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Breast cancer is the most common invasive cancer in women, and the second main cause of death. Breast cancer screening is an efficient method to detect indeterminate breast lesions early. The common approaches of screening for women are…

Image and Video Processing · Electrical Eng. & Systems 2021-01-26 Yuliana Jiménez Gaona , María José Rodriguez-Alvarez , Hector Espinó Morató , Darwin Castillo Malla , Vasudevan Lakshminarayanan

Screening mammograms are a routine imaging exam performed to detect breast cancer in its early stages to reduce morbidity and mortality attributed to this disease. In order to maximize the efficacy of breast cancer screening programs,…

Image and Video Processing · Electrical Eng. & Systems 2020-09-30 Vikash Gupta , Clayton Taylor , Sarah Bonnet , Luciano M. Prevedello , Jeffrey Hawley , Richard D White , Mona G Flores , Barbaros Selnur Erdal

This work contributes to breast cancer sub-type classification using histopathological images. We utilize masked autoencoders (MAEs) to learn a self-supervised embedding tailored for computer vision tasks in this domain. This embedding…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Annalisa Chiocchetti , Marco Dossena , Christopher Irwin , Luigi Portinale

This paper explores the problem of breast tissue classification of microscopy images. Based on the predominant cancer type the goal is to classify images into four categories of normal, benign, in situ carcinoma, and invasive carcinoma.…

Computer Vision and Pattern Recognition · Computer Science 2018-06-29 Kamyar Nazeri , Azad Aminpour , Mehran Ebrahimi

Breast cancer is the second leading cause of cancer-related death after lung cancer in women. Early detection of breast cancer in X-ray mammography is believed to have effectively reduced the mortality rate. However, a relatively high false…

Image and Video Processing · Electrical Eng. & Systems 2021-02-16 Xuejiao Tang , Liuhua Zhang , Wenbin Zhang , Xin Huang , Vasileios Iosifidis , Zhen Liu , Mingli Zhang , Enza Messina , Ji Zhang

Multiple instance learning (MIL) stands as a powerful approach in weakly supervised learning, regularly employed in histological whole slide image (WSI) classification for detecting tumorous lesions. However, existing mainstream MIL methods…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Wenhui Zhu , Xiwen Chen , Peijie Qiu , Aristeidis Sotiras , Abolfazl Razi , Yalin Wang

Deep learning models have revolutionized the field of medical image analysis, due to their outstanding performances. However, they are sensitive to spurious correlations, often taking advantage of dataset bias to improve results for…

Computer Vision and Pattern Recognition · Computer Science 2024-05-06 Diogo J. Araújo , M. Rita Verdelho , Alceu Bissoto , Jacinto C. Nascimento , Carlos Santiago , Catarina Barata

Accurate characterization of suspicious breast lesions in mammography is important for early diagnosis and treatment planning. While Convolutional Neural Networks (CNNs) are effective at extracting local visual patterns, they are less…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Mohammed Asad , Mohit Bajpai , Sudhir Singh , Rahul Katarya

Weakly supervised instance labeling using only image-level labels, in lieu of expensive fine-grained pixel annotations, is crucial in several applications including medical image analysis. In contrast to conventional instance segmentation…

Computer Vision and Pattern Recognition · Computer Science 2019-07-31 Jayaraman J. Thiagarajan , Satyananda Kashyap , Alexandros Karagyris

Breast cancer is a highly heterogeneous disease with diverse molecular profiles. The PAM50 gene signature is widely recognized as a standard for classifying breast cancer into intrinsic subtypes, enabling more personalized treatment…

Some recent studies have described deep convolutional neural networks to diagnose breast cancer in mammograms with similar or even superior performance to that of human experts. One of the best techniques does two transfer learnings: the…

Image and Video Processing · Electrical Eng. & Systems 2022-08-04 Daniel G. P. Petrini , Carlos Shimizu , Rosimeire A. Roela , Gabriel V. Valente , Maria A. A. K. Folgueira , Hae Yong Kim

Convolutional neural networks (CNN) have achieved state of the art performance on both classification and segmentation tasks. Applying CNNs to microscopy images is challenging due to the lack of datasets labeled at the single cell level. We…

Computer Vision and Pattern Recognition · Computer Science 2017-05-25 Oren Z. Kraus , Lei Jimmy Ba , Brendan Frey

Fine-grained classification of whole slide images (WSIs) is essential in precision oncology, enabling precise cancer diagnosis and personalized treatment strategies. The core of this task involves distinguishing subtle morphological…

Computer Vision and Pattern Recognition · Computer Science 2025-04-07 Cheng Jin , Luyang Luo , Huangjing Lin , Jun Hou , Hao Chen

Accurate tumor segmentation and classification in breast ultrasound (BUS) imaging remain challenging due to low contrast, speckle noise, and diverse lesion morphology. This study presents a multi-task deep learning framework that jointly…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Samuel E. Johnny , Bernes L. Atabonfack , Israel Alagbe , Assane Gueye

Multiple Instance Learning (MIL) is a weakly-supervised problem in which one label is assigned to the whole bag of instances. An important class of MIL models is instance-based, where we first classify instances and then aggregate those…

Image and Video Processing · Electrical Eng. & Systems 2024-03-13 Łukasz Struski , Dawid Rymarczyk , Arkadiusz Lewicki , Robert Sabiniewicz , Jacek Tabor , Bartosz Zieliński

Malignant lymphoma subtype classification directly impacts treatment strategies and patient outcomes, necessitating classification models that achieve both high accuracy and sufficient explainability. This study proposes a novel explainable…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Daiki Nishiyama , Hiroaki Miyoshi , Noriaki Hashimoto , Koichi Ohshima , Hidekata Hontani , Ichiro Takeuchi , Jun Sakuma

Whole-slide image classification represents a key challenge in computational pathology and medicine. Attention-based multiple instance learning (MIL) has emerged as an effective approach for this problem. However, the effect of attention…

Quantitative Methods · Quantitative Biology 2025-03-14 Rajiv Krishnakumar , Julien Baglio , Frederik F. Flöther , Christian Ruiz , Stefan Habringer , Nicole H. Romano

We develop an end-to-end training algorithm for whole-image breast cancer diagnosis based on mammograms. It requires lesion annotations only at the first stage of training. After that, a whole image classifier can be trained using only…

Computer Vision and Pattern Recognition · Computer Science 2019-10-08 Li Shen

3D imaging enables accurate diagnosis by providing spatial information about organ anatomy. However, using 3D images to train AI models is computationally challenging because they consist of 10x or 100x more pixels than their 2D…

Breast cancer remains a global challenge, causing over 1 million deaths globally in 2018. To achieve earlier breast cancer detection, screening x-ray mammography is recommended by health organizations worldwide and has been estimated to…