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Lattice molecule models are proposed in order to study statistical mechanics of glass transition in finite dimensions. Molecules in the models are represented by hard Wang tiles and their density is controlled by a chemical potential. An…

Statistical Mechanics · Physics 2015-05-28 Shin-ichi Sasa

Information has intrinsic geometric and topological structure, arising from relative relationships beyond absolute values or types. For instance, the fact that two people share a meal describes a relationship independent of the meal's…

Combinatorics · Mathematics 2017-12-13 Michael Erdmann

Cell fate decisions emerge as a consequence of a complex set of gene regulatory networks. Models of these networks are known to have more parameters than data can determine. Recent work, inspired by Waddington's metaphor of a landscape, has…

Quantitative Methods · Quantitative Biology 2023-05-08 Archishman Raju , Eric D. Siggia

Consider the finite state graph that results from a simple, discrete, dynamical system in which an agent moves in a rectangular grid picking up and dropping packages. Can the state variables of the problem, namely, the agent location and…

Artificial Intelligence · Computer Science 2022-07-13 Blai Bonet , Hector Geffner

We present a new microscopic model of granular medium to study the role of dynamical correlations and the onset of spatial order induced by the inelasticity of the interactions. In spite of its simplicity, it features several different…

Statistical Mechanics · Physics 2009-11-07 A. Baldassarri , U. Marini Bettolo Marconi , A. Puglisi

Recent research has provided a wealth of evidence highlighting the pivotal role of high-order interdependencies in supporting the information-processing capabilities of distributed complex systems. These findings may suggest that high-order…

Adaptation and Self-Organizing Systems · Physics 2023-05-24 Patricio Orio , Pedro A. M. Mediano , Fernando E. Rosas

Complex systems are often driven by higher-order interactions among multiple units, naturally represented as hypergraphs. Understanding dependency structures within these hypergraphs is crucial for understanding and predicting the behavior…

Social and Information Networks · Computer Science 2025-05-29 John Hood , Caterina De Bacco , Aaron Schein

Living systems contain intricate biochemical networks whose structure is closely related to their function and allows them to exhibit robust behavior in the presence of external stimuli. Such networks typically involve catalytic enzymes,…

Biological Physics · Physics 2025-10-27 Vincent Ouazan-Reboul , Ramin Golestanian , Jaime Agudo-Canalejo

Cell shape has long been used to discern cell phenotypes and states, but the underlying premise has not been quantitatively tested. Here, we show that a single cell image can be used to discriminate its migration behavior by analyzing a…

Cell Behavior · Quantitative Biology 2023-09-29 Xiuxiu He , Kuangcai Chen , Ning Fang , Yi Jiang

We study the signalling structure of higher order quantum maps from an order-theoretic perspective, building on the combinatorial characterization of higher order types by Bisio and Perinotti. We have shown in a previous work…

Quantum Physics · Physics 2026-04-13 Anna Jenčová

Communication between cells is realized by exchange of biochemical substances. Due to internal organization of living systems and variability of external parameters, the exchange is heavily influenced by perturbations of various parameters…

Chaotic Dynamics · Physics 2015-05-19 Dragutin T. Mihailovic , Igor Balaz

Spatially annotated single-cell datasets provide unprecedented opportunities to dissect cell-cell communication in development and disease. Heterotypic signaling includes interactions between different cell types and is well established in…

Genomics · Quantitative Biology 2023-03-03 Fabian V. Filipp

Intracellular transport processes are essential to the healthy development of many organisms as well as more generally to healthy cellular function. The complex dynamics and interactions between protein molecules and filaments on different…

Dynamical Systems · Mathematics 2022-07-27 Maria-Veronica Ciocanel

In agricultural landscapes, the composition and spatial configuration of cultivated and semi-natural elements strongly impact species dynamics, their interactions and habitat connectivity. To allow for landscape structural analysis and…

Populations and Evolution · Quantitative Biology 2020-03-05 Patrizia Zamberletti , Julien Papaïx , Edith Gabriel , Thomas Opitz

Plants and insects communicate using chemical signals like volatile organic compounds (VOCs). A plant encodes information using different blends of VOCs, which propagate through the air to represent different symbolic information. This…

Information Theory · Computer Science 2026-02-10 Bitop Maitra , Murat Kuscu , Ozgur B. Akan

The dynamics of an extended, spatiotemporally chaotic system might appear extremely complex. Nevertheless, the local dynamics, observed through a finite spatiotemporal window, can often be thought of as a visitation sequence of a finite…

Chaotic Dynamics · Physics 2020-11-19 Boris Gutkin , Li Han , Rana Jafari , Adrien K. Saremi , Predrag Cvitanović

Polarity fields are known to exhibit long distance patterns, in both physical and biological systems. The mechanisms behind such patterns are poorly understood. Here, we describe the dynamics of polarity fields using an original physical…

Biological Physics · Physics 2019-07-24 Maryam Aliee , Arezki Boudaoud

Cell invasion and spatial pattern formation are two distinct manifestations of cellular self-organisation in development, regeneration, and disease. Here, we develop and analyse a unified theoretical framework that links these two seemingly…

Tissues and Organs · Quantitative Biology 2026-04-30 Carles Falcó , Samuel W. S. Johnson , Mohit P. Dalwadi , Philip K. Maini

Adaptive control in biological systems, such as intestinal immunity, remains poorly understood despite detailed knowledge of underlying regulatory networks. We propose an alternative framework based on stochastic martingale turnover, in…

Adaptation and Self-Organizing Systems · Physics 2026-05-01 Tomoyuki Yamaguchi

Complex systems with global interactions tend to be stable if interactions between components are sufficiently homogeneous. In biological systems, which often have small copy numbers and interactions mediated by diffusing agents, noise and…

Biological Physics · Physics 2023-04-14 Fabrizio Olmeda , Steffen Rulands