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Automatic medical image segmentation plays a critical role in scientific research and medical care. Existing high-performance deep learning methods typically rely on large training datasets with high-quality manual annotations, which are…
Automated breast cancer detection via computer vision techniques is challenging due to the complex nature of breast tissue, the subtle appearance of cancerous lesions, and variations in breast density. Mainstream techniques primarily focus…
Screening mammography is an important front-line tool for the early detection of breast cancer, and some 39 million exams are conducted each year in the United States alone. Here, we describe a multi-scale convolutional neural network (CNN)…
Automatic identification of patients with luminal and non-luminal subtypes during a routine mammography screening can support clinicians in streamlining breast cancer therapy planning. Recent machine learning techniques have shown promising…
Mammographic image analysis requires accurate localisation of salient mammographic masses. In mammographic computer-aided diagnosis, mass or Region of Interest (ROI) is often marked by physicians and features are extracted from the marked…
Most of the current state-of-the-art methods for tumor segmentation are based on machine learning models trained on manually segmented images. This type of training data is particularly costly, as manual delineation of tumors is not only…
Medical images differ from natural images in significantly higher resolutions and smaller regions of interest. Because of these differences, neural network architectures that work well for natural images might not be applicable to medical…
Breast cancer is a significant global health issue, and the diagnosis of breast cancer through imaging remains challenging. Mammography images are characterized by extremely high resolution, while lesions often occupy only a small portion…
Breast cancer has long been a prominent cause of mortality among women. Diagnosis, therapy, and prognosis are now possible, thanks to the availability of RNA sequencing tools capable of recording gene expression data. Molecular subtyping…
We present a deep convolutional neural network for breast cancer screening exam classification, trained and evaluated on over 200,000 exams (over 1,000,000 images). Our network achieves an AUC of 0.895 in predicting whether there is a…
A key promise of AI applications in healthcare is in increasing access to quality medical care in under-served populations and emerging markets. However, deep learning models are often only trained on data from advantaged populations that…
Recently, pathological diagnosis has achieved superior performance by combining deep learning models with the multiple instance learning (MIL) framework using whole slide images (WSIs). However, the giga-pixeled nature of WSIs poses a great…
Multiple Instance Learning (MIL) is widely used in analyzing histopathological Whole Slide Images (WSIs). However, existing MIL methods do not explicitly model the data distribution, and instead they only learn a bag-level or instance-level…
Mammography remains the most prevalent imaging tool for early breast cancer screening. The language used to describe abnormalities in mammographic reports is based on the breast Imaging Reporting and Data System (BI-RADS). Assigning a…
One issue with computer based histopathology image analysis is that the size of the raw image is usually very large. Taking the raw image as input to the deep learning model would be computationally expensive while resizing the raw image to…
Multiple Instance Learning (MIL) is widely used in medical imaging classification to reduce the labeling effort. While only bag labels are available for training, one typically seeks predictions at both bag and instance levels…
In healthcare, it is essential to explain the decision-making process of machine learning models to establish the trustworthiness of clinicians. This paper introduces BI-RADS-Net, a novel explainable deep learning approach for cancer…
Multiple instance learning (MIL) is a key algorithm for classification of whole slide images (WSI). Histology WSIs can have billions of pixels, which create enormous computational and annotation challenges. Typically, such images are…
Automatic breast lesion detection and classification is an important task in computer-aided diagnosis, in which breast ultrasound (BUS) imaging is a common and frequently used screening tool. Recently, a number of deep learning-based…
Accurate segmentation of multiple organs of the head, neck, chest, and abdomen from medical images is an essential step in computer-aided diagnosis, surgical navigation, and radiation therapy. In the past few years, with a data-driven…