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After performing comparison of the performance of seven different machine learning models on detection depression tasks to show that the choice of features is essential, we compare our methods and results with the published work of other…

Machine Learning · Statistics 2020-06-12 Milena Čukić Radenković , David Pokrajac , Victoria Lopez

In recent years, there has been a notable increase in the use of supervised detection methods of major depressive disorder (MDD) based on electroencephalogram (EEG) signals. However, the process of labeling MDD remains challenging. As a…

Machine Learning · Computer Science 2025-12-17 Li-Xuan Zhao , Chen-Yang Xu , Wen-Qiang Li , Bo Wang , Rong-Xing Wei , Qing-Hao Menga

Depression has affected millions of people worldwide and has become one of the most common mental disorders. Early mental disorder detection can reduce costs for public health agencies and prevent other major comorbidities. Additionally,…

Computation and Language · Computer Science 2024-04-09 Giuliano Lorenzoni , Cristina Tavares , Nathalia Nascimento , Paulo Alencar , Donald Cowan

We currently observe a disconcerting phenomenon in machine learning studies in psychiatry: While we would expect larger samples to yield better results due to the availability of more data, larger machine learning studies consistently show…

Background: Dementia, particularly Alzheimer's Disease (AD), is a progressive neurodegenerative disorder marked by cognitive decline. Early detection, especially at the Mild Cognitive Impairment (MCI) stage, is essential for timely…

Signal Processing · Electrical Eng. & Systems 2025-10-16 Shivani Ranjan , Anant Jain , Robin Badal , Amit Kumar , Harshal Shende , Deepak Joshi , Pramod Yadav , Lalan Kumar

Previous studies have shown the correlation between sensor data collected from mobile phones and human depression states. Compared to the traditional self-assessment questionnaires, the passive data collected from mobile phones is easier to…

Clinical studies reveal disruptions in brain structural connectivity (SC) and functional connectivity (FC) in neuropsychiatric disorders such as schizophrenia (SZ). Traditional approaches might rely solely on SC due to limited functional…

Image and Video Processing · Electrical Eng. & Systems 2026-01-27 Badhan Mazumder , Ayush Kanyal , Lei Wu , Vince D. Calhoun , Dong Hye Ye

In this paper, we aimed at reviewing several different approaches present today in the search for more accurate diagnostic and treatment management in mental healthcare. Our focus is on mood disorders, and in particular on the major…

Neurons and Cognition · Quantitative Biology 2019-03-28 Milena Cukic Radenkovic

We describe a new method to automatically discriminate between patients with Alzheimer's disease (AD) or mild cognitive impairment (MCI) and elderly controls, based on multidimensional classification of hippocampal shape features. This…

Severe traumatic brain injury can lead to disorders of consciousness (DOC) characterized by deficit in conscious awareness and cognitive impairment including coma, vegetative state, minimally consciousness, and lock-in syndrome. Of crucial…

Neurons and Cognition · Quantitative Biology 2013-10-14 Verónica Mäki-Marttunen , Ibai Diez , Jesus M. Cortes , Dante R. Chialvo , Mirta Villarreal

Functional magnetic resonance imaging (fMRI) is widely used for studying and diagnosing brain disorders, with functional connectivity (FC) matrices providing powerful representations of large-scale neural interactions. However, existing…

Tissues and Organs · Quantitative Biology 2026-04-17 Qianyu Chen , Shujian Yu

Psychiatric research has been hampered by an explanatory gap between psychiatric symptoms and their neural underpinnings, which has resulted in poor treatment outcomes. This situation has prompted us to shift from symptom-based diagnosis to…

Major Depressive Disorder (MDD), affecting millions worldwide, exhibits complex pathophysiology manifested through disrupted brain network dynamics. Although graph neural networks that leverage neuroimaging data have shown promise in…

Machine Learning · Computer Science 2025-11-25 Weidao Chen , Yuxiao Yang , Yueming Wang

Failure to timely diagnose and effectively treat depression leads to over 280 million people suffering from this psychological disorder worldwide. The information cues of depression can be harvested from diverse heterogeneous resources,…

Computer Vision and Pattern Recognition · Computer Science 2022-08-19 Ping-Cheng Wei , Kunyu Peng , Alina Roitberg , Kailun Yang , Jiaming Zhang , Rainer Stiefelhagen

Speech based depression classification has gained immense popularity over the recent years. However, most of the classification studies have focused on binary classification to distinguish depressed subjects from non-depressed subjects. In…

Audio and Speech Processing · Electrical Eng. & Systems 2021-04-12 Nadee Seneviratne , Carol Espy-Wilson

Depression detection using vocal biomarkers is a highly researched area. Articulatory coordination features (ACFs) are developed based on the changes in neuromotor coordination due to psychomotor slowing, a key feature of Major Depressive…

Audio and Speech Processing · Electrical Eng. & Systems 2021-04-12 Nadee Seneviratne , Carol Espy-Wilson

Using Instagram data from 166 individuals, we applied machine learning tools to successfully identify markers of depression. Statistical features were computationally extracted from 43,950 participant Instagram photos, using color analysis,…

Social and Information Networks · Computer Science 2016-08-16 Andrew G. Reece , Christopher M. Danforth

Functional Connectivity (FC) matrices measure the regional interactions in the brain and have been widely used in neurological brain disease classification. However, a FC matrix is neither a natural image which contains shape and texture…

Medical Physics · Physics 2020-01-10 Xiaodan Xing , Qingfeng Li , Hao Wei , Minqing Zhang , Yiqiang Zhan , Xiang Sean Zhou , Zhong Xue , Feng Shi

Brain networks from functional MRI have advanced our understanding of cortical activity and its disruption in neurodegenerative disorders. Recent work has increasingly focused on dynamic (time-varying) brain networks that capture both…

Neurons and Cognition · Quantitative Biology 2026-04-14 Nicolas Rubido , Venia Batziou , Marwan Fuad , Vesna Vuksanovic

A wide variety of methods have been developed for identifying depression, but they focus primarily on measuring the degree to which individuals are suffering from depression currently. In this work we explore the possibility of predicting…

Machine Learning · Computer Science 2022-03-22 Guansong Pang , Ngoc Thien Anh Pham , Emma Baker , Rebecca Bentley , Anton van den Hengel