Related papers: Bistability in the synchronization of actuated mic…
During cell division, sister chromatids are segregated by the mitotic spindle, a bipolar assembly of interdigitating antiparallel polar filaments called microtubules. Establishing a stable overlap region is essential for maintenance of…
In the cellular phenomena of cytoplasmic streaming, molecular motors carrying cargo along a network of microtubules entrain the surrounding fluid. The piconewton forces produced by individual motors are sufficient to deform long…
We study synchronization of two cardiomyocytes mediated by elastic interactions through the substrate. Modeling each cell as an oscillating force dipole governed by a Rayleigh-type equation, we derive an effective mechanical coupling from…
Effective organismal behavior responds appropriately to changes in the surrounding environment. Attaining this delicate balance of sensitivity and stability is a hallmark of the animal kingdom. By studying the locomotory behavior of a…
Active filaments are a workhorse for propulsion and actuation across biology, soft robotics and mechanical metamaterials. However, artificial active rods suffer from limited robustness and adaptivity because they rely on external control,…
The motility of eukaryotic cells is strongly influenced by their environment, with confined cells often developing qualitatively different motility patterns from those migrating on simple two-dimensional substrates. Recent experiments,…
In cells, cytoskeletal filament networks are responsible for cell movement, growth, and division. Filaments in the cytoskeleton are driven and organized by crosslinking molecular motors. In reconstituted cytoskeletal systems, motor activity…
We study a simple two-dimensional model for motion of an elastic filament subject to internally generated stresses and show that wave-like propagating shapes which can propel the filament can be induced by a self-organized mechanism via a…
We present a general theoretical analysis of semiflexible filaments subject to viscous drag or point forcing. These are the relevant forces in dynamic experiments designed to measure biopolymer bending moduli. By analogy with the ``Stokes…
We discuss a two-dimensional model for the dynamics of axonemal deformations driven by internally generated forces of molecular motors. Our model consists of an elastic filament pair connected by active elements. We derive the dynamic…
We investigate synchronization and metachronal-wave formation in a one-dimensional array of eukaryotic flagella using an elastohydrodynamic model. In contrast to a two-flagellum system, where only in-phase synchronization is stable, larger…
Active deformable filaments exhibit a large range of qualitatively different three-dimensional dynamics, depending on their flexibility, the strength and nature of the active forcing, and the surrounding environment. We investigate the…
The conditions under which biological cells switch from a static to a motile state are fundamental to the understanding of many healthy and pathological processes. In this paper, we show that even in the presence of a fully symmetric…
Carpets of actively bending cilia represent arrays of biological oscillators that can exhibit self-organized metachronal synchronization in the form of traveling waves of cilia phase. This metachronal coordination supposedly enhances fluid…
Activity can organize matter in unique configurations inaccessible to equilibrium systems, including a sundry of spiraling shapes seen in nature that range from galaxies to living tissues to fossilized stromatolites. How these dynamic yet…
We study synchronization in large populations of coupled phase oscillators with time-delays, higher order interactions. With each of these effects individually giving rise to bistabiltiy between incoherence and synchronization via a…
Dynamic mitigation is presented for filamentation instability and magnetic reconnection in a plasm driven by a wobbling electron sheet current. The wobbling current introduces an oscillating perturbation and smooths the perturbation. The…
Many eukaryotic microorganisms propelled by multiple flagella can swim very rapidly with distinct gaits. Here, we model a three-dimensional mutiflagellate swimming strategy, resembling the microalgae, and investigate the effects of…
Interactions between microorganisms and solid boundaries play an important role in biological processes, like egg fertilisation, biofilm formation and soil colonisation, where microswimmers move within a structured environment. Despite…
Peritrichously-flagellated bacteria, such as Escherichia coli, self-propel in fluids by using specialised motors to rotate multiple helical filaments. The rotation of each motor is transmitted to a short flexible segment called the hook…