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Error backpropagation is a highly effective mechanism for learning high-quality hierarchical features in deep networks. Updating the features or weights in one layer, however, requires waiting for the propagation of error signals from…

Neural and Evolutionary Computing · Computer Science 2017-11-21 Hesham Mostafa , Vishwajith Ramesh , Gert Cauwenberghs

Speech enhancement has benefited from the success of deep learning in terms of intelligibility and perceptual quality. Conventional time-frequency (TF) domain methods focus on predicting TF-masks or speech spectrum, via a naive convolution…

Audio and Speech Processing · Electrical Eng. & Systems 2020-09-24 Yanxin Hu , Yun Liu , Shubo Lv , Mengtao Xing , Shimin Zhang , Yihui Fu , Jian Wu , Bihong Zhang , Lei Xie

Backpropagation (BP) is the standard algorithm for training the deep neural networks that power modern artificial intelligence including large language models. However, BP is energy inefficient and unlikely to be implemented by the brain.…

Machine Learning · Computer Science 2025-10-30 Francesco Innocenti

Attention-based deep networks have been successfully applied on textual data in the field of NLP. However, their application on protein sequences poses additional challenges due to the weak semantics of the protein words, unlike the plain…

Machine Learning · Computer Science 2022-08-29 Ashish Ranjan , Md Shah Fahad , Akshay Deepak

The inapplicability of amino acid covariation methods to small protein families has limited their use for structural annotation of whole genomes. Recently, deep learning has shown promise in allowing accurate residue-residue contact…

Biomolecules · Quantitative Biology 2019-09-10 Joe G Greener , Shaun M Kandathil , David T Jones

Purpose: This study aimed to enhance protein sequence classification using natural language processing (NLP) techniques while addressing the impact of sequence similarity on model performance. We compared various machine learning and deep…

Quantitative Methods · Quantitative Biology 2025-05-26 Huma Perveen , Julie Weeds

The intrinsic difficulty in adapting deep learning models to non-stationary environments limits the applicability of neural networks to real-world tasks. This issue is critical in practical supervised learning settings, such as the ones in…

Machine Learning · Computer Science 2023-06-09 Simone Marullo , Matteo Tiezzi , Marco Gori , Stefano Melacci , Tinne Tuytelaars

The ability of deep convolutional neural networks (CNN) to learn discriminative spectro-temporal patterns makes them well suited to environmental sound classification. However, the relative scarcity of labeled data has impeded the…

Sound · Computer Science 2017-04-05 Justin Salamon , Juan Pablo Bello

Convolutional Neural Networks experience catastrophic forgetting when optimized on a sequence of learning problems: as they meet the objective of the current training examples, their performance on previous tasks drops drastically. In this…

Computer Vision and Pattern Recognition · Computer Science 2020-04-02 Davide Abati , Jakub Tomczak , Tijmen Blankevoort , Simone Calderara , Rita Cucchiara , Babak Ehteshami Bejnordi

An important part of breast cancer staging is the assessment of the sentinel axillary node for early signs of tumor spreading. However, this assessment by pathologists is not always easy and retrospective surveys often requalify the status…

Quantitative Methods · Quantitative Biology 2024-04-30 Eric Bonnet

Deep learning neural networks have emerged as one of the most powerful classification tools for vision related applications. However, the computational and energy requirements associated with such deep nets can be quite high, and hence…

Computer Vision and Pattern Recognition · Computer Science 2016-01-29 Priyadarshini Panda , Abhronil Sengupta , Kaushik Roy

The customizable nature of deep learning models have allowed them to be successful predictors in various disciplines. These models are often trained with respect to thousands or millions of instances for complicated problems, but the…

Machine Learning · Computer Science 2019-12-24 Drimik Roy Chowdhury , Muhammad Firmansyah Kasim

Recurrent neural networks are used to forecast time series in finance, climate, language, and from many other domains. Reservoir computers are a particularly easily trainable form of recurrent neural network. Recently, a "next-generation"…

Machine Learning · Computer Science 2023-03-28 Sarah E. Marzen , Paul M. Riechers , James P. Crutchfield

A sequential training method for large-scale feedforward neural networks is presented. Each layer of the neural network is decoupled and trained separately. After the training is completed for each layer, they are combined together. The…

Machine Learning · Computer Science 2019-05-21 Jongrae Kim

Recent studies in image classification have demonstrated a variety of techniques for improving the performance of Convolutional Neural Networks (CNNs). However, attempts to combine existing techniques to create a practical model are still…

Computer Vision and Pattern Recognition · Computer Science 2020-03-16 Jungkyu Lee , Taeryun Won , Tae Kwan Lee , Hyemin Lee , Geonmo Gu , Kiho Hong

Protein structure-based property prediction has emerged as a promising approach for various biological tasks, such as protein function prediction and sub-cellular location estimation. The existing methods highly rely on experimental protein…

Machine Learning · Computer Science 2023-10-20 Yufei Huang , Siyuan Li , Jin Su , Lirong Wu , Odin Zhang , Haitao Lin , Jingqi Qi , Zihan Liu , Zhangyang Gao , Yuyang Liu , Jiangbin Zheng , Stan. ZQ. Li

Proteins perform essential biological functions, and accurate classification of their sequences is critical for understanding structure-function relationships, enzyme mechanisms, and molecular interactions. This study presents a deep…

Quantitative Methods · Quantitative Biology 2025-11-19 Pratik Chakraborty , Aryan Bhargava

The research presented in this paper advances the integration of Hebbian learning into Convolutional Neural Networks (CNNs) for image processing, systematically exploring different architectures to build an optimal configuration, adhering…

Neural and Evolutionary Computing · Computer Science 2026-05-05 Julian Jimenez Nimmo , Esther Mondragon

Continual learning is an emerging topic in the field of deep learning, where a model is expected to learn continuously for new upcoming tasks without forgetting previous experiences. This field has witnessed numerous advancements, but few…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Aupendu Kar , Krishnendu Ghosh , Prabir Kumar Biswas

Deep Convolutional Neural Network (CNN) is a special type of Neural Networks, which has shown exemplary performance on several competitions related to Computer Vision and Image Processing. Some of the exciting application areas of CNN…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Asifullah Khan , Anabia Sohail , Umme Zahoora , Aqsa Saeed Qureshi
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