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Endothelial cells are responsible for the formation of the capillary blood vessel network. We describe a system of endothelial cells by means of two-dimensional molecular dynamics simulations of point-like particles. Cells' motion is…

Soft Condensed Matter · Physics 2022-12-22 Paolo Buttà , Fiammetta Cerreti , Vito D. P. Servedio , Livio Triolo

Most types of retinal neurons are spatially positioned in non-random patterns, termed retinal mosaics. Several developmental mechanisms are thought to be important in the formation of these mosaics. Most evidence to date suggests that…

Neurons and Cognition · Quantitative Biology 2012-08-07 Stephen J. Eglen , James C. T. Wong

Fluorescence microscopy has led to impressive quantitative models and new insights gained from richer sets of biomedical imagery. However, there is a dearth of rigorous and established bioimaging strategies for modeling spatiotemporal…

Subcellular Processes · Quantitative Biology 2019-05-01 Andrew Durden

Intracellular transport processes driven by molecular motors can be described by stochastic lattice models of self-driven particles. Here we focus on bidirectional transport models excluding the exchange of particles on the same track. We…

Biological Physics · Physics 2015-05-27 M. Ebbinghaus , C. Appert-Rolland , L. Santen

Molecular communication is a biologically-inspired method of communication with attractive properties for microscale and nanoscale devices. In molecular communication, messages are transmitted by releasing a pattern of molecules at a…

Information Theory · Computer Science 2008-12-09 Andrew W. Eckford

The spatial distribution of neuronal cells is an important requirement for achieving proper neuronal function in several parts of the nervous system of most animals. For instance, specific distribution of photoreceptors and related neuronal…

Neurons and Cognition · Quantitative Biology 2007-09-19 Luciano da Fontoura Costa , Fernando Rocha , Silene Maria Araujo de Lima

Cell shape is determined by a balance of intrinsic properties of the cell as well as its mechanochemical environment. Inhomogeneous shape changes underly many morphogenetic events and involve spatial gradients in active cellular forces…

Biological Physics · Physics 2018-04-04 Kinjal Dasbiswas , Edouard Hannezo , Nir. S. Gov

The propagation of signalling molecules within cellular networks is affected by network topology, but also by the spatial arrangement of cells in the networks. Understanding the collective reaction--diffusion behaviour in space of signals…

Disordered Systems and Neural Networks · Physics 2025-01-09 Adel Mehrpooya , Vivien J. Challis , Pascal R. Buenzli

Stochastic orders are binary relations defined on probability distributions which capture intuitive notions like being larger or being more variable. This paper introduces stochastic ordering of interference distributions in large-scale…

Information Theory · Computer Science 2012-10-26 Junghoon Lee , Cihan Tepedelenlioglu

Throughout developmental biology and ecology, transport can be driven by nonlocal interactions. Examples include cells that migrate based on contact with pseudopodia extended from other cells, and animals that move based on their vision of…

Pattern Formation and Solitons · Physics 2023-07-07 Thomas Jun Jewell , Andrew L. Krause , Philip K. Maini , Eamonn A. Gaffney

From social networks to Internet applications, a wide variety of electronic communication tools are producing streams of graph data; where the nodes represent users and the edges represent the contacts between them over time. This has led…

Social and Information Networks · Computer Science 2014-03-18 Nesreen K. Ahmed , Christopher Cole , Jennifer Neville

The importance of individual cells in a developing multicellular organism is well known but precisely how the individual cellular characteristics of those cells collectively drive the emergence of robust, homeostatic structures is less well…

Tissues and Organs · Quantitative Biology 2017-02-20 Philip Gerlee , David Basanta , Alexander R. A. Anderson

The structural properties of packed soft-core particles provide a platform to understand the cross-pollinated physical concepts in solid-state- and soft-matter physics. Confined on spherical surface, the traditional differential geometry…

Soft Condensed Matter · Physics 2025-01-06 Han Xie , Wenyu Liu , Zhenyue Lu , Jeff Z. Y. Chen , Yao Li

We study the statistical properties of a cellular automata model of traffic flow with the look-ahead potential. The model defines stochastic rules for the movement of cars on a lattice. We analyze the underlying statistical assumptions…

Probability · Mathematics 2012-09-27 Cory Hauck , Yi Sun , Ilya Timofeyev

Chemotaxis receptors in E. coli form clusters at the cell poles and also laterally along the cell body, and this clustering plays an important role in signal transduction. Recently, experiments using flourrescence imaging have shown that,…

Statistical Mechanics · Physics 2008-11-29 Hui Wang , Ned S. Wingreen , Ranjan Mukhopadhyay

Biological neural systems encode and transmit information as patterns of activity tracing complex trajectories in high-dimensional state-spaces, inspiring alternative paradigms of information processing. Heteroclinic networks, naturally…

Neurons and Cognition · Quantitative Biology 2021-10-26 Giovanni Sirio Carmantini , Fabio Schittler Neves , Marc Timme , Serafim Rodrigues

A common metaphor for describing development is a rugged "epigenetic landscape" where cell fates are represented as attracting valleys resulting from a complex regulatory network. Here, we introduce a framework for explicitly constructing…

Molecular Networks · Quantitative Biology 2014-09-11 Alex H. Lang , Hu Li , James J. Collins , Pankaj Mehta

Self-organization is a fundamental process of complex biological systems, particularly during the early stages of development. In the mammalian embryo, blastocyst formation exemplifies a self-organized system, involving the correct…

Quantitative Methods · Quantitative Biology 2025-05-30 Michael A. Ramirez-Sierra , Thomas R. Sokolowski

Stochasticity is a defining feature of the pairwise forces governing interactions in biological systems-from molecular motors to cell-cell adhesion-yet its consequences on large-scale dynamics remain poorly understood. Here, we show that…

Soft Condensed Matter · Physics 2025-08-27 Henry Alston , Raphael Voituriez , Thibault Bertrand

We present studies for an individual based model of three interacting populations whose individuals are mobile in a 2D-lattice. We focus on the pattern formation in the spatial distributions of the populations. Also relevant is the…

Populations and Evolution · Quantitative Biology 2007-12-18 I. C. Charret , M. V. Carneiro