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In this paper, we present an adaptation of the sequence-to-sequence model for structured output prediction in vision tasks. In this model the output variables for a given input are predicted sequentially using neural networks. The…

Computer Vision and Pattern Recognition · Computer Science 2016-10-25 Georgia Gkioxari , Alexander Toshev , Navdeep Jaitly

Convolutional neural networks (CNNs) have constantly achieved better performance over years by introducing more complex topology, and enlarging the capacity towards deeper and wider CNNs. This makes the manual design of CNNs extremely…

Computer Vision and Pattern Recognition · Computer Science 2022-12-09 Bin Wang , Bing Xue , Mengjie Zhang

Many complex problems, such as natural language processing or visual object detection, are solved using deep learning. However, efficient training of complex deep convolutional neural networks for large data sets is computationally…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-06-06 Andre Viebke , Sabri Pllana , Suejb Memeti , Joanna Kolodziej

In this paper we experiment with using neural network structures to predict a protein's secondary structure ({\alpha} helix positions) from only its primary structure (amino acid sequence). We implement a fully connected neural network…

Machine Learning · Computer Science 2022-08-25 Sidharth Malhotra , Robin Walters

Computational protein design has a wide variety of applications. Despite its remarkable success, designing a protein for a given structure and function is still a challenging task. On the other hand, the number of solved protein structures…

Quantitative Methods · Quantitative Biology 2018-04-26 Jingxue Wang , Huali Cao , John Z. H. Zhang , Yifei Qi

A cascading system of hierarchical, artificial neural networks (named PRED-CLASS) is presented for the generalized classification of proteins into four distinct classes-transmembrane, fibrous, globular, and mixed-from information solely…

Quantitative Methods · Quantitative Biology 2009-02-19 Claude Pasquier , Vasilis Promponas , Stavros Hamodrakas

Deep Learning has a hierarchical network architecture to represent the complicated feature of input patterns. The adaptive structural learning method of Deep Belief Network (DBN) has been developed. The method can discover an optimal number…

Neural and Evolutionary Computing · Computer Science 2018-08-28 Shin Kamada , Takumi Ichimura , Toshihide Harada

Directed evolution is an iterative laboratory process of designing proteins with improved function by iteratively synthesizing new protein variants and evaluating their desired property with expensive and time-consuming biochemical…

Machine Learning · Computer Science 2025-09-08 Matouš Soldát , Jiří Kléma

Scene parsing is an important and challenging prob- lem in computer vision. It requires labeling each pixel in an image with the category it belongs to. Tradition- ally, it has been approached with hand-engineered features from color…

Machine Learning · Statistics 2014-11-18 Rahul Mohan

Convolutional Neural Networks (CNNs) have achieved remarkable success across a wide range of machine learning tasks by leveraging hierarchical feature learning through deep architectures. However, the large number of layers and millions of…

Machine Learning · Statistics 2025-11-18 Biyi Fang , Truong Vo , Jean Utke , Diego Klabjan

Deep convolutional neural networks (DCNN) have enjoyed great successes in many signal processing applications because they can learn complex, non-linear causal relationships from input to output. In this light, DCNNs are well suited for the…

Image and Video Processing · Electrical Eng. & Systems 2018-10-31 Xi Zhang , Xiaolin Wu

In recent years, there has been a surge in the development of 3D structure-based pre-trained protein models, representing a significant advancement over pre-trained protein language models in various downstream tasks. However, most existing…

Machine Learning · Computer Science 2024-06-04 Jiale Zhao , Wanru Zhuang , Jia Song , Yaqi Li , Shuqi Lu

Deep Convolutional Neural Networks (CNNs) have significantly advanced deep learning, driving breakthroughs in computer vision, natural language processing, medical diagnosis, object detection, and speech recognition. Architectural…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Saddam Hussain Khan , Rashid Iqbal

As proteins with similar structures often have similar functions, analysis of protein structures can help predict protein functions and is thus important. We consider the problem of protein structure classification, which computationally…

Machine Learning · Statistics 2019-10-08 Hongyu Guo , Khalique Newaz , Scott Emrich , Tijana Milenkovic , Jun Li

Accurately modeling the protein fitness landscapes holds great importance for protein engineering. Recently, due to their capacity and representation ability, pre-trained protein language models have achieved state-of-the-art performance in…

Biomolecules · Quantitative Biology 2024-02-06 Ziyi Zhou , Liang Zhang , Yuanxi Yu , Mingchen Li , Liang Hong , Pan Tan

Understanding the relationships between protein sequence, structure and function is a long-standing biological challenge with manifold implications from drug design to our understanding of evolution. Recently, protein language models have…

Quantitative Methods · Quantitative Biology 2024-01-29 Dexiong Chen , Philip Hartout , Paolo Pellizzoni , Carlos Oliver , Karsten Borgwardt

In this study, we propose a novel deep learning-based method to predict an optimized structure for a given boundary condition and optimization setting without using any iterative scheme. For this purpose, first, using open-source topology…

Machine Learning · Computer Science 2018-10-30 Yonggyun Yu , Taeil Hur , Jaeho Jung , In Gwun Jang

Semantic Segmentation using deep convolutional neural network pose more complex challenge for any GPU intensive task. As it has to compute million of parameters, it results to huge memory consumption. Moreover, extracting finer features and…

Computer Vision and Pattern Recognition · Computer Science 2020-05-19 Sharif Amit Kamran , Ali Shihab Sabbir

Continual Learning (CL) enables machine learning models to learn from continuously shifting new training data in absence of data from old tasks. Recently, pretrained vision transformers combined with prompt tuning have shown promise for…

Computer Vision and Pattern Recognition · Computer Science 2024-04-01 Anurag Roy , Riddhiman Moulick , Vinay K. Verma , Saptarshi Ghosh , Abir Das

In recent years, deep learning techniques have outperformed traditional models in many machine learning tasks. Deep neural networks have successfully been applied to address time series forecasting problems, which is a very important topic…

Machine Learning · Computer Science 2021-04-09 Pedro Lara-Benítez , Manuel Carranza-García , José C. Riquelme