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A novel computational, non-iterative and noise-robust reconstruction method is introduced for the planar anisotropic inverse conductivity problem. The method is based on bypassing the unstable step of the reconstruction of the values of the…

Analysis of PDEs · Mathematics 2015-06-25 Sarah Jane Hamilton , Matti Lassas , Samuli Siltanen

Atmospheric tomography, the problem of reconstructing atmospheric turbulence profiles from wavefront sensor measurements, is an integral part of many adaptive optics systems used for enhancing the image quality of ground-based telescopes.…

Numerical Analysis · Mathematics 2025-02-06 Lukas Weissinger , Simon Hubmer , Bernadett Stadler , Ronny Ramlau

In this paper we consider the inverse acoustic scattering (in \mathbb{R}^3) or electromagnetic scattering (in \mathbb{R}^2, for the scalar TE-polarization case) problem of reconstructing possibly multiple defective penetrable regions in a…

Analysis of PDEs · Mathematics 2015-10-08 Fioralba Cakoni , Isaac Harris

The computational pipelines of single-particle cryo-electron microscopy (cryo-EM) and cryo-electron tomography (cryo-ET) include an early particle-picking stage, in which a micrograph or tomogram is scanned to extract candidate particles,…

Signal Processing · Electrical Eng. & Systems 2026-04-14 Amnon Balanov , Alon Zabatani , Tamir Bendory

Cryogenic electron microscopy is widely used in structural biology, but its resolution is often limited by the dynamics of the macromolecule. Here, we developed a refinement protocol based on Gaussian mixture models that integrates particle…

Quantitative Methods · Quantitative Biology 2023-08-31 Muyuan Chen , Michael F. Schmid , Wah Chiu

Cryogenic electron microscopy (cryo-EM) is an invaluable technique for determining high-resolution three-dimensional structures of biological macromolecules using transmission particle images. The inherent symmetry in these macromolecules…

Optimization and Control · Mathematics 2024-11-06 Qi Zhang , Chenglong Bao , Hai Lin , Mingxu Hu

Cryo-electron tomography enables 3D visualization of cells in a near native state at molecular resolution. The produced cellular tomograms contain detailed information about all macromolecular complexes, their structures, their abundances…

Quantitative Methods · Quantitative Biology 2019-04-30 Min Xu , Elitza I Tocheva , Yi-Wei Chang , Grant J Jensen , Frank Alber

The three-dimensional structure of proteins plays a crucial role in determining their function. Protein structure prediction methods, like AlphaFold, offer rapid access to a protein structure. However, large protein complexes cannot be…

Biomolecules · Quantitative Biology 2025-03-05 Gabriel Ducrocq , Lukas Grunewald , Sebastian Westenhoff , Fredrik Lindsten

Scanning tunnelling microscopy (STM) is a powerful technique for imaging surfaces with atomic resolution, providing insight into physical and chemical processes at the level of single atoms and molecules. A regular task of STM image…

We generalize the previous study on the application of variational autoencoders to the two-dimensional Ising model to a system with anisotropy. Due to the self-duality property of the system, the critical points can be located exactly for…

Disordered Systems and Neural Networks · Physics 2023-10-31 Anshumitra Baul , Nicholas Walker , Juana Moreno , Ka-Ming Tam

Cryogenic electron tomography is a technique for imaging biological samples in 3D. A microscope collects a series of 2D projections of the sample, and the goal is to reconstruct the 3D density of the sample called the tomogram.…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Simon Wiedemann , Reinhard Heckel

Atomic-resolution imaging with scanning transmission electron microscopy is a powerful tool for characterizing the nanoscale structure of materials, in particular features such as defects, local strains, and symmetry-breaking distortions.…

Cryo-electron tomography (cryo-ET) provides direct 3D visualization of macromolecules inside the cell, enabling analysis of their in situ morphology. This morphology can be regarded as an SE(3)-invariant, denoised volumetric representation…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Mostofa Rafid Uddin , Mahek Vora , Qifeng Wu , Muyuan Chen , Min Xu

A new approach to the problem of topological freezing in gauge theories is introduced in which a physical volume preserving coarsening of the lattice induces sufficient energy variation in the Hamiltonian to overcome large topological…

High Energy Physics - Lattice · Physics 2023-12-20 Dean Howarth , Adam J Peterson

We study the problem of estimating a large, low-rank matrix corrupted by additive noise of unknown covariance, assuming one has access to additional side information in the form of noise-only measurements. We study the Whiten-Shrink-reColor…

Statistics Theory · Mathematics 2023-07-18 Matan Gavish , William Leeb , Elad Romanov

Tomography is an imaging technique that works by reconstructing a scene from acquired data in the form of line integrals of the imaging domain. A fundamental underlying assumption in the reconstruction procedure is the precise alignment of…

Numerical Analysis · Mathematics 2018-07-13 Toby Sanders

We report Tensorial Tomographic Differential Phase-Contrast microscopy (T2DPC), a quantitative label-free tomographic imaging method for simultaneous measurement of phase and anisotropy. T2DPC extends differential phase-contrast microscopy,…

We introduce ICE-TIDE, a method for cryogenic electron tomography (cryo-ET) that simultaneously aligns observations and reconstructs a high-resolution volume. The alignment of tilt series in cryo-ET is a major problem limiting the…

Image and Video Processing · Electrical Eng. & Systems 2024-12-16 Valentin Debarnot , Vinith Kishore , Ricardo D. Righetto , Ivan Dokmanić

For the purpose of phase space reconstruction from nonlinear time series, delay selection is one of the most vital criteria. This is normally done by using a general measure viz., mutual information (MI). However, in that case, the delay…

Chaotic Dynamics · Physics 2014-09-23 Sanjay Kumar Palit , Sayan Mukherjee , D. K. Bhattacharya
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