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MRI images of the same subject in different contrasts contain shared information, such as the anatomical structure. Utilizing the redundant information amongst the contrasts to sub-sample and faithfully reconstruct multi-contrast images…

Computer Vision and Pattern Recognition · Computer Science 2021-04-01 Xinwen Liu , Jing Wang , Fangfang Tang , Shekhar S. Chandra , Feng Liu , Stuart Crozier

Small animal PET scanners require high spatial resolution and good sensitivity. To reconstruct high-resolution images in 3D-PET, iterative methods, such as OSEM, are superior to analytical reconstruction algorithms, although their high…

Medical Physics · Physics 2007-05-23 J. L. Herraiz , S. Espana , J. J. Vaquero , M. Desco , J. M. Udias

Proteins, essential to biological systems, perform functions intricately linked to their three-dimensional structures. Understanding the relationship between protein structures and their amino acid sequences remains a core challenge in…

Quantitative Methods · Quantitative Biology 2024-11-04 Liang He , Peiran Jin , Yaosen Min , Shufang Xie , Lijun Wu , Tao Qin , Xiaozhuan Liang , Kaiyuan Gao , Yuliang Jiang , Tie-Yan Liu

Current large scale implementations of deep learning and data mining require thousands of processors, massive amounts of off-chip memory, and consume gigajoules of energy. Emerging memory technologies such as nanoscale two-terminal…

Neural and Evolutionary Computing · Computer Science 2016-11-15 S. Burc Eryilmaz , Emre Neftci , Siddharth Joshi , SangBum Kim , Matthew BrightSky , Hsiang-Lan Lung , Chung Lam , Gert Cauwenberghs , H. -S. Philip Wong

Motivation: Protein-ligand affinity prediction is an important part of structure-based drug design. It includes molecular docking and affinity prediction. Although molecular dynamics can predict affinity with high accuracy at present, it is…

Biomolecules · Quantitative Biology 2021-05-12 Yeji Wang , Shuo Wu , Yanwen Duan , Yong Huang

This paper presents a low-power cache architecture based on the series interconnection of conventional 6-transistor static random-access memory (6T SRAM) cells. The proposed approach aims to reduce leakage power in SRAM-based cache memories…

Hardware Architecture · Computer Science 2026-04-23 Naser Khatti Dizabadi , Ceyda Elcin Kaya

We propose a new class of efficient decoding algorithms for Reed-Muller (RM) codes over binary-input memoryless channels. The algorithms are based on projecting the code on its cosets, recursively decoding the projected codes (which are…

Information Theory · Computer Science 2020-02-27 Min Ye , Emmanuel Abbe

In real industrial processes, fault diagnosis methods are required to learn from limited fault samples since the procedures are mainly under normal conditions and the faults rarely occur. Although attention mechanisms have become popular in…

Machine Learning · Computer Science 2023-09-26 Mengxuan Li , Peng Peng , Jingxin Zhang , Hongwei Wang , Weiming Shen

Proteins perform their functions usually by interacting with other proteins. Predicting which proteins interact is a fundamental problem. Experimental methods are slow, expensive, and have a high rate of error. Many computational methods…

Biomolecules · Quantitative Biology 2017-05-22 Yiwei Li , Lucian Ilie

The accuracy of finger vein recognition systems gets degraded due to low and uneven contrast between veins and surroundings, often resulting in poor detection of vein patterns. We propose a finger-vein enhancement technique, ResFPN…

Image and Video Processing · Electrical Eng. & Systems 2023-07-03 Ketan Kotwal , Sebastien Marcel

This paper introduces a high-throughput software tool framework called {\it sam2bam} that enables users to significantly speedup pre-processing for next-generation sequencing data. The sam2bam is especially efficient on single-node…

Genomics · Quantitative Biology 2017-02-08 Takeshi Ogasawara , Yinhe Cheng , Tzy-Hwa Kathy Tzeng

Matching pedestrians across multiple camera views known as human re-identification (re-identification) is a challenging problem in visual surveillance. In the existing works concentrating on feature extraction, representations are formed…

Computer Vision and Pattern Recognition · Computer Science 2016-07-29 Rahul Rama Varior , Bing Shuai , Jiwen Lu , Dong Xu , Gang Wang

Many computerized methods for RNA-RNA interaction structure prediction have been developed. Recently, $O(N^6)$ time and $O(N^4)$ space dynamic programming algorithms have become available that compute the partition function of RNA-RNA…

Mathematical Physics · Physics 2010-07-15 Andrew X. Li , Manja Marz , Jing Qin , Christian M. Reidys

DNA sequence alignment involves assigning short DNA reads to the most probable locations on an extensive reference genome. This process is crucial for various genomic analyses, including variant calling, transcriptomics, and epigenomics.…

The Shortest Common Superstring (SCS) problem is a fundamental task in sequence analysis. In genome assembly, however, the double-stranded nature of DNA implies that each fragment may occur either in its original orientation or as its…

Data Structures and Algorithms · Computer Science 2026-03-30 Ryosuke Yamano , Tetsuo Shibuya

Neuromorphic architectures mimicking biological neural networks have been proposed as a much more efficient alternative to conventional von Neumann architectures for the exploding compute demands of AI workloads. Recent neuroscience theory…

Hardware Architecture · Computer Science 2024-05-21 Harideep Nair , William Leyman , Agastya Sampath , Quinn Jacobson , John Paul Shen

Sequences of nucleotides (for DNA and RNA) or amino acids (for proteins) are central objects in biology. Among the most important computational problems is that of sequence alignment, i.e. arranging sequences from different organisms in…

Quantitative Methods · Quantitative Biology 2020-12-08 Anna Paola Muntoni , Andrea Pagnani , Martin Weigt , Francesco Zamponi

Structured illumination microscopy (SIM) is a very important super-resolution microscopy technique, which provides high speed super-resolution with about two-fold spatial resolution enhancement. Several attempts aimed at improving the…

Computer Vision and Pattern Recognition · Computer Science 2016-02-23 Amit Lal , Chunyan Shan , Peng Xi

We present a framework for the design of optimal assembly algorithms for shotgun sequencing under the criterion of complete reconstruction. We derive a lower bound on the read length and the coverage depth required for reconstruction in…

Genomics · Quantitative Biology 2013-02-20 Guy Bresler , Ma'ayan Bresler , David Tse

The stretch processing architecture is commonly used for frequency modulated continuous wave (FMCW) radar due to its inexpensive hardware, low sampling rate, and simple architecture. However, the stretch processing architecture is not able…

Signal Processing · Electrical Eng. & Systems 2021-11-02 Moein Movafagh , Avik Santra , Daniel Oloumi