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Adaptive enrichment allows for pre-defined patient subgroups of interest to be investigated throughout the course of a clinical trial. Many trials which measure a long-term time-to-event endpoint often also routinely collect repeated…

Methodology · Statistics 2024-02-26 Abigail J. Burdon , Richard D. Baird , Thomas Jaki

Background: The increasing availability of databases containing both magnetic resonance imaging (MRI) and genetic data allows researchers to utilize multimodal data to better understand the characteristics of dementia of Alzheimer's type…

A typical domain adaptation approach is to adapt models trained on the annotated data in a source domain (e.g., sunny weather) for achieving high performance on the test data in a target domain (e.g., rainy weather). Whether the target…

Computer Vision and Pattern Recognition · Computer Science 2020-03-31 Ziwei Liu , Zhongqi Miao , Xingang Pan , Xiaohang Zhan , Dahua Lin , Stella X. Yu , Boqing Gong

In domain adaptation (DA), the effectiveness of deep learning-based models is often constrained by batch learning strategies that fail to fully apprehend the global statistical and geometric characteristics of data distributions. Addressing…

Machine Learning · Computer Science 2025-02-11 Lingkun Luo , Shiqiang Hu , Liming Chen

Materials property prediction models are usually evaluated using random splitting of datasets into training and test datasets, which not only leads to over-estimated performance due to inherent redundancy, typically existent in material…

Materials Science · Physics 2024-05-28 Jeffrey Hu , David Liu , Nihang Fu , Rongzhi Dong

Recent advances in domain adaptation, especially those applied to heterogeneous facial recognition, typically rely upon restrictive Euclidean loss functions (e.g., $L_2$ norm) which perform best when images from two different domains (e.g.,…

Computer Vision and Pattern Recognition · Computer Science 2020-08-20 Cedric Nimpa Fondje , Shuowen Hu , Nathaniel J. Short , Benjamin S. Riggan

Emerging diseases present challenges in symptom recognition and timely clinical intervention due to limited available information. An effective prognostic model could assist physicians in making accurate diagnoses and designing personalized…

Machine Learning · Computer Science 2025-02-12 Zhongji Zhang , Yuhang Wang , Yinghao Zhu , Xinyu Ma , Yasha Wang , Junyi Gao , Liantao Ma , Wen Tang , Xiaoyun Zhang , Ling Wang

Cross-modal MRI segmentation is of great value for computer-aided medical diagnosis, enabling flexible data acquisition and model generalization. However, most existing methods have difficulty in handling local variations in domain shift…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Bingnan Li , Zhitong Gao , Xuming He

Visual Domain Adaptation is a problem of immense importance in computer vision. Previous approaches showcase the inability of even deep neural networks to learn informative representations across domain shift. This problem is more severe…

Computer Vision and Pattern Recognition · Computer Science 2018-04-03 Swami Sankaranarayanan , Yogesh Balaji , Arpit Jain , Ser Nam Lim , Rama Chellappa

There has been a tremendous progress in Domain Adaptation (DA) for visual recognition tasks. Particularly, open-set DA has gained considerable attention wherein the target domain contains additional unseen categories. Existing open-set DA…

Computer Vision and Pattern Recognition · Computer Science 2020-04-10 Jogendra Nath Kundu , Naveen Venkat , Ambareesh Revanur , Rahul M , R. Venkatesh Babu

The ability to accurately recognize an individual's face with respect to human aging factor holds significant importance for various private as well as government sectors such as customs and public security bureaus, passport office, and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Wang Yao , Muhammad Ali Farooq , Joseph Lemley , Peter Corcoran

Predicting the efficacy of a drug for a given individual, using high-dimensional genomic measurements, is at the core of precision medicine. However, identifying features on which to base the predictions remains a challenge, especially when…

This study proposes a Transformer-based longitudinal modeling method to address challenges in clinical risk classification with heterogeneous Electronic Health Record (EHR) data, including irregular temporal patterns, large modality…

Machine Learning · Computer Science 2025-11-07 Anzhuo Xie , Wei-Chen Chang

Computer vision has flourished in recent years thanks to Deep Learning advancements, fast and scalable hardware solutions and large availability of structured image data. Convolutional Neural Networks trained on supervised tasks with…

Computer Vision and Pattern Recognition · Computer Science 2021-08-23 Antono D'Innocente

Semantic segmentation is a critical step in automated image interpretation and analysis where pixels are classified into one or more predefined semantically meaningful classes. Deep learning approaches for semantic segmentation rely on…

Computer Vision and Pattern Recognition · Computer Science 2023-07-10 Tushar Kataria , Beatrice Knudsen , Shireen Elhabian

Background: The analysis of DNA methylation is a key component in the development of personalized treatment approaches. A common way to measure DNA methylation is the calculation of beta values, which are bounded variables of the form M =…

Methodology · Statistics 2016-07-26 Leonie Weinhold , Simone Wahl , Matthias Schmid

The significant role of epigenetic mechanisms within natural systems has become increasingly clear. This paper uses a recently presented abstract, tunable Boolean genetic regulatory network model to explore aspects of epigenetics. It is…

Neural and Evolutionary Computing · Computer Science 2013-06-21 Larry Bull

Classical machine learning assumes that the training and test sets come from the same distributions. Therefore, a model learned from the labeled training data is expected to perform well on the test data. However, This assumption may not…

Machine Learning · Computer Science 2020-10-12 Abolfazl Farahani , Sahar Voghoei , Khaled Rasheed , Hamid R. Arabnia

Flexible laryngoscopy is commonly performed by otolaryngologists to detect laryngeal diseases and to recognize potentially malignant lesions. Recently, researchers have introduced machine learning techniques to facilitate automated…

Computer Vision and Pattern Recognition · Computer Science 2023-05-29 Tianxiao Zhang , Andrés M. Bur , Shannon Kraft , Hannah Kavookjian , Bryan Renslo , Xiangyu Chen , Bo Luo , Guanghui Wang

The brain age is a key indicator of brain health. While electroencephalography (EEG) is a practical tool for this task, existing models struggle with the common challenge of imperfect medical data, such as learning a ``normal'' baseline…

Machine Learning · Computer Science 2025-11-25 Kunyu Zhang , Mingxuan Wang , Xiangjie Shi , Haoxing Xu , Chao Zhang
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