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200 papers

Lumen formation plays an essential role in the morphogenesis of tissues during development. Here we review the physical principles that play a role in the growth and coarsening of lumens. Solute pumping by the cell, hydraulic flows driven…

Soft Condensed Matter · Physics 2021-07-14 Alejandro Torres-Sánchez , Max Kerr Winter , Guillaume Salbreux

Oscillatory activities are widely observed in specific frequency bands of recorded field potentials in different brain regions, and play critical roles in processing neural information. Understanding the structure of these oscillatory…

Neurons and Cognition · Quantitative Biology 2015-07-23 Pengsheng Zheng

Cell motility in viscous fluids is ubiquitous and affects many biological processes, including reproduction, infection, and the marine life ecosystem. Here we review the biophysical and mechanical principles of locomotion at the small…

Soft Condensed Matter · Physics 2009-09-16 Eric Lauga , Thomas R. Powers

The lecture introduces a reader to the relatively young field of physics of strongly interacting and disordered 2D electron system, in particular, to the phenomena of the metallic conduction and the apparent metal-insulator transition in…

Strongly Correlated Electrons · Physics 2014-03-27 V. M. Pudalov

Large-scale white matter pathways crisscrossing the cortex create a complex pattern of connectivity that underlies human cognitive function. Generative mechanisms for this architecture have been difficult to identify in part because little…

Neurons and Cognition · Quantitative Biology 2015-06-16 Florian Klimm , Danielle S. Bassett , Jean M. Carlson , Peter J. Mucha

Many cellular processes require a polarization axis which generally initially emerges as an inhomogeneous distribution of molecular markers in the cell. We present a simple analytical model of a general mechanism of cell polarization taking…

Cell Behavior · Quantitative Biology 2009-10-21 Rhoda J. Hawkins , Olivier Benichou , Matthieu Piel , Raphael Voituriez

Motivated by the formation of ring-like filament structures in the cortex of plant and animal cells, we study the dynamics of a two-dimensional layer of cytoskeletal filaments and motor proteins near a surface by a general continuum theory.…

Subcellular Processes · Quantitative Biology 2009-11-11 Alexander Zumdieck , Marco Cosentino Lagomarsino , Catalin Tanase , Karsten Kruse , Bela Mulder , Marileen Dogterom , Frank J"ulicher

The origin of biological motion can be traced back to the function of molecular motor proteins. Cytoplasmic dynein and kinesin transport organelles within our cells moving along a polymeric filament, the microtubule. The motion of the…

Statistical Mechanics · Physics 2015-06-25 Imre Derenyi , Tamas Vicsek

This paper is devoted to the study of symplectic manifolds and their connection with Hamiltonian dynamical systems. We review some properties and operations on these manifolds and see how they intervene when studying the complete…

Symplectic Geometry · Mathematics 2019-04-03 A. Lesfari

Modeling of consciousness-related phenomena and neuroengineering are fields that are rapidly growing together. We review recent approaches and developments and point out some promising directions of future research: Understanding the…

Neurons and Cognition · Quantitative Biology 2013-12-31 Jens Christian Claussen , Ulrich G. Hofmann

Recent studies suggest a potential link between the physical structure of mitochondria and neurodegenerative diseases. With advances in Electron Microscopy techniques, it has become possible to visualize the boundary and internal membrane…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Faris Serdar Taşel , Efe Çiftci

Cellular membranes are elastic lipid bilayers that contain a variety of proteins, including ion channels, receptors, and scaffolding proteins. These proteins are known to diffuse in the plane of the membrane and to influence the bending of…

Soft Condensed Matter · Physics 2020-10-28 Arijit Mahapatra , David Saintillan , Padmini Rangamani

The occurrence of in-stent restenosis following percutaneous coronary intervention highlights the need for the creation of computational tools that can extract pathophysiological insights and optimize interventional procedures on a…

Dynamic instability in the cytoskeleton underlies a great many vital cellular processes. In neurons, it is thought to play a role in information processing and the establishment of synaptic connections. It is from this interneuronal…

Medical Physics · Physics 2019-12-19 Gweneth Andersen

Magnetic skyrmions are spin swirling solitonic defects that can play a major role in information technology. Their future in applications and devices hinges on their efficient manipulation and detection. Here, we explore from ab-initio…

Mesoscale and Nanoscale Physics · Physics 2021-01-18 Mohammed Bouhassoune , Samir Lounis

Protein pattern formation is essential for the spatial organization of many intracellular processes like cell division, flagellum positioning, and chemotaxis. A prominent example of intracellular patterns are the oscillatory pole-to-pole…

Biological Physics · Physics 2018-02-21 Erwin Frey , Jacob Halatek , Simon Kretschmer , Petra Schwille

Probabilistic inference offers a principled framework for understanding both behaviour and cortical computation. However, two basic and ubiquitous properties of cortical responses seem difficult to reconcile with probabilistic inference:…

Neurons and Cognition · Quantitative Biology 2017-01-03 Laurence Aitchison , Máté Lengyel

Heteroclinic dynamics is a suitable framework for describing transient and reproducible dynamics such as cognitive processes in the brain. We demonstrate how heteroclinic units can act as pacemakers to entrain larger sets of units from a…

Dynamical Systems · Mathematics 2022-07-22 Bhumika Thakur , Hildegard Meyer-Ortmanns

Background: Sphingolipids - as suggested by the prefix in their name - are mysterious molecules, which play surprisingly various roles in opposable cellular processes, like autophagy, apoptosis, proliferation and differentiation. Recently…

Molecular Networks · Quantitative Biology 2014-11-11 Agata Charzyńska , Weronika Wronowska , Karol Nienałtowski , Anna Gambin

Imaging neuroscience links brain activation maps to behavior and cognition via correlational studies. Due to the nature of the individual experiments, based on eliciting neural response from a small number of stimuli, this link is…

Machine Learning · Statistics 2013-11-21 Yannick Schwartz , Bertrand Thirion , Gaël Varoquaux