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Cognitive function requires the coordination of neural activity across many scales, from neurons and circuits to large-scale networks. As such, it is unlikely that an explanatory framework focused upon any single scale will yield a…
Hyaluronic acid is an abundant polyelectrolyte in the human body that forms extracellular hydrogels in connective tissues. It is essential for regulating tissue biomechanics and cell-cell communication, yet hyaluronan overexpression is…
Metabolic substrates, such as oxygen and glucose, are rapidly delivered to the cell through filtration across microvessels walls. Modelling this important process is complicated by the coupling between flow and transport equations, which…
Membrane Proteins (MPs) account for around 15-39% of the human proteome and assume a critical role in a vast set of cellular and physiological mechanisms, including molecular transport, nutrient uptake, toxin and waste product clearance,…
This article aims at giving a general presentation of spintronics, an important field of research developing today along many new directions in physics of condensed matter. We tried to present simply the physical phenomena involved in…
Topological data analyses are rapidly turning into key tools for quantifying large volumes of neurobiological data, e.g., for organizing the spiking outputs of large neuronal ensembles and thus gaining insights into the information produced…
The accumulation of potassium in the extracellular space surrounding nerve cells is a fundamental aspect of biophysics that has garnered significant attention in recent research. This phenomenon holds implications for various neurological…
Many fundamental biological processes are dependent on cellular migration. Although the mechanical mechanisms of single-cell migration are relatively well understood, those underlying migration of multiple cells adhered to each other in a…
Understanding the mechanisms of interactions within cells, tissues, and organisms is crucial to driving developments across biology and medicine. Mathematical modeling is an essential tool for simulating biological systems and revealing…
We review evidence supporting the role of early life programming in the susceptibility for adult neurodegenerative diseases while highlighting questions and proposing avenues for future research to advance our understanding of this…
Can deep learning (DL) guide our understanding of computations happening in biological brain? We will first briefly consider how DL has contributed to the research on visual object recognition. In the main part we will assess whether DL…
Cellular uptake through the lipid membranes plays an important role in adsorbing nutrients and fighting infection and can be used for drug delivery and nanomedicine developments. Endocytosis is one of the known pathways of the cellular…
Molecular communication (MC) within the synaptic cleft is vital for neurotransmitter diffusion, a process critical to cognitive functions. In Alzheimer's Disease (AD), beta-amyloid oligomers (A$\beta$os) disrupt this communication, leading…
Background: Mathematical modeling approaches are becoming ever more established in clinical neuroscience. They provide insight that is key to understand complex interactions of network phenomena, in general, and interactions within the…
This paper attempts to review our studies on the propagation of signals in nerves over the past decade. The need for interdisciplinary studies is stressed that helps to understand the physical mechanisms of coupling the electrical,…
Endocytosis is an essential process by which cells internalize a piece of plasma membrane and material from the outside. In cells with turgor, pressure opposes membrane defor- mations, and increases the amount of force that has to be…
The unique dynamical features of the critical state endow the brain with properties which are fundamental for adaptive behavior. This proposal, put forward with Per Bak several years ago, is now supported by a wide body of empirical…
Contents: 1. Pomeron physics 2. Multiplicities 3. Single-particle distributions 4. Correlations and fluctuations 5. Special final states and interaction mechanisms 6. Cosmic rays and forward detectors
The ubiquity of topographic maps in the brain has long been known, and molecular mechanisms for the formation of topographic organization of neural systems have been revealed. Less attention has been given to the question of why are the…
Molecular spintronics is recognized to as an attractive new research direction in a field of spintronics, following to metallic spintronics and inorganic semiconductor spintronics, and attracts many people in recent decades. The purpose of…