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One of the vital functions of naturally occurring cilia is fluid transport. Biological cilia use spatially asymmetric strokes to generate a net fluid flow that can be utilized for feeding, swimming, and other functions. Biomimetic synthetic…

Fluid Dynamics · Physics 2018-07-19 Srinivas Hanasoge , Peter J. Hesketh , Alexander Alexeev

Accurate and integrable control of different flows within microfluidic channels is crucial to further development of lab-on-a-chip and fully integrated adaptable structures. Here we introduce a flexible microactuator that buckles at a high…

Fluid Dynamics · Physics 2016-04-20 Behrouz Tavakol , Douglas P. Holmes

A model is presented for predicting the capture of magnetic micro/nano-particles in a bioseparation microsystem. This bioseparator consists of an array of conductive elements embedded beneath a rectangular microfluidic channel. The magnetic…

Biological Physics · Physics 2007-05-23 E. P. Furlani , Y. Sahoo , K. C. Ng , J. C. Wortman , T. E. Monk

Microfluidic channels are integral to biomedical technology and process engineering, offering versatility in handling fluids with complex properties, often a combination of viscous and elastic attributes. Despite significant advancements in…

Soft Condensed Matter · Physics 2025-09-29 Sampad Laha , Siddhartha Mukherjee , Suman Chakraborty

Microfluidic mixing is a fundamental functionality in most lab on a chip (LOC) systems,whereas realization of efficient mixing is challenging in microfluidic channels due to the small Reynolds numbers. Here, we design and fabricate a…

Applied Physics · Physics 2020-01-10 Wenbo Li , Wei Chu , Peng Wang , Jia Qi , Zhe Wang , Jintian Lin , Min Wang , Ya Cheng

Spatial separation of suspended particles based on contrast in their physical or chemical properties forms the basis of various biological assays performed on lab-on-achip devices. To electronically acquire this information, we have…

Emerging Technologies · Computer Science 2018-08-13 Ningquan Wang , Ruxiu Liu , Roozbeh Khodambashi , Norh Asmare , A. Fatih Sarioglu

Flows of particles through bottlenecks are ubiquitous in nature and industry, involving both dry granular materials and suspensions. However, practical limitations of conventional experimental setups hinder the full understanding of these…

Soft Condensed Matter · Physics 2025-07-02 Lars Kool , Jules Tampier , Philippe Bourrianne , Anke Lindner

Within microcentrifuge devices, a microfluidic vortex separates larger particles from a heterogeneous suspension using inertial migration, a phenomenon that causes particles to migrate across streamlines. The ability to selectively capture…

Fluid Dynamics · Physics 2023-03-14 Samuel Christensen , Marcus Roper

Biocomputing systems based on engineered bacteria can lead to novel tools for environmental monitoring and detection of metabolic diseases. In this paper, we propose a Bacterial Molecular Computing on a Chip (BMCoC) using microfluidic and…

We report the implementation of a fully on-chip, lensless microscopy technique termed optofluidic ptychography. This imaging modality complements the miniaturization provided by microfluidics and allows the integration of ptychographic…

Instrumentation and Detectors · Physics 2021-12-21 Pengming Song , Chengfei Guo , Shaowei Jiang , Tianbo Wang , Patrick Hu , Derek Hu , Zibang Zhang , Bin Feng , Guoan Zheng

The acoustofluidic method holds great promise for manipulating microorganisms. When exposed to the steady vortex structures of acoustic streaming flow, these microorganisms exhibit intriguing dynamic behaviors, such as hydrodynamic trapping…

Fluid Dynamics · Physics 2025-04-25 Xuyang Sun , Wenchang Tan , Yi Man

Effective mixing is essential for biochemical reactions. In droplet-based microfluidics, immediate mixing of substances upon contact in the droplet formation stage can greatly enhance the uniformity of chemical reactions. Furthermore, it…

Microfluidic chips have been fabricated to study electrokinetic pumping generated by a low voltage AC signal applied to an asymmetric electrode array. A measurement procedure has been established and followed carefully resulting in a high…

In the last years, it was demonstrated that neutral molecules can be loaded on a microchip directly from a supersonic beam. The molecules are confined in microscopic traps that can be moved smoothly over the surface of the chip. Once the…

Atomic Physics · Physics 2015-09-15 Gabriele Santambrogio

Particle-wall interactions play a crucially important role in various applications such as microfluidic devices for cell sorting, particle separation, entire class of hydrodynamic filtration and its derivatives, etc. Yet, accurate…

Fluid Dynamics · Physics 2025-03-18 Aryan Mehboudi , Shrawan Singhal , S. V. Sreenivasan

Droplet-based microfluidics has emerged as a powerful technology for the miniaturization and automation of biochemical assays. The replacement of surfactants by nanoparticles as interfacial stabilizers has gained increasing interest.…

Soft Condensed Matter · Physics 2019-06-21 Laura Andreina Chacon Orellana , Jean-Christophe Baret

Microfluidic technology provides a solution to the challenge of continuous CaCO$_3$ particle synthesis. In this study, we utilized a 3D-printed microfluidic chip to synthesize CaCO$_3$ micro and nanoparticles in vaterite form. Our primary…

We use pervaporation-based microfluidic devices to concentrate species in aqueous solutions with spatial and temporal control of the process. Using experiments and modelling, we quantitatively describe the advection-diffusion behavior of…

Soft Condensed Matter · Physics 2009-11-11 Jacques Leng , Barbara Lonetti , Patrick Tabeling , Mathieu Joanicot , Armand Ajdari

[First paragraph] In a recent paper Yamada et al. propose the novel concept of "pinched flow fractionation" (PFF) for the continuous size separation and analysis of particles in microfabricated lab-on-a-chip devices. In their description of…

Fluid Dynamics · Physics 2011-11-10 Niels Asger Mortensen

Recent works demonstrated that fiber arrays may constitue the basis of an open digital microfluidics. Various processes, such as droplet motion, fragmentation, trapping, release, mixing and encapsulation, may be achieved on fiber arrays.…

Fluid Dynamics · Physics 2015-03-13 Floriane Weyer , Marjorie Lismont , Laurent Dreesen , Nicolas Vandewalle