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Electrochemical Biosensors are uniquely positioned to offer real-time in vivo molecular sensing due to their robustness to both biofluids and contaminants found in biofluids, and their adaptability for the detection of different analytes by…

Biological Physics · Physics 2024-10-04 Philip S Lukeman

Branched molecules of deoxyribonucleic acid (DNA) can self-assemble into nanostructures through complementary cohesive strand base pairing. The production of DNA nanostructures is valuable in targeted drug delivery and biomolecular…

Combinatorics · Mathematics 2022-03-15 D. Chloe Griffin , Jessica Sorrells

DNA-mediated computing is a novel technology that seeks to capitalize on the enormous informational capacity of DNA and has tremendous computational ability to compete with the current silicon-mediated computing, due to massive parallelism…

Emerging Technologies · Computer Science 2017-09-01 Jian-Jun Shu , Qi-Wen Wang , Kian-Yan Yong

DNA origami nanostructures provide programmable control over nanoscale geometry but remain challenging to image due to their low atomic number. Here, we systematically evaluate imaging strategies for both stained and unstained DNA origami…

In recent years there have been a number of proposals to utilize the specificity of DNA based interactions for potential applications in nanoscience. One interesting direction is the self-assembly of micro- and nanoparticle clusters using…

Soft Condensed Matter · Physics 2009-11-13 Nicholas A. Licata , Alexei V. Tkachenko

DNA computing is an unconventional approach to computing that harnesses the parallelism and information storage capabilities of DNA molecules. It has emerged as a promising field with potential applications in solving a variety of…

Emerging Technologies · Computer Science 2024-06-04 Muhammad Asad Tariq , Rafay Junaid , Muhammad Mehdy Hasnain , Danyal Farhat

In the current world due to the huge demand for storage, DNA-based storage solution sounds quite promising because of their longevity, low power consumption, and high capacity. However in real life storing data in the form of DNA is quite…

Information Theory · Computer Science 2024-04-09 Sanket Doshi , Mihir Gohel , Manish K. Gupta

Membrane morphology and its dynamic adaptation regulate many cellular functions, which are often mediated by membrane proteins. Advances in DNA nanotechnology have enabled the realization of various protein-inspired structures and functions…

Patchy particles have received great attention due to their ability to develop directional and selective interactions and serve as building units for the self-assembly of innovative colloidal molecules and crystalline structures. Although…

Soft Condensed Matter · Physics 2023-01-16 Rawan Khalaf , Andrea Viamonte , Etienne Ducrot , Rémi Mérindol , Serge Ravaine

We study DNA self-assembly and DNA computation using a coarse-grained DNA model within the directional dynamic bonding framework {[}C. Svaneborg, Comp. Phys. Comm. 183, 1793 (2012){]}. In our model, a single nucleotide or domain is…

Soft Condensed Matter · Physics 2012-06-13 Carsten Svaneborg , Harold Fellermann , Steen Rasmussen

Molecular electronics and other technologies whose components comprise individual molecules have been pursued for half a century because the molecular scale represents the limit of miniaturisation of objects whose structure is tuneable for…

We show how coarse-grained modelling combined with umbrella sampling using distance-based order parameters can be applied to compute the free-energy landscapes associated with mechanical deformations of large DNA nanostructures. We…

Soft Condensed Matter · Physics 2022-02-21 Chak Kui Wong , Chuyan Tang , John S. Schreck , Jonathan P. K. Doye

In the past few years, Differentiable Neural Architecture Search (DNAS) rapidly imposed itself as the trending approach to automate the discovery of deep neural network architectures. This rise is mainly due to the popularity of DARTS, one…

Machine Learning · Computer Science 2023-05-02 Alexandre Heuillet , Ahmad Nasser , Hichem Arioui , Hedi Tabia

A powerful and flexible method of 3D nano-printing, based on focusing charged aerosol, has been developed. The self-consistent electric field configuration, created with a holey floating mask and used as the scaffold for printing…

Applied Physics · Physics 2018-12-14 Wooik Jung , Yoon-ho Jung , Peter V. Pikhitsa , Jooyeon Shin , Kijoon Bang , Jicheng Feng , Mansoo Choi

Three-dimensional (3D) printing has emerged as a powerful tool for material, food, and life science research and development, where the technology democratization necessitates the advancement of open-source platforms. Herein, we developed a…

Soft Condensed Matter · Physics 2022-03-16 Iek Man Lei , Yaqi Sheng , Chon Lok Lei , Cillian Leow , Yan Yan Shery Huang

The oxDNA model of DNA has been applied widely to systems in biology, biophysics and nanotechnology. It is currently available via two independent open source packages. Here we present a set of clearly-documented exemplar simulations that…

Biomolecules · Quantitative Biology 2022-09-26 Aditya Sengar , Thomas E. Ouldridge , Oliver Henrich , Lorenzo Rovigatti , Petr Sulc

The term Big Data is usually used to describe huge amount of data that is generated by humans from digital media such as cameras, internet, phones, sensors etc. By building advanced analytics on the top of big data, one can predict many…

Emerging Technologies · Computer Science 2014-05-19 Shalin Shah , Dixita Limbachiya , Manish K. Gupta

Synthetic molecular motors are an appealing means to control motion at the nanoscale, but understanding their behaviour as single-molecule actuators and integrating them into larger, functional systems remain technical challenges.…

DNA is an ideal candidate to organize matter on the nanoscale, primarily due to the specificity and complexity of DNA based interactions. Recent advances in this direction include the self-assembly of colloidal crystals using DNA grafted…

Soft Condensed Matter · Physics 2009-11-13 Nicholas A. Licata , Alexei V. Tkachenko

We developed NameMyGene, a web tool and a stand alone program to easily generate putative family-based names for small RNA sequences so that laboratories can easily organize, analyze, and observe patterns from, the massive amount of data…

Cryptography and Security · Computer Science 2012-10-25 Guodong Liu , Zhihua Li , Yuefeng Lin , Bino John