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The Segment Anything Model (SAM), originally built on a 2D Vision Transformer (ViT), excels at capturing global patterns in 2D natural images but struggles with 3D medical imaging modalities like CT and MRI. These modalities require…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Xiang Gao , Kai Lu

Accurate medical image segmentation requires both long-range contextual reasoning and precise boundary delineation, a task where existing transformer- and diffusion-based paradigms are frequently bottlenecked by quadratic computational…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Ahmed Marouane Djouama , Abir Belaala , Abdellah Zakaria Sellam , Salah Eddine Bekhouche , Cosimo Distante , Abdenour Hadid

For the example of the SiC(111)-(3x3) reconstruction we show that a holographic interpretation of discrete Low Energy Electron Diffraction (LEED) spot intensities arising from ordered, large unit cell superstructures can give direct access…

Materials Science · Physics 2009-10-31 K. Reuter , J. Schardt , J. Bernhardt , H. Wedler , U. Starke , K. Heinz

We demonstrate high-resolution non-iterative holographic coherent diffraction imaging with hard X-rays using a novel phase-shifting reference, fabricated by atomic layer deposition to produce nanosharp 3D structure. The method surpasses the…

Mesoscale and Nanoscale Physics · Physics 2016-10-17 Mirna Saliba , Jeroen Bosgra , Christoph Rau , Christian David , Aaron D. Parsons , Ulrich H. Wagner , Pierre Thibault

In optical diffraction tomography (ODT), a sample's 3D refractive-index (RI) is often reconstructed after illuminating it from multiple angles, with the assumption that the sample remains static throughout data collection. When the sample…

Optics · Physics 2024-12-13 Jeongsoo Kim , Shwetadwip Chowdhury

Structured illumination microscopy (SIM) has emerged as an essential technique for 3D and live-cell super-resolution imaging. However, to date, there has not been a dedicated workshop or journal issue covering the various aspects of SIM,…

Recently it was reported that deeply subwavelength features of free space superoscillatory electromagnetic fields can be observed experimentally and used in optical metrology with nanoscale resolution [Science 364, 771 (2019)]. Here we…

Optics · Physics 2019-10-08 T. Pu , V. Savinov , G. Yuan , N. Papasimakis , N. I. Zheludev

Optical diffraction tomography (ODT) is a three-dimensional (3D) label-free imaging technique. The 3D refractive index distribution of a sample can be reconstructed from multiple two-dimensional optical field images via ODT. Herein, we…

Optics · Physics 2021-02-03 Chansuk Park , Kyeoreh Lee , Yoonseok Baek , Yongkeun Park

High angular resolution diffusion imaging (HARDI) demands a lager amount of data measurements compared to diffusion tensor imaging, restricting its use in practice. In this work, we explore a learning-based approach to reconstruct HARDI…

Computer Vision and Pattern Recognition · Computer Science 2019-03-25 Shi Yin , Zhengqiang Zhang , Qinmu Peng , Xinge You

Coherent diffractive imaging (CDI) has been widely applied in the physical and biological sciences using synchrotron radiation, XFELs, high harmonic generation, electrons and optical lasers. One of CDI's important applications is to probe…

Instrumentation and Detectors · Physics 2018-07-04 Yuan Hung Lo , Lingrong Zhao , Marcus Gallagher-Jones , Arjun Rana , Jared Lodico , Weikun Xiao , B. C. Regan , Jianwei Miao

We demonstrate numerical refocusing in coherent confocal laser scanning microscopy based on synthetic optical holography. This physics-based approach implements a computational propagation on the complex signal recovered in synthetic…

Inverse rendering aims to reconstruct geometry and reflectance of objects from images. Despite recent progress, existing methods often produces inaccurate reconstructions that are sensitive to ambient illumination conditions. Here we…

Computer Vision and Pattern Recognition · Computer Science 2026-05-29 Hoon-Gyu Chung , Jinnyeong Kim , Hyunwoo Kang , Seung-Hwan Baek

A lateral shear interferometer based digital holographic microscopy has been realized to study the morphology dynamics of Human red blood cells quantitatively. Here, a lateral shear interferometer is embedded with a conventional microscope…

Image and Video Processing · Electrical Eng. & Systems 2019-09-10 Shital Devinder , Ashish Lal , Tathagato Rai Dastidar , Satish Kumar Dubey

An inverse source reconstruction (ISR) based 3-D near-field (NF) passive radar microwave imaging method utilizing modulated signals is presented. The modulated signals from a non-cooperative transmitter are scattered by the targets of…

Image and Video Processing · Electrical Eng. & Systems 2026-05-06 Quanfeng Wang , Alexander H. Paulus , Thomas F. Eibert

In this chapter, we introduce digital holographic microscopy (DHM) as a marker-free method to determine the refractive index of single, spherical cells in suspension. The refractive index is a conclusive measure in a biological context.…

Quantitative Methods · Quantitative Biology 2018-04-06 Mirjam Schürmann , Jana Scholze , Paul Müller , Chii J. Chan , Andrew E. Ekpenyong , Kevin J. Chalut , Jochen Guck

CDI is a lensless imaging technique that enables atomic-resolution imaging of non-crystalline specimens and their dynamics. However, its broader implementation has been hindered by the instability and ill-posedness of its reconstruction…

Optics · Physics 2025-12-11 Zhe Hu , Zisheng Yao , Yuhe Zhang , Pablo Villanueva-Perez

We introduce a compact, two-camera laparoscope that combines active stereo depth estimation and speckle-illumination spatial frequency domain imaging (si-SFDI) to map profile-corrected, pixel-level absorption and reduced scattering optical…

Optics · Physics 2025-01-27 Anthony A. Song , Mason T. Chen , Taylor L. Bobrow , Nicholas J. Durr

Optical coherence tomography (OCT) is a non-invasive, micrometer-scale imaging modality that has become a clinical standard in ophthalmology. By raster-scanning the retina, sequential cross-sectional image slices are acquired to generate…

Image and Video Processing · Electrical Eng. & Systems 2024-02-20 Stefan Ploner , Jungeun Won , Julia Schottenhamml , Jessica Girgis , Kenneth Lam , Nadia Waheed , James Fujimoto , Andreas Maier

In optical diffraction tomography (ODT), the three-dimensional scattering potential of a microscopic object rotating around its center is recovered by a series of illuminations with coherent light. Reconstruction algorithms such as the…

Numerical Analysis · Mathematics 2022-09-02 Robert Beinert , Michael Quellmalz

Single particle imaging (SPI) at X-ray free electron lasers (XFELs) is particularly well suited to determine the 3D structure of particles in their native environment. For a successful reconstruction, diffraction patterns originating from a…

Data Analysis, Statistics and Probability · Physics 2021-12-17 Dameli Assalauova , Alexandr Ignatenko , Fabian Isensee , Sergey Bobkov , Darya Trofimova , Ivan A. Vartanyants
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