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Advances in machine learning and the increasing availability of high-dimensional data have led to the proliferation of social science research that uses the predictions of machine learning models as proxies for measures of human activity or…

Machine Learning · Computer Science 2025-02-19 Luke C Sanford , Megan Ayers , Matthew Gordon , Eliana Stone

Understanding effect modification -- how treatment effects vary across subpopulations -- is practically important in observational studies, as it helps identify which subgroups are likely to benefit from a given treatment. In this paper, we…

Methodology · Statistics 2026-05-12 Yu Gui , Dylan S Small , Zhimei Ren

We study regression adjustment with general function class approximations for estimating the average treatment effect in the design-based setting. Standard regression adjustment involves bias due to sample re-use, and this bias leads to…

Methodology · Statistics 2023-11-17 Fangzhou Su , Wenlong Mou , Peng Ding , Martin J. Wainwright

Many causal and structural effects depend on regressions. Examples include policy effects, average derivatives, regression decompositions, average treatment effects, causal mediation, and parameters of economic structural models. The…

Statistics Theory · Mathematics 2022-10-25 Victor Chernozhukov , Whitney K Newey , Rahul Singh

An adaptive design adjusts dynamically as information is accrued and a consequence of applying an adaptive design is the potential for inducing small-sample bias in estimates. In psychometrics and psychophysics, a common class of studies…

Methodology · Statistics 2025-02-17 Simon Bang Kristensen , Katrine Bødkergaard , Bo Martin Bibby

Large-scale industrial recommendation models predict the most relevant items from catalogs containing millions or billions of options. To train these models efficiently, a small set of irrelevant items (negative samples) is selected from…

Information Retrieval · Computer Science 2024-10-30 Arushi Prakash , Dimitrios Bermperidis , Srivas Chennu

Sampling biases in training data are a major source of algorithmic biases in machine learning systems. Although there are many methods that attempt to mitigate such algorithmic biases during training, the most direct and obvious way is…

Machine Learning · Statistics 2022-04-15 Laura Niss , Yuekai Sun , Ambuj Tewari

In randomized experiments, the actual treatments received by some experimental units may differ from their treatment assignments. This non-compliance issue often occurs in clinical trials, social experiments, and the applications of…

Methodology · Statistics 2022-04-19 Jiyang Ren

Modern science increasingly relies on ever-growing observational datasets and automated inference pipelines, under the implicit belief that accumulating more data makes scientific conclusions more reliable. Here we show that this belief can…

Machine Learning · Computer Science 2026-02-06 Zhipeng Zhang , Kai Li

Failure to accurately measure the outcomes of an experiment can lead to bias and incorrect conclusions. Online controlled experiments (aka AB tests) are increasingly being used to make decisions to improve websites as well as mobile and…

Other Computer Science · Computer Science 2019-04-01 Jayant Gupchup , Yasaman Hosseinkashi , Pavel Dmitriev , Daniel Schneider , Ross Cutler , Andrei Jefremov , Martin Ellis

Predictive models often reinforce biases which were originally embedded in their training data, through skewed decisions. In such cases, mitigation methods are critical to ensure that, regardless of the prevailing disparities, model…

Machine Learning · Statistics 2025-07-15 Ricardo Inácio , Zafeiris Kokkinogenis , Vitor Cerqueira , Carlos Soares

This paper studies inference in randomized controlled trials with covariate-adaptive randomization when there are multiple treatments. More specifically, we study inference about the average effect of one or more treatments relative to…

Econometrics · Economics 2019-01-21 Federico A. Bugni , Ivan A. Canay , Azeem M. Shaikh

In noisy evolutionary optimization, sampling is a common strategy to deal with noise. By the sampling strategy, the fitness of a solution is evaluated multiple times (called \emph{sample size}) independently, and its true fitness is then…

Neural and Evolutionary Computing · Computer Science 2022-11-29 Chao Qian , Chao Bian , Yang Yu , Ke Tang , Xin Yao

Concerns have been expressed over the validity of statistical inference under covariate-adaptive randomization despite the extensive use in clinical trials. In the literature, the inferential properties under covariate-adaptive…

Methodology · Statistics 2022-07-05 Li Yang , Wei Ma , Yichen Qin , Feifang Hu

We consider large-scale studies in which it is of interest to test a very large number of hypotheses, and then to estimate the effect sizes corresponding to the rejected hypotheses. For instance, this setting arises in the analysis of gene…

Methodology · Statistics 2015-03-31 Kean Ming Tan , Noah Simon , Daniela Witten

We present an empirical study of debiasing methods for classifiers, showing that debiasers often fail in practice to generalize out-of-sample, and can in fact make fairness worse rather than better. A rigorous evaluation of the debiasing…

Covariate-adaptive randomization (CAR) procedures are frequently used in comparative studies to increase the covariate balance across treatment groups. However, because randomization inevitably uses the covariate information when forming…

Statistics Theory · Mathematics 2022-07-08 Wei Ma , Yichen Qin , Yang Li , Feifang Hu

Observational studies are a key resource for causal inference but are often affected by systematic biases. Prior work has focused mainly on detecting these biases, via sensitivity analyses and comparisons with randomized controlled trials,…

Methodology · Statistics 2025-06-03 Ilker Demirel , Zeshan Hussain , Piersilvio De Bartolomeis , David Sontag

The effect of bias on hypothesis formation is characterized for an automated data-driven projection pursuit neural network to extract and select features for binary classification of data streams. This intelligent exploratory process…

Machine Learning · Computer Science 2022-01-05 John Patterson , Chris Avery , Tyler Grear , Donald J. Jacobs

On-line experimentation (also known as A/B testing) has become an integral part of software development. To timely incorporate user feedback and continuously improve products, many software companies have adopted the culture of agile…

Applications · Statistics 2019-08-13 Yu Wang , Somit Gupta , Jiannan Lu , Ali Mahmoudzadeh , Sophia Liu