Related papers: Myelin and saltatory conduction
Membrane organization is essential for cellular functions such as signal transduction and membrane trafficking. A major challenge is to understand the lateral heterogeneous structures in membranes and membrane fluidity in the presence of…
Myelin figures are interfacial structures formed when certain surfactants swell in excess water. Here, I present data and model calculations suggesting myelin formation and growth is due to the fluid flow of surfactant, driven by the…
In a many body system, constituents interact with each other, forming a recursive pattern of interaction and giving rise to many interesting phenomena. Based upon concepts of the modern many body theory, a model for a generic many body…
During embryonic development, regeneration and homeostasis, cells have to physically integrate into their target tissues, where they ultimately execute their function. Despite a significant body of research on how mechanical forces instruct…
Cellular appendages such as cilia and flagella represent universal tools enabling cells and microbes, among other essential functionalities, to propel themselves in diverse environments. In its planktonic, i.e. freely swimming, state the…
The human brain is a complex network that supports mental function. The nascent field of network neuroscience applies tools from mathematics to neuroimaging data in the hopes of shedding light on cognitive function. A critical question…
This paper presents the basic ideas and properties of elliptic functions and elliptic integrals as an expository essay. It explores some of their numerous consequences and includes applications to some problems such as the simple pendulum,…
Biologically important membrane channels are gated by force at attached tethers. Here, we generically characterize the non-trivial interplay of force, membrane tension, and channel deformations that can affect gating. A central finding is…
Surface assays, such as ELISA and immunofluorescence, are nothing short of ubiquitous in biotechnology and medical diagnostics today. The development and optimization of these assays generally focuses on three aspects: immobilization…
The brain is a complex system comprising a myriad of interacting elements, posing significant challenges in understanding its structure, function, and dynamics. Network science has emerged as a powerful tool for studying such intricate…
Biological membranes and vesicles play a central role in living systems, forming dynamic interfaces that regulate cellular organization and function. Classical descriptions of membrane mechanics that are rooted in equilibrium statistical…
The mechanisms underlying major aspects of the human brain remain a mystery. It is unknown how verbal episodic memory is formed and integrated with sensory episodic memory. There is no consensus on the function and nature of dreaming. Here…
In this perspective we describe the critical role membranes play in modulating the structures of the Amyloid Precursor Proteins to produce the peptides involved in the Alzheimer's disease. Some of the key concepts related to protein…
Biological systems are influenced by fluid mechanics at nearly all spatiotemporal scales. This broad relevance of fluid mechanics to biology has been increasingly appreciated by engineers and biologists alike, leading to continued expansion…
In the human brain, white matter development is a complex and long-lasting process involving intermingling micro-and macrostructural mechanisms, such as fiber growth, pruning and myelination. Did you know that all these neurodevelopmental…
Magnetic fluids are colloidal suspensions of ferromagnetic particles covered with a surfactant layer, dispersed in a host liquid. The existence of cooperative phenomena in such magnetic colloidal systems, makes the determining of their…
Recent advancements in the ability to construct three-dimensional (3D) tissues and organoids from stem cells and biomaterials have not only opened abundant new research avenues in disease modeling and regenerative medicine but also have…
Cue integration, the combination of different sources of information to reduce uncertainty, is a fundamental computational principle of brain function. Starting from a normative model we show that the dynamics of multi-compartment neurons…
Over the past few decades, magnetic resonance imaging has been utilized as a powerful imaging modality to evaluate the structure and function of various organs in the human body,such as the brain. Additionally, diffusion and perfusion MR…
Many of the most important processes in cells take place on and across membranes. With the rise of an impressive array of powerful quantitative methods for characterizing these membranes, it is an opportune time to reflect on the structure…