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Many theoretical expressions of dissipation along non-equilibrium processes have been proposed. However, they have not been fully verified by experiments. Especially for systems strongly interacting with environments the connection between…

Statistical Mechanics · Physics 2019-12-03 Ketan Goyal , Xian He , Ryoichi Kawai

Living and non-living active matter consumes energy at the microscopic scale to drive emergent, macroscopic behavior including traveling waves and coherent oscillations. Recent work has characterized non-equilibrium systems by their total…

Statistical Mechanics · Physics 2021-01-22 Daniel S. Seara , Benjamin B. Machta , Michael P. Murrell

Biomolecular machines consume free energy to break symmetry and make directed progress. Nonequilibrium ATP concentrations are the typical free energy source, with one cycle of a molecular machine consuming a certain number of ATP, providing…

Statistical Mechanics · Physics 2017-10-23 Aidan I Brown , David A Sivak

Nonequilibrium processes break time-reversal symmetry and generate entropy. Living systems are driven out-of-equilibrium at the microscopic level of molecular motors that exploit chemical potential gradients to transduce free energy to…

Statistical Mechanics · Physics 2022-12-06 Eden Nitzan , Aishani Ghosal , Gili Bisker

The principle of entropy increase is not only the basis of statistical mechanics, but also closely related to the irreversibility of time, the origin of life, chaos and turbulence. In this paper, we first discuss the dynamic system…

Statistical Mechanics · Physics 2022-10-11 Zou Dan Dan

The energy dissipated by a living organism is commonly identified with heat generation. However, as cells exchange metabolites with their environment they also dissipate energy in the form of chemical entropy. How dissipation is distributed…

Other Quantitative Biology · Quantitative Biology 2025-10-09 Tommaso Cossetto , Jonathan Rodenfels , Pablo Sartori

Characterizing the efficiency of movements is important for a better management of the cities. More specifically, the connection between the efficiency and uncertainty (entropy) production of a transport process is not established yet. In…

Physics and Society · Physics 2021-05-13 Indaco Biazzo , Mohsen Ghasemi Nezhadhaghighi , Abolfazl Ramezanpour

The entropy production in dissipative processes is the essence of the arrow of time and the second law of thermodynamics. For dissipation of quantum systems, it was recently shown that the entropy production contains indeed two…

Quantum Physics · Physics 2020-10-28 Camille L. Latune , Ilya Sinayskiy , Francesco Petruccione

One of the main issues that real energy converters present, when they produce effective work, is the inevitable entropy production. Within the context of Non-equilibrium Thermodynamics, entropy production tends to energetically degrade…

Statistical Mechanics · Physics 2024-01-08 L. A. Arias-Hernandez , G. Valencia-Ortega , F. Angulo-Brown , C. R. Martinez-Garcia

The metriplectic formalism is useful for describing complete dynamical systems which conserve energy and produce entropy. This creates challenges for model reduction, as the elimination of high-frequency information will generally not…

Numerical Analysis · Mathematics 2022-12-28 Anthony Gruber , Max Gunzburger , Lili Ju , Zhu Wang

Living systems operate far from thermodynamic equilibrium. Enzymatic activity can induce broken detailed balance at the molecular scale. This molecular scale breaking of detailed balance is crucial to achieve biological functions such as…

Biological Physics · Physics 2018-05-02 F. Gnesotto , F. Mura , J. Gladrow , C. P. Broedersz

The limit of small entropy production is reached in relaxing systems long after preparation, and in stationary driven systems in the limit of small driving power. Surprisingly, for extended systems this limit is not in general the…

Condensed Matter · Physics 2009-10-31 Leticia F. Cugliandolo , Jorge Kurchan

In order to respond to environmental signals, cells often use small molecular circuits to transmit information about their surroundings. Recently, motivated by concrete examples in signaling and gene regulation, a body of work has focused…

Molecular Networks · Quantitative Biology 2020-01-08 P. Szymańska-Rożek , D. Villamaina , J. Miȩkisz , A. M. Walczak

The entropy production rate is a key quantity in irreversible thermodynamics. In this work, we concentrate on the realization of entropy production rate in chemical reaction systems in terms of the experimentally measurable reaction rate.…

Chemical Physics · Physics 2019-11-14 Kinshuk Banerjee , Kamal Bhattacharyya

Biological activities are often seen entrained onto the day-night and other celestial mechanical cycles (e.g., seasonal and lunar), but studies on the origin of life have largely not accounted for such periodic external environmental…

Chaotic Dynamics · Physics 2024-08-21 Fan Zhang

We propose a housekeeping/excess decomposition of entropy production for general nonlinear dynamics in a discrete space, including chemical reaction networks and discrete stochastic systems. We exploit the geometric structure of…

Statistical Mechanics · Physics 2023-01-19 Kohei Yoshimura , Artemy Kolchinsky , Andreas Dechant , Sosuke Ito

When constructing models of the world, we aim for optimal compressions: models that include as few details as possible while remaining as accurate as possible. But which details -- or features measured in data -- should we choose to include…

Quantitative Methods · Quantitative Biology 2025-05-06 David P. Carcamo , Nicholas J. Weaver , Purushottam D. Dixit , Christopher W. Lynn

The interrelationships of the fundamental biological processes natural selection, mutation, and stochastic drift are quantified by the entropy rate of Moran processes with mutation, measuring the long-run variation of a Markov process. The…

Dynamical Systems · Mathematics 2014-01-14 Marc Harper

Living systems break detailed balance at small scales, consuming energy and producing entropy in the environment in order to perform molecular and cellular functions. However, it remains unclear how broken detailed balance manifests at…

Living systems produce "persistent" copies of information-carrying polymers, in which template and copy sequences remain correlated after physically decoupling. We identify a general measure of the thermodynamic efficiency with which these…

Statistical Mechanics · Physics 2022-06-08 Jenny Poulton , Pieter Rein ten Wolde , Thomas E Ouldridge