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Predicting an individual's aging trajectory is a central challenge in preventative medicine and bioinformatics. While machine learning models can predict chronological age from biomarkers, they often fail to capture the dynamic,…

Machine Learning · Computer Science 2025-08-14 Nazira Dunbayeva , Yulong Li , Yutong Xie , Imran Razzak

Automated diagnosis of Alzheimer Disease(AD) from brain imaging, such as magnetic resonance imaging (MRI), has become increasingly important and has attracted the community to contribute many deep learning methods. However, many of these…

Image and Video Processing · Electrical Eng. & Systems 2024-03-01 Yifeng Wang , Ke Chen , Haohan Wang

Generalizability of deep learning models may be severely affected by the difference in the distributions of the train (source domain) and the test (target domain) sets, e.g., when the sets are produced by different hardware. As a…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Ivan Zakazov , Vladimir Shaposhnikov , Iaroslav Bespalov , Dmitry V. Dylov

Epigenetic observations are represented by the total number of reads from a given pool of cells and the number of methylated reads, making it reasonable to model this data by a binomial distribution. There are numerous factors that can…

Applications · Statistics 2020-04-29 Aliaksandr Hubin , Geir O Storvik , Paul E Grini , Melinka A Butenko

Deep learning models perform best when tested on target (test) data domains whose distribution is similar to the set of source (train) domains. However, model generalization can be hindered when there is significant difference in the…

Computer Vision and Pattern Recognition · Computer Science 2020-08-19 Pulkit Khandelwal , Paul Yushkevich

Data-driven fault diagnosis methods often require abundant labeled examples for each fault type. On the contrary, real-world data is often unlabeled and consists of mostly healthy observations and only few samples of faulty conditions. The…

Signal Processing · Electrical Eng. & Systems 2021-11-19 Qin Wang , Cees Taal , Olga Fink

The objective of this study is to predict suicidal and non-suicidal deaths from DNA methylation data using a modern machine learning algorithm. We used support vector machines to classify existing secondary data consisting of normalized…

Genomics · Quantitative Biology 2020-04-07 Rifat Zahan , Ian McQuillan , Nathaniel D. Osgood

Genomic phenotypes, such as DNA methylation and chromatin accessibility, can be used to characterize the transcriptional and regulatory activity of DNA within a cell. Recent technological advances have made it possible to measure such…

Methodology · Statistics 2016-11-15 Jean Morrison , Noah Simon , Daniela Witten

As the aging population grows, particularly for the baby boomer generation, the United States is witnessing a significant increase in the elderly population experiencing multifunctional disabilities. These disabilities, stemming from a…

Machine Learning · Computer Science 2024-04-09 Suiyao Chen , Xinyi Liu , Yulei Li , Jing Wu , Handong Yao

Gaze is the essential manifestation of human attention. In recent years, a series of work has achieved high accuracy in gaze estimation. However, the inter-personal difference limits the reduction of the subject-independent gaze estimation…

Computer Vision and Pattern Recognition · Computer Science 2020-11-17 Zidong Guo , Zejian Yuan , Chong Zhang , Wanchao Chi , Yonggen Ling , Shenghao Zhang

We develop Bayesian inference methods for a recently-emerging type of epigenetic data to study the transmission fidelity of DNA methylation patterns over cell divisions. The data consist of parent-daughter double-stranded DNA methylation…

Bone age assessment is a task performed daily in hospitals worldwide. This involves a clinician estimating the age of a patient from a radiograph of the non-dominant hand. Our approach to automated bone age assessment is to modularise the…

Machine Learning · Computer Science 2014-06-19 Anthony Bagnall , Luke Davis

Electroencephalography (EEG) signals reflect activities on certain brain areas. Effective classification of time-varying EEG signals is still challenging. First, EEG signal processing and feature engineering are time-consuming and highly…

Human-Computer Interaction · Computer Science 2019-08-27 Xiang Zhang , Lina Yao , Xianzhi Wang , Wenjie Zhang , Shuai Zhang , Yunhao Liu

DNA methylation is a well-studied genetic modification crucial to regulate the functioning of the genome. Its alterations play an important role in tumorigenesis and tumor-suppression. Thus, studying DNA methylation data may help biomarker…

Genomics · Quantitative Biology 2018-04-16 Fabrizio Celli , Fabio Cumbo , Emanuel Weitschek

Supervised learning is well-known to fail at generalization under distribution shifts. In typical clinical settings, the source data is inaccessible and the target distribution is represented with a handful of samples: adaptation can only…

Computer Vision and Pattern Recognition · Computer Science 2022-05-18 Mathilde Bateson , Hervé Lombaert , Ismail Ben Ayed

Accurate Remaining Useful Life (RUL) prediction without labeled target domain data is a critical challenge, and domain adaptation (DA) has been widely adopted to address it by transferring knowledge from a labeled source domain to an…

Machine Learning · Computer Science 2026-03-18 Yubo Hou , Mohamed Ragab , Yucheng Wang , Min Wu , Abdulla Alseiari , Chee-Keong Kwoh , Xiaoli Li , Zhenghua Chen

The major challenge in today's computer vision scenario is the availability of good quality labeled data. In a field of study like image classification, where data is of utmost importance, we need to find more reliable methods which can…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Aashish Dhawan , Divyanshu Mudgal

Machine learning is driven by data, yet while their availability is constantly increasing, training data require laborious, time consuming and error-prone labelling or ground truth acquisition, which in some cases is very difficult or even…

Computer Vision and Pattern Recognition · Computer Science 2019-09-25 Vasileios Gkitsas , Antonis Karakottas , Nikolaos Zioulis , Dimitrios Zarpalas , Petros Daras

We introduce a new representation learning approach for domain adaptation, in which data at training and test time come from similar but different distributions. Our approach is directly inspired by the theory on domain adaptation…

Over the last years, dictionary learning method has been extensively applied to deal with various computer vision recognition applications, and produced state-of-the-art results. However, when the data instances of a target domain have a…

Computer Vision and Pattern Recognition · Computer Science 2015-06-04 Zhun Zhong , Zongmin Li , Runlin Li , Xiaoxia Sun
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