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We present Bionic Tracking, a novel method for solving biological cell tracking problems with eye tracking in virtual reality using commodity hardware. Using gaze data, and especially smooth pursuit eye movements, we are able to track cells…

Human-Computer Interaction · Computer Science 2020-08-04 Ulrik Günther , Kyle I. S. Harrington , Raimund Dachselt , Ivo F. Sbalzarini

Tracking-by-detection approaches are some of the most successful object trackers in recent years. Their success is largely determined by the detector model they learn initially and then update over time. However, under challenging…

Computer Vision and Pattern Recognition · Computer Science 2015-10-01 Yang Hua , Karteek Alahari , Cordelia Schmid

This paper introduces a novel framework for the automated tracking of cells, with a particular focus on the challenging situation of phase contrast microscopic videos. Our framework is based on a topology preserving variational segmentation…

Quantitative Methods · Quantitative Biology 2012-03-28 Michael Moeller , Martin Burger , Peter Dieterich , Albrecht Schwab

Conventional multi-stage cell tracking approaches rely heavily on detection or segmentation in each frame as a prerequisite, requiring substantial resources for high-quality segmentation masks and increasing the overall prediction time. To…

Image and Video Processing · Electrical Eng. & Systems 2025-10-14 Yaxuan Song , Jianan Fan , Heng Huang , Mei Chen , Weidong Cai

In this work we propose an approach to select the classification method and features, based on the state-of-the-art, with best performance for diagnostic support through peripheral blood smear images of red blood cells. In our case we used…

Machine Learning · Computer Science 2020-10-12 Nataša Petrović , Gabriel Moyà-Alcover , Antoni Jaume-i-Capó , Manuel González-Hidalgo

Microscopy images from different imaging conditions, organs, and tissues often have numerous cells with various shapes on a range of backgrounds. As a result, designing a deep learning model to count cells in a source domain becomes…

Computer Vision and Pattern Recognition · Computer Science 2023-03-21 Zuhui Wang

Tracking cells in 3D at high speed continues to attract extensive attention for many biomedical applications, such as monitoring immune cell migration and observing tumor metastasis in flowing blood vessels. Here, we propose a deep…

Optics · Physics 2018-05-16 Kan Liu , Hui Qiao , Jiamin Wu , Haoqian Wang , Lu Fang , Qionghai Dai

Lineage tracing, the determination and mapping of progeny arising from single cells, is an important approach enabling the elucidation of mechanisms underlying diverse biological processes ranging from development to disease. We developed a…

Our work targets automated analysis to quantify the growth dynamics of a population of bacilliform bacteria. We propose an innovative approach to frame-sequence tracking of deformable-cell motion by the automated minimization of a new,…

Computer Vision and Pattern Recognition · Computer Science 2022-07-12 Sorena Sarmadi , James J. Winkle , Razan N. Alnahhas , Matthew R. Bennett , Krešimir Josić , Andreas Mang , Robert Azencott

Matching cells over time has long been the most difficult step in cell tracking. In this paper, we approach this problem by recasting it as a classification problem. We construct a feature set for each cell, and compute a feature difference…

Computer Vision and Pattern Recognition · Computer Science 2017-11-01 Quan Wang , Yan Ou , A. Agung Julius , Kim L. Boyer , Min Jun Kim

Tracking the development of living cells in live-cell time-lapses reveals crucial insights into single-cell behavior and presents tremendous potential for biomedical and biotechnological applications. In microbial live-cell imaging (MLCI),…

Computer Vision and Pattern Recognition · Computer Science 2024-11-04 J. Seiffarth , L. Blöbaum , R. D. Paul , N. Friederich , A. J. Yamachui Sitcheu , R. Mikut , H. Scharr , A. Grünberger , K. Nöh

Accurate segmentation of 3-D cell nuclei in microscopy images is essential for the study of nuclear organization, gene expression, and cell morphodynamics. Current image segmentation methods are challenged by the complexity and variability…

Image and Video Processing · Electrical Eng. & Systems 2022-03-18 Sundaresh Ram , Jeffrey J. Rodriguez

We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Fidel A. Guerrero-Peña , Pedro D. Marrero Fernandez , Tsang Ing Ren , Alexandre Cunha

Recent advances in bioimaging have provided scientists a superior high spatial-temporal resolution to observe dynamics of living cells as 3D volumetric videos. Unfortunately, the 3D biomedical video analysis is lagging, impeded by resource…

Computer Vision and Pattern Recognition · Computer Science 2021-06-23 Mengyang Zhao , Quan Liu , Aadarsh Jha , Ruining Deng , Tianyuan Yao , Anita Mahadevan-Jansen , Matthew J. Tyska , Bryan A. Millis , Yuankai Huo

We present a new annotated microscopic cellular image dataset to improve the effectiveness of machine learning methods for cellular image analysis. Cell counting is an important step in cell analysis. Typically, domain experts manually…

Image and Video Processing · Electrical Eng. & Systems 2024-11-20 Abdurahman Ali Mohammed , Catherine Fonder , Donald S. Sakaguchi , Wallapak Tavanapong , Surya K. Mallapragada , Azeez Idris

For over two decades, image-based profiling has revolutionized cell phenotype analysis. Image-based profiling processes rich, high-throughput, microscopy data into thousands of unbiased measurements that reveal phenotypic patterns powerful…

We study the problem of instance segmentation in biological images with crowded and compact cells. We formulate this task as an integer program where variables correspond to cells and constraints enforce that cells do not overlap. To solve…

Computer Vision and Pattern Recognition · Computer Science 2017-09-22 Chong Zhang , Shaofei Wang , Miguel A. Gonzalez-Ballester , Julian Yarkony

Visual tracking is typically solved as a discriminative learning problem that usually requires high-quality samples for online model adaptation. It is a critical and challenging problem to evaluate the training samples collected from…

Computer Vision and Pattern Recognition · Computer Science 2020-04-02 Weichao Li , Xi Li , Omar Elfarouk Bourahla , Fuxian Huang , Fei Wu , Wei Liu , Zhiheng Wang , Hongmin Liu

With the advance of fluorescence imaging technologies, recently cell biologists are able to record the movement of protein vesicles within a living cell. Automatic tracking of the movements of these vesicles become key for qualitative…

Quantitative Methods · Quantitative Biology 2015-06-09 Min Xu

Cells count become a challenging problem when the cells move in a continuous stream, and their boundaries are difficult for visual detection. To resolve this problem we modified the training and decision making processes using curriculum…

Computer Vision and Pattern Recognition · Computer Science 2024-04-17 Danil Afonchikov , Elena Kornaeva , Irina Makovik , Alexey Kornaev