temporal evolution of the filament's complex curvature…

Soft Condensed Matter · Physics 2009-10-31 Raymond E. Goldstein , Thomas R. Powers , Chris H. Wiggins

Observations of single epidermal cells on flat adhesive substrates have revealed two distinct morphological and functional states, namely a non-migrating symmetric unpolarized state and a migrating asymmetric polarized state. These states…

Biological Physics · Physics 2010-04-14 Wolfgang Alt , Martin Bock , Christoph Möhl