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Dementia of Alzheimer's Type (DAT) is a complex disorder influenced by numerous factors, but it is unclear how each factor contributes to disease progression. An in-depth examination of these factors may yield an accurate estimate of…

Neural networks are known to be data hungry and domain sensitive, but it is nearly impossible to obtain large quantities of labeled data for every domain we are interested in. This necessitates the use of domain adaptation strategies. One…

Computation and Language · Computer Science 2019-10-08 Zi-Yi Dou , Xinyi Wang , Junjie Hu , Graham Neubig

The high dimensional nature of genomics data complicates feature selection, in particular in low sample size studies - not uncommon in clinical prediction settings. It is widely recognized that complementary data on the features, `co-data',…

Methodology · Statistics 2024-05-09 Mark A. van de Wiel , Wessel N. van Wieringen

Brain disorders are a major challenge to global health, causing millions of deaths each year. Accurate diagnosis of these diseases relies heavily on advanced medical imaging techniques such as Magnetic Resonance Imaging (MRI) and Computed…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Xuran Zhu

The performance of a machine learning model degrades when it is applied to data from a similar but different domain than the data it has initially been trained on. To mitigate this domain shift problem, domain adaptation (DA) techniques…

Machine Learning · Computer Science 2024-10-08 Felix Ott , David Rügamer , Lucas Heublein , Bernd Bischl , Christopher Mutschler

We propose a new learning method for heterogeneous domain adaptation (HDA), in which the data from the source domain and the target domain are represented by heterogeneous features with different dimensions. Using two different projection…

Machine Learning · Computer Science 2012-06-22 Lixin Duan , Dong Xu , Ivor Tsang

Object counting models suffer when deployed across domains with differing density variety, since density shifts are inherently task-relevant and violate standard domain adaptation assumptions. To address this, we propose a theoretical…

Computer Vision and Pattern Recognition · Computer Science 2025-11-03 Zhuonan Liang , Dongnan Liu , Jianan Fan , Yaxuan Song , Qiang Qu , Runnan Chen , Yu Yao , Peng Fu , Weidong Cai

Brain age estimation based on magnetic resonance imaging (MRI) is an active research area in early diagnosis of some neurodegenerative diseases (e.g. Alzheimer, Parkinson, Huntington, etc.) for elderly people or brain underdevelopment for…

Image and Video Processing · Electrical Eng. & Systems 2021-08-04 Ruizhe Li , Matteo Bastiani , Dorothee Auer , Christian Wagner , Xin Chen

Age dependent performance disparities in medical image classification often arise because age acts as a confounder, linking imaging morphology with disease prevalence. In practice, disparities can manifest as overdiagnosis at ages where…

Computer Vision and Pattern Recognition · Computer Science 2026-05-20 Nikhil Cherian Kurian , Victor Caquilpan Parra , Abin Shoby , Luke Whitbread , Lyle J. Palmer

Despite outstanding performance on public benchmarks, face recognition still suffers due to domain mismatch between training (source) and testing (target) data. Furthermore, these domains are not shared classes, which complicates domain…

Computer Vision and Pattern Recognition · Computer Science 2021-04-09 Chun-Hsien Lin , Bing-Fei Wu

Recent advances in unsupervised domain adaptation have shown the effectiveness of adversarial training to adapt features across domains, endowing neural networks with the capability of being tested on a target domain without requiring any…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Mikel Menta , Adriana Romero , Joost van de Weijer

Domain-invariant representation learning is a powerful method for domain generalization. Previous approaches face challenges such as high computational demands, training instability, and limited effectiveness with high-dimensional data,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Yuheng Xu , Taiping Zhang

We represent a process of learning by using bit strings, where 1-bits represent the knowledge acquired by individuals. Two ways of learning are considered: individual learning by trial-and-error; and social learning by copying knowledge…

Populations and Evolution · Quantitative Biology 2007-05-23 Armando Ticona Bustillos , Paulo Murilo C. de Oliveira

We introduce a novel unsupervised domain adaptation approach for object detection. We aim to alleviate the imperfect translation problem of pixel-level adaptations, and the source-biased discriminativity problem of feature-level adaptations…

Computer Vision and Pattern Recognition · Computer Science 2019-05-15 Taekyung Kim , Minki Jeong , Seunghyeon Kim , Seokeon Choi , Changick Kim

In DNA computing, it is impossible to decide whether a specific hybridization among complex DNA molecules is effective or not within acceptable time. In order to address this common problem, we introduce a new method based on the machine…

Quantitative Methods · Quantitative Biology 2018-07-03 Weijun Zhu

Survival analysis is the branch of statistics that studies the relation between the characteristics of living entities and their respective survival times, taking into account the partial information held by censored cases. A good analysis…

Machine Learning · Computer Science 2023-03-07 Ammar Shaker , Carolin Lawrence

Recent evidence highlights the usefulness of DNA methylation (DNAm) biomarkers as surrogates for exposure to risk factors for non-communicable diseases in epidemiological studies and randomized trials. DNAm variability has been demonstrated…

Applications · Statistics 2023-02-28 Andrea Cappozzo , Francesca Ieva , Giovanni Fiorito

Predicting drug response in patients from preclinical data remains a major challenge in precision oncology due to the substantial biological gap between in vitro cell lines and patient tumors. Rather than aiming to improve absolute in vitro…

Machine Learning · Computer Science 2026-03-18 Camille Jimenez Cortes , Philippe Lalanda , German Vega

A Deep Autoencoder based content retrieval algorithm is proposed for prediction and differentiation of cancer types based on the presence of epigenetic patterns of DNA methylation identified in genetic regions known as CpG islands. The…

Quantitative Methods · Quantitative Biology 2018-10-08 Mohammed Khwaja , Melpomeni Kalofonou , Chris Toumazou

In this work we propose a novel deep-learning approach for age estimation based on face images. We first introduce a dual image augmentation-aggregation approach based on attention. This allows the network to jointly utilize multiple face…

Computer Vision and Pattern Recognition · Computer Science 2023-09-29 Shakediel Hiba , Yosi Keller