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Abstract: In our paper the new algorithm enhanced multi gradient Dilution Preparation (EMDP) is discussed. This new algorithm is reported with a lab on chip or digital Microfluidic biochip to operate multiple operation on a tiny chip. We…
Acoustically driven mixing of small fluid volumes is reported. Using surface acoustic waves on a mixer chip, conversion of those into bulk waves, and employing wave guiding effects enables us to distribute a set of "virtual sources" for…
Microfluidic channels with embedded ion permselective medium under the application of electric current are commonly used for electrokinetic processes as on-chip ion concentration polarization (ICP) and bioparticle preconcentration to…
We present an experimental investigation of the agglomeration of microbubbles into a 2D microfoam and its flow in a rectangular microchannel. Using a flow-focusing method, we produce the foam in situ on a microfluidic chip for a large range…
The design of microfluidic devices is a cumbersome and tedious process that can be significantly improved by simulation. Methods based on Computational Fluid Dynamics (CFD) are considered state-of-the-art, but require extensive compute time…
A novel method to pump fluid in lab on chip devices with velocities up to tens of micrometer per second is introduced. A focused laser beam locally heats up an electrolyte. A net charge tends to accumulate in the heat-absorbing area, due to…
In this work, we introduce the novel technique of in-chip drop on demand, which consists in dispensing picoliter to nanoliter drops on demand directly in the liquid-filled channels of a polymer microfluidic chip, at frequencies up to 2.5…
The present work was inspired by the recent developments in laboratory experiments made on chip, where culturing of multiple cell species was possible. The model is based on coupled reaction-diffusion-transport equations with chemotaxis,…
The main aim of this study is to find the best, most rapid, and the most accurate numerical method to find the liquid-gas interface of capillary driven flow during the time in circular Microchannels by using COMSOL Multiphysics software.…
Small volume fluid handling in single and multiphase microfluidics provides a promising strategy for efficient bio-chemical assays, low-cost point-of-care diagnostics and new approaches to scientific discoveries. However multiple barriers…
The micromixing process in microfluidic devices is of central importance in quite a few applications, with microfluidic studies on carbon capture and environmental monitoring being two examples. High surface area to volume ratio in…
Optofluidic devices have revolutionized the manipulation and transportation of fluid at smaller length scales ranging from micrometers to millimeters. We describe a dedicated optical setup for studying laser-induced cavitation inside a…
Engineering simple, artificial models of living cells allows synthetic biologists to study cellular functions under well-controlled conditions. Reconstituting multicellular behaviors with synthetic cell-mimics is still a challenge because…
Large-scale microfluidic microsystems with complex three-dimensional (3D) configurations are highly in demand by both fundamental research and industrial application, holding the potentials for fostering a wide range of innovative…
Fine-tuned ion transport across nanoscale pores is key to many biological processes such as neurotransmission. Recent advances have enabled the confinement of water and ions to two dimensions, unveiling transport properties unreachable at…
The ability to induce regions of high and low ionic concentration adjacent to a permeselective membrane or nanochannel subject to an externally applied electric field (a phenomenon termed concentration-polarization) has been used for a…
Droplet-based microfluidic systems are a promising platform forlab-on-a-chip (LoC) applications. These systems can also be used toenhance LoC applications with integrated droplet control information or for data transmission scenarios in the…
Clogging of microchannels due to particle adhesion on the walls is a serious problem in many industrial processes. As such, the service life of microfluidic systems is determined by their ability to maintain flow without interruption over a…
We study compressible fluid flow in narrow two-dimensional channels using a novel molecular dynamics simulation method. In the simulation area, an upstream source is maintained at constant density and temperature while a downstream…
Lab-on-a-chip (LOC) forms the basis of the new-generation portable analytical systems. LOC allows the manipulation of ultralow flows of liquid reagents and multistep reactions on a microfluidic chip, which requires a robust and precise…