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The network architecture of the human brain has become a feature of increasing interest to the neuroscientific community, largely because of its potential to illuminate human cognition, its variation over development and aging, and its…

Neurons and Cognition · Quantitative Biology 2016-11-07 Richard F. Betzel , Danielle S. Bassett

The different active roles of neurons and astrocytes during neuronal activation are associated with the metabolic processes necessary to supply the energy needed for their respective tasks at rest and during neuronal activation. Metabolism,…

Tissues and Organs · Quantitative Biology 2022-11-07 Gideon Idumah , Erkki Somersalo , Daniela Calvetti

Cell crawling on flat substrates is based on intracellular flows of the actin cytoskeleton that are driven by both actin polymerization at the front and myosin contractility at the back. The new experimental tool of optogenetics makes it…

Subcellular Processes · Quantitative Biology 2023-07-04 Oliver M. Drozdowski , Falko Ziebert , Ulrich S. Schwarz

This paper investigates and compares through a comprehensive TCAD analysis 2D and 3D simulations for ferroelectric based FETs. We provide clear evidence that the multiple read conductance values experimentally observed in FeFETs stem from…

Emerging Technologies · Computer Science 2023-08-29 Daniel Lizzit , Thomas Bernardi , David Esseni

Dendritic spines are key structural components of excitatory synapses in the brain. Given the size of dendritic spines provides a proxy for synaptic efficacy, their detection and tracking across time is important for studies of the neural…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Pamela Osuna-Vargas , Altug Kamacioglu , Dominik F. Aschauer , Petros E. Vlachos , Sercan Alipek , Jochen Triesch , Simon Rumpel , Matthias Kaschube

The brain may be thought of as a many-body architecture with a spatio-temporal dynamics described by neuronal structures. The oscillatory nature of brain activity allows these structures (nodes) to be described as a set of coupled…

Neurons and Cognition · Quantitative Biology 2021-02-03 J. Mendoza-Ruiz , C. E. Alonso-Malaver , M. Valderrama , O. A. Rosso , J. H. Martínez

A common developmental process, called branching morphogenesis, generates the epithelial trees in a variety of organs, including the lungs, kidneys, and glands. How branching morphogenesis can create epithelial architectures of very…

Tissues and Organs · Quantitative Biology 2021-03-02 Christine Lang , Lisa Conrad , Dagmar Iber

A major part of membrane function is conducted by proteins, both integral and peripheral. Peripheral membrane proteins temporarily adhere to biological membranes, either to the lipid bilayer or to integral membrane proteins with…

Biomolecules · Quantitative Biology 2014-06-27 Katerina C. Nastou , Georgios N. Tsaousis , Kimon E. Kremizas , Zoi I. Litou , Stavros J. Hamodrakas

Cerebellum is part of the brain that occupies only 10% of the brain volume, but it contains about 80% of total number of brain neurons. New cerebellar function model is developed that sets cerebellar circuits in context of multibody…

Neural and Evolutionary Computing · Computer Science 2014-02-25 Lavdim Kurtaj , Ilir Limani , Vjosa Shatri , Avni Skeja

Many cell functions are accomplished thanks to intracellular transport mechanisms of macromolecules along filaments. Molecular motors such as dynein or kinesin are proteins playing a primary role in these processes. The behavior of such…

Chaotic Dynamics · Physics 2010-12-21 Donatello Materassi , Subhrajit Roychowdhury , Murti V. Salapaka

We show that many perception tasks, from visual recognition, semantic segmentation, optical flow, depth estimation to vocalization discrimination, are highly redundant functions of their input data. Images or spectrograms, projected into…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Rahul Ramesh , Anthony Bisulco , Ronald W. DiTullio , Linran Wei , Vijay Balasubramanian , Kostas Daniilidis , Pratik Chaudhari

Molecules provide the ultimate language in terms of which physiology and pathology must be understood. Myriads of proteins participate in elaborate networks of interactions and perform chemical activities coordinating the life of cells. To…

Biomolecules · Quantitative Biology 2025-02-10 R. Gonzalo Parra , Elizabeth A. Komives , Peter G. Wolynes , Diego U. Ferreiro

The integration and transmission of information in the brain are dependent on the interplay between structural and dynamical properties. Implicit in any pursuit aimed at understanding neural dynamics from appropriate sets of mathematically…

Neurons and Cognition · Quantitative Biology 2020-06-30 Joshua M. Roldan , Sebastian Pardo G. , Vivek Kurien George , Gabriel A. Silva

Functional amyloid fibrils, once primarily associated with amyloidosis, are now recognized for their exceptional potential as biomaterials due to their unique structural features, including remarkable mechanical strength, high stability,…

Biomolecules · Quantitative Biology 2025-04-23 Shayan Mortazavi , Mehrnoosh Neshatian , Laurent Bozec , Hadis Zarrin , Mahshid Kalani

Though membrane trafficking of cell junction proteins has been studied extensively for more than two decades, the accumulated knowledge remains fragmentary. The goal of this review is to synthesize published studies on the membrane…

Subcellular Processes · Quantitative Biology 2021-04-13 Arie Horowitz

Convolution and deconvolution are essential techniques in various fields, notably in medical imaging, where they play a crucial role in analyzing dynamic processes such as blood flow. This paper explores the convolution and deconvolution of…

Image and Video Processing · Electrical Eng. & Systems 2024-03-01 Ishmael N. Amartey , Andreas A. Linninger , Thomas Ventimiglia

Axons functionally link the somato-dendritic compartment to synaptic terminals. Structurally and functionally diverse, they accomplish a central role in determining the delays and reliability with which neuronal ensembles communicate. By…

Neurons and Cognition · Quantitative Biology 2019-05-07 Pepe Alcami , Ahmed El Hady

Synchronous and directed ciliary beating in trachea allows transport and ejection of virus and dust from the body. This ciliary function depends on the coordinated configuration of basal bodies (root of cilia) in apical cell membrane.…

Cell Behavior · Quantitative Biology 2020-03-19 Toshinori Namba , Shuji Ishihara

The transition between epithelial and mesenchymal (EMT) is a fundamental cellular process that plays critical roles in development, cancer metastasis, and tissue wound healing. EMT is not a binary process but involves multiple partial EMT…

Cell Behavior · Quantitative Biology 2019-05-22 Jianhua Xing , Xiao-Jun Tian

The structure of membrane-active peptides and their interaction with lipid bilayers can be studied in oriented lipid membranes deposited on solid substrates. Such systems are desirable for a number of surface-sensitive techniques. Here we…

Soft Condensed Matter · Physics 2015-04-10 Chenghao Li , Doru Constantin , Tim Salditt