Related papers: Myelin and saltatory conduction
In MRI, researchers have long endeavored to effectively visualize myelin distribution in the brain, a pursuit with significant implications for both scientific research and clinical applications. Over time, various methods such as myelin…
Mounting evidence shows that oscillatory activity is widespread in cell signaling. Here we review some of this recent evidence, focusing on both the molecular mechanisms that potentially underlie such dynamical behavior, and the potential…
Cell migration is a fundamental process for life and is highly dependent on the dynamical and mechanical properties of the cytoskeleton. Intensive physical and biochemical crosstalk between actin, microtubules, and intermediate filaments…
Rotational migration is one specific form of collective cell migration when epithelial cells are confined in a spherical geometry, such as in the epithelial acini. This tissue-level rotation motion is crucial for the morphogenesis of…
A new neural circuit is proposed by considering the myelin as an inductor. This new neural circuit can explain why the lump-parameter circuit used in previous C-P theory is valid. Meanwhile, it provides a new explanation of the biological…
Synchronization of activity among myocytes constituting vital organs, e.g., the heart, is crucial for physiological functions. Self-organized coordination in such heterogeneous ensemble of excitable and oscillatory cells is therefore of…
Brain-mapping techniques have proven to be vital in understanding the molecular, cellular, and functional mechanisms of the brain. Normal anatomical imaging can provide structural information on certain abnormalities in the brain. However…
Redundancy is a ubiquitous property of the nervous system. This means that vastly different configurations of cellular and synaptic components can enable the same neural circuit functions. However, until recently very little brain disorder…
Mammalian cell polarization and motility are important processes involved in many physiological and pathological phenomena, such as embryonic development, wound healing, and cancer metastasis. The traditional view of mammalian cell motility…
Despite great progress in neuroscience, there are still fundamental unanswered questions about the brain, including the origin of subjective experience and consciousness. Some answers might rely on new physical mechanisms. Given that…
Today, the human brain can be studied as a whole. Electroencephalography, magnetoencephalography, or functional magnetic resonance imaging techniques provide functional connectivity patterns between different brain areas, and during…
This paper worked towards modeling blood platelets. Blood platelets, also known as thrombocytes, play a key role in blood clotting which is a vital human function. Furthermore, the role of these entities in strokes, myocardial infarctions,…
Identification and manipulation of different GABAergic interneuron classes in the behaving animal are important to understand their role in circuit dynamics and behavior. The combination of optogenetics and large-scale neuronal recordings…
Motile cilia are a striking example of functional cellular organelle, conserved across all the eukaryotic species. Motile cilia allow swimming of cells and small organisms and transport of liquids across epithelial tissues. Whilst the…
Cranial lymphatic vessels (LVs) are involved in transport of fluids, macromolecules and CNS immune responses. Little information about spinal LVs is available, because these delicate structures are embedded within vertebral tissues and…
The hypothalamus plays an important role in the regulation of the bodys metabolic state and behaviors related to survival. Despite its importance however, many questions exist regarding the intrinsic and extrinsic connections of the…
Amyloid fibrils are stable aggregates of misfolded proteins and polypeptides that are insoluble and resistant to protease activity. Abnormal formation of amyloid fibrils in vivo may lead to neurodegenerative disorders and other systemic…
The epidermis is a specialized epithelium that constitutes the outermost layer of the skin, and it provides a protective barrier against environmental assaults. Primarily consisting of multilayered keratinocytes, the epidermis is…
Lumens are cavities enclosed by polarized cells that are essential for organ function, from nutrient transport in the gut to gas exchange in the lungs. Defects in lumen formation are associated with severe diseases, including polycystic…
Recent cellular-level volumetric brain reconstructions have revealed high levels of anatomic complexity. Determining which structural aspects of the brain to focus on, especially when comparing with computational models and other organisms,…