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Data that is gathered adaptively --- via bandit algorithms, for example --- exhibits bias. This is true both when gathering simple numeric valued data --- the empirical means kept track of by stochastic bandit algorithms are biased…

Machine Learning · Computer Science 2018-06-07 Seth Neel , Aaron Roth

In adaptive clinical trials, the conventional end-of-trial point estimate of a treatment effect is prone to bias, that is, a systematic tendency to deviate from its true value. As stated in recent FDA guidance on adaptive designs, it is…

Adaptive collection of data is commonplace in applications throughout science and engineering. From the point of view of statistical inference however, adaptive data collection induces memory and correlation in the samples, and poses…

Methodology · Statistics 2020-05-07 Yash Deshpande , Adel Javanmard , Mohammad Mehrabi

Algorithms and technologies are essential tools that pervade all aspects of our daily lives. In the last decades, health care research benefited from new computer-based recruiting methods, the use of federated architectures for data…

Computers and Society · Computer Science 2023-01-26 Chiara Criscuolo , Tommaso Dolci , Mattia Salnitri

Data from both a randomized trial and an observational study are sometimes simultaneously available for evaluating the effect of an intervention. The randomized data typically allows for reliable estimation of average treatment effects but…

Methodology · Statistics 2021-12-01 David Cheng , Tianxi Cai

The Hot Stove Effect is a negativity bias resulting from the adaptive character of learning. The mechanism is that learning algorithms that pursue alternatives with positive estimated values, but avoid alternatives with negative estimated…

Machine Learning · Computer Science 2024-04-04 Jerker Denrell

Data can be collected in scientific studies via a controlled experiment or passive observation. Big data is often collected in a passive way, e.g. from social media. In studies of causation great efforts are made to guard against bias and…

Methodology · Statistics 2018-11-21 Elena Pesce , Eva Riccomagno , Henry P. Wynn

We provide an approach to exploratory data analysis in matched observational studies with a single intervention and multiple endpoints. In such settings, the researcher would like to explore evidence for actual treatment effects among these…

Methodology · Statistics 2025-12-10 Mengqi Lin , Colin Fogarty

Recent FDA guidance on adaptive clinical trial designs defines bias as "a systematic tendency for the estimate of treatment effect to deviate from its true value", and states that it is desirable to obtain and report estimates of treatment…

Imbalanced data, where the positive samples represent only a small proportion compared to the negative samples, makes it challenging for classification problems to balance the false positive and false negative rates. A common approach to…

Machine Learning · Statistics 2026-02-17 Pengfei Lyu , Zhengchi Ma , Linjun Zhang , Anru R. Zhang

In recent years, real-world external controls have grown in popularity as a tool to empower randomized placebo-controlled trials, particularly in rare diseases or cases where balanced randomization is unethical or impractical. However, as…

Methodology · Statistics 2024-11-14 Chenyin Gao , Shu Yang , Mingyang Shan , Wenyu Ye , Ilya Lipkovich , Douglas Faries

An increased awareness concerning risks of algorithmic bias has driven a surge of efforts around bias mitigation strategies. A vast majority of the proposed approaches fall under one of two categories: (1) imposing algorithmic fairness…

Machine Learning · Computer Science 2023-07-11 Yunyi Li , Maria De-Arteaga , Maytal Saar-Tsechansky

Active learning is a powerful tool when labelling data is expensive, but it introduces a bias because the training data no longer follows the population distribution. We formalize this bias and investigate the situations in which it can be…

Machine Learning · Statistics 2021-06-01 Sebastian Farquhar , Yarin Gal , Tom Rainforth

Self-supervised representation learning on image-text data facilitates crucial medical applications, such as image classification, visual grounding, and cross-modal retrieval. One common approach involves contrasting semantically similar…

Machine Learning · Computer Science 2023-08-15 Peiqi Wang , Yingcheng Liu , Ching-Yun Ko , William M. Wells , Seth Berkowitz , Steven Horng , Polina Golland

Biases in existing datasets used to train algorithmic decision rules can raise ethical and economic concerns due to the resulting disparate treatment of different groups. We propose an algorithm for sequentially debiasing such datasets…

Machine Learning · Computer Science 2023-01-11 Yifan Yang , Yang Liu , Parinaz Naghizadeh

Recommender systems rely on user behavior data like ratings and clicks to build personalization model. However, the collected data is observational rather than experimental, causing various biases in the data which significantly affect the…

Machine Learning · Computer Science 2021-10-29 Jiawei Chen , Hande Dong , Yang Qiu , Xiangnan He , Xin Xin , Liang Chen , Guli Lin , Keping Yang

Every design choice will have different effects on different units. However traditional A/B tests are often underpowered to identify these heterogeneous effects. This is especially true when the set of unit-level attributes is…

Artificial Intelligence · Computer Science 2016-11-09 Alexander Peysakhovich , Akos Lada

The widespread use of machine learning and data-driven algorithms for decision making has been steadily increasing over many years. \emph{Bias} in the data can adversely affect this decision-making. We present a new mitigation strategy to…

Machine Learning · Computer Science 2025-07-25 Bruno Scarone , Alfredo Viola , Renée J. Miller , Ricardo Baeza-Yates

Attrition is a common and potentially important threat to internal validity in treatment effect studies. We extend the changes-in-changes approach to identify the average treatment effect for respondents and the entire study population in…

Econometrics · Economics 2024-03-29 Dalia Ghanem , Sarojini Hirshleifer , Désiré Kédagni , Karen Ortiz-Becerra

Indirect experiments provide a valuable framework for estimating treatment effects in situations where conducting randomized control trials (RCTs) is impractical or unethical. Unlike RCTs, indirect experiments estimate treatment effects by…

Machine Learning · Computer Science 2023-12-06 Yash Chandak , Shiv Shankar , Vasilis Syrgkanis , Emma Brunskill
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