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We study a system of nonlinear differential equations simulating transport phenomena in active media. The model we are interested in is a generalization of the celebrated FitzHugh-Nagumo system, describing the nerve impulse propagation in…

Pattern Formation and Solitons · Physics 2019-05-07 Aleksandra Gawlik , Vsevolod Vladimirov , Sergii Skurativskyi

This paper is devoted to pulse solutions in FitzHugh--Nagumo systems that are coupled parabolic equations with rapidly periodically oscillating coefficients. In the limit of vanishing periods, there arises a two-scale FitzHugh--Nagumo…

Dynamical Systems · Mathematics 2017-07-27 Pavel Gurevich , Sina Reichelt

Since Noble adapted in 1962 the model of Hodgkin and Huxley to fit Purkinje fibres the refinement of models for cardiomyocytes has continued. Most of these models are high-dimensional systems of coupled equations so that the possible…

Dynamical Systems · Mathematics 2020-12-03 Maria Elena Gonzalez Herrero , Christian Kuehn , Krasimira Tsaneva-Atanasova

Understanding how external stimuli propagate in neural systems is an important challenge in the fields of neuroscience and nonlinear dynamics. Despite extensive studies over several decades, this problem remains poorly understood. In this…

Neurons and Cognition · Quantitative Biology 2025-03-13 L. Messee Goulefack , C. Masoller , R. Yamapi , C. Anteneodo

Excitable media are ubiquitous in nature, and in such systems the local excitation tends to self-organize in traveling waves, or in rotating spiral-shaped patterns in two or three spatial dimensions. Examples include waves during a pandemic…

Dynamical Systems · Mathematics 2023-12-25 Marie Cloet , Louise Arno , Desmond Kabus , Joeri Van der Veken , Alexander V. Panfilov , Hans Dierckx

In this note, we attempt to find counterexamples to the conjecture that the ideal form of a knot, that which minimizes its contour length while respecting a no-overlap constraint, also minimizes the volume of the knot, as determined by its…

Geometric Topology · Mathematics 2021-11-17 Alexander R. Klotz

Excitable membranes are an important type of nonlinear dynamical system and their study can be used to provide a connection between physical and biological circuits. We discuss two models of excitable membranes important in cardiac and…

Biological Physics · Physics 2012-12-18 Jarrett L. Lancaster , Esther M. Leise , Edward H. Hellen

We use computer simulations to compare the dynamical behaviour of torus and even-twist knots in polymers under tension. The knots diffuse through a mechanism similar to reptation. Their friction coefficients grow linearly with average knot…

Soft Condensed Matter · Physics 2010-07-27 R. Matthews , A. A. Louis , J. M. Yeomans

The FitzHugh-Nagumo equation, which was derived as a simplification of the Hodgkin-Huxley model for nerve impulse propagation, has been extensively studied as a paradigmatic activator-inhibitor system. We consider the version of this system…

Dynamical Systems · Mathematics 2018-03-15 Paul Cornwell , Christopher K. R. T. Jones

We establish sharp nonlinear stability results for fronts that describe the creation of a periodic pattern through the invasion of an unstable state. The fronts we consider are critical, in the sense that they are expected to mediate…

Analysis of PDEs · Mathematics 2026-03-26 Montie Avery , Paul Carter , Björn de Rijk , Arnd Scheel

We study the dynamics and interaction of coaxial vortex rings in the FitzHugh-Nagumo excitable medium. We find that threading vortex rings with a vortex string results in significant qualitative differences in their evolution and…

Pattern Formation and Solitons · Physics 2018-01-10 Fabian Maucher , Paul Sutcliffe

We consider the long-time behavior of a population of mean-field oscillators modeling the activity of interacting excitable neurons in large population. Each neuron is represented by its voltage and recovery variables, which are solution to…

Probability · Mathematics 2019-06-24 Eric Luçon , Christophe Poquet

Propagation of pulses in myelinated fibers may be described by appropriate solutions of spatially discrete FitzHugh-Nagumo systems. In these systems, propagation failure may occur if either the coupling between nodes is not strong enough or…

Soft Condensed Matter · Physics 2009-03-08 A. Carpio , L. L. Bonilla

We study the interplay between traveling action potentials and spatial inhomogeneities in the FitzHugh-Nagumo model to investigate possible mechanisms for the occurrence of fibrillatory states in the atria of the heart. Different dynamical…

Biological Physics · Physics 2010-04-07 Claudia Lenk , Mario Einax , Philipp Maass

In this paper we study how randomly generated knots occupy a volume of space using topological methods. To this end, we consider the evolution of the first homology of an immersed metric neighbourhood of a knot's embedding for growing…

Geometric Topology · Mathematics 2021-08-09 Daniele Celoria , Barbara I. Mahler

We report on the geometry and mechanics of knotted stiff strings. We discuss both closed and open knots. Our two main results are: (i) Their equilibrium energy as well as the equilibrium tension for open knots depend on the type of knot as…

Soft Condensed Matter · Physics 2015-06-25 R. Gallotti , O. Pierre-Louis

Linearization around unstable travelling waves in excitable systems can be used to approximate strength-extent curves in the problem of initiation of excitation waves for a family of spatially confined perturbations to the rest state. This…

Pattern Formation and Solitons · Physics 2020-04-08 Christopher D. Marcotte , Vadim N. Biktashev

In gauge theories with an extended Higgs sector the classical equations of motion can have solutions that describe stable, closed finite energy vortices. Such vortices separate two disjoint Higgs vacua, with one of the vacua embedded in the…

High Energy Physics - Theory · Physics 2007-05-23 Antti J. Niemi , Kaupo Palo , Sami Virtanen

New results on the groundstate energy of tight, magnetic knots are presented. Magnetic knots are defined as tubular embeddings of the magnetic field in an ideal, perfectly conducting, incompressible fluid. An orthogonal, curvilinear…

Mathematical Physics · Physics 2015-05-13 Francesca Maggioni , Renzo L. Ricca

First time in six decades, uncountable infinite exact solutions of FitzHugh-Nagumo model with diffusion have been found. FitzHugh-Nagumo model is a nonlinear dynamical system applicable to neurosciences, chemical kinetics, cell division,…

Dynamical Systems · Mathematics 2024-07-24 Shahid Sultan Ali Ramji , Eddy Kwessi , Mujahid Abbas