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Multiple Instance Learning (MIL) involves predicting a single label for a bag of instances, given positive or negative labels at bag-level, without accessing to label for each instance in the training phase. Since a positive bag contains…

Machine Learning · Computer Science 2020-09-09 Beomjo Shin , Junsu Cho , Hwanjo Yu , Seungjin Choi

The quantification of biomarkers on immunohistochemistry breast cancer images is essential for defining appropriate therapy for breast cancer patients, as well as for extracting relevant information on disease prognosis. This is an arduous…

Image and Video Processing · Electrical Eng. & Systems 2023-11-27 Blanca Maria Priego-Torresa , Barbara Lobato-Delgado , Lidia Atienza-Cuevas , Daniel Sanchez-Morillo

Radiologists usually observe anatomical regions of chest X-ray images as well as the overall image before making a decision. However, most existing deep learning models only look at the entire X-ray image for classification, failing to…

Computer Vision and Pattern Recognition · Computer Science 2021-05-21 Nkechinyere N. Agu , Joy T. Wu , Hanqing Chao , Ismini Lourentzou , Arjun Sharma , Mehdi Moradi , Pingkun Yan , James Hendler

The progression of breast cancer can be quantified in lymph node whole-slide images (WSIs). We describe a novel method for effectively performing classification of whole-slide images and patient level breast cancer grading. Our method…

Computer Vision and Pattern Recognition · Computer Science 2017-07-25 Thomas Wollmann , Karl Rohr

A supervised diagnosis system for digital mammogram is developed. The diagnosis processes are done by transforming the data of the images into a feature vector using wavelets multilevel decomposition. This vector is used as the feature…

Image and Video Processing · Electrical Eng. & Systems 2020-03-09 Essam A. Rashed , and Mohamed G. Awad

Deep neural networks exhibit limited generalizability across images with different entangled domain features and categorical features. Learning generalizable features that can form universal categorical decision boundaries across domains is…

Computer Vision and Pattern Recognition · Computer Science 2021-04-07 Qingjie Meng , Jacqueline Matthew , Veronika A. Zimmer , Alberto Gomez , David F. A. Lloyd , Daniel Rueckert , Bernhard Kainz

The increased availability of X-ray image archives (e.g. the ChestX-ray14 dataset from the NIH Clinical Center) has triggered a growing interest in deep learning techniques. To provide better insight into the different approaches, and their…

Computer Vision and Pattern Recognition · Computer Science 2019-01-30 Ivo M. Baltruschat , Hannes Nickisch , Michael Grass , Tobias Knopp , Axel Saalbach

Breast cancer is considered as the most fatal type of cancer among women worldwide and it is crucially important to be diagnosed at its early stages. In the current study, we aim to represent a fast and efficient framework which consists of…

Computer Vision and Pattern Recognition · Computer Science 2019-05-13 Parvin Yousefikamal

Breast cancer has become a symbol of tremendous concern in the modern world, as it is one of the major causes of cancer mortality worldwide. In this regard, breast ultrasonography images are frequently utilized by doctors to diagnose breast…

Image and Video Processing · Electrical Eng. & Systems 2022-02-15 Muhammad Sakib Khan Inan , Fahim Irfan Alam , Rizwan Hasan

Deep learning models benefit from training with a large dataset (labeled or unlabeled). Following this motivation, we present an approach to learn a deep learning model for the automatic segmentation of Organs at Risk (OARs) in cervical…

Image and Video Processing · Electrical Eng. & Systems 2023-02-22 Monika Grewal , Dustin van Weersel , Henrike Westerveld , Peter A. N. Bosman , Tanja Alderliesten

The advent of deep learning has significantly propelled the capabilities of automated medical image diagnosis, providing valuable tools and resources in the realm of healthcare and medical diagnostics. This research delves into the…

Image and Video Processing · Electrical Eng. & Systems 2023-11-20 Ryan Donghan Kwon , Dohyun Lim , Yoonha Lee , Seung Won Lee

Purpose: To develop a deep network architecture that would achieve fully automated radiologist-level segmentation of cancers at breast MRI. Materials and Methods: In this retrospective study, 38229 examinations (composed of 64063 individual…

Multi-instance learning (MIL) deals with objects represented as bags of instances and can predict instance labels from bag-level supervision. However, significant performance gaps exist between instance-level MIL algorithms and supervised…

Machine Learning · Computer Science 2022-10-06 Weijia Zhang , Xuanhui Zhang , Han-Wen Deng , Min-Ling Zhang

Multi-Instance Learning (MIL) is pivotal for analyzing complex, weakly labeled datasets, such as whole-slide images (WSIs) in computational pathology, where bags comprise unordered collections of instances with sparse diagnostic relevance.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Yuedi Zhang , Zhixiang Xia , Guosheng Yin , Bin Liu

Mammogram image is important for breast cancer screening, and typically obtained in a dual-view form, i.e., cranio-caudal (CC) and mediolateral oblique (MLO), to provide complementary information. However, previous methods mostly learn…

Computer Vision and Pattern Recognition · Computer Science 2023-06-21 Zhiwei Wang , Junlin Xian , Kangyi Liu , Xin Li , Qiang Li , Xin Yang

Bag-based Multiple Instance Learning (MIL) approaches have emerged as the mainstream methodology for Whole Slide Image (WSI) classification. However, most existing methods adopt a segmented training strategy, which first extracts features…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Jiangping Wen , Jinyu Wen , Meie Fang

Breast cancer screening, primarily conducted through mammography, is often supplemented with ultrasound for women with dense breast tissue. However, existing deep learning models analyze each modality independently, missing opportunities to…

Image and Video Processing · Electrical Eng. & Systems 2023-11-16 Yiqiu Shen , Jungkyu Park , Frank Yeung , Eliana Goldberg , Laura Heacock , Farah Shamout , Krzysztof J. Geras

Imperfect labels limit the quality of predictions learned by deep neural networks. This is particularly relevant in medical image segmentation, where reference annotations are difficult to collect and vary significantly even across expert…

Computer Vision and Pattern Recognition · Computer Science 2021-07-07 Eugene Vorontsov , Samuel Kadoury

Multi-label classification of chest X-ray images is frequently performed using discriminative approaches, i.e. learning to map an image directly to its binary labels. Such approaches make it challenging to incorporate auxiliary information…

Artificial Intelligence · Computer Science 2021-03-11 Anjany Sekuboyina , Daniel Oñoro-Rubio , Jens Kleesiek , Brandon Malone

This study presents a deep learning system for breast cancer detection in mammography, developed using a modified EfficientNetV2 architecture with enhanced attention mechanisms. The model was trained on mammograms from a major Thai medical…

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