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Diffraction-limited imaging in epi-fluorescence microscopy remains a challenge when sample aberrations are present or when the region of interest rests deep within an inhomogeneous medium. Adaptive optics is an attractive solution albeit…

In fluorescence microscopy, spectral unmixing aims to recover individual fluorophore concentrations from spectral images that capture mixed fluorophore emissions. Since classical methods operate pixel-wise and rely on least-squares fitting,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Federico Carrara , Talley Lambert , Mehdi Seifi , Florian Jug

Diffusion has been widely used to describe a random walk of particles or waves, and it requires only one parameter -- the diffusion constant. For waves, however, diffusion is an approximation that disregards the possibility of interference.…

Optics · Physics 2014-01-23 Alexey G. Yamilov , Raktim Sarma , Brandon Redding , Ben Payne , Heeso Noh , Hui Cao

In this work, we present and investigate the novel blind inverse problem of position-blind ptychography, i.e., ptychographic phase retrieval without any knowledge of scan positions, which then must be recovered jointly with the image. The…

Image and Video Processing · Electrical Eng. & Systems 2026-03-18 Simon Welker , Lorenz Kuger , Tim Roith , Berthy Feng , Martin Burger , Timo Gerkmann , Henry Chapman

The focus of this work is on rigorous mathematical analysis of the topological derivative based detection algorithms for the localization of an elastic inclusion of vanishing characteristic size. A filtered quadratic misfit is considered…

Analysis of PDEs · Mathematics 2012-11-29 Habib Ammari , Elie Bretin , Josselin Garnier , Wenjia Jing , Hyeonbae Kang , Abdul Wahab

Endomicroscopy is an emerging imaging modality, that facilitates the acquisition of in vivo, in situ optical biopsies, assisting diagnostic and potentially therapeutic interventions. While there is a diverse and constantly expanding range…

Computer Vision and Pattern Recognition · Computer Science 2020-01-01 Antonios Perperidis , Kevin Dhaliwal , Stephen McLaughlin , Tom Vercauteren

A holographic microscope captures interference patterns, or holograms, that encode three-dimensional (3D) information about the object being viewed. Computation is essential to extracting that 3D information. By wrapping low-level…

Image and Video Processing · Electrical Eng. & Systems 2018-06-04 Solomon Barkley , Thomas G. Dimiduk , Jerome Fung , David M. Kaz , Vinothan N. Manoharan , Ryan McGorty , Rebecca W. Perry , Anna Wang

The interference between radiation fields superposed appropriately contains all available information about the source. This will be recapitulated for coherent and incoherent fields. We will further analyze a new kind of twisted 3D…

Optics · Physics 2016-11-28 Martin Berz , Cordelia Berz

Optical diffraction tomography is an indispensable tool for studying objects in three-dimensions due to its ability to accurately reconstruct scattering objects. Until now this technique has been limited to coherent light because spatial…

Transmission electron diffraction is a powerful and versatile structural probe for the characterization of a broad range of materials, from nanocrystalline thin films to single crystals. With recent developments in fast electron detectors…

Materials Science · Physics 2021-10-06 Jian-Min Zuo , Renliang Yuan , Yu-Tsun Shao , Haw-Wen Hsiao , Saran Pidaparthy , Yang Hu , Qun Yang , Jiong Zhang

In non-destructive imaging the information about the spatial pattern of a samples interior has to be transferred to the sample surface by certain waves, e.g. ultrasound or electromagnetic waves. At the sample surface these waves can be…

Statistical Mechanics · Physics 2015-04-07 Peter Burgholzer

In this paper, we address the problem of plausible object placement for the challenging task of realistic image composition. We propose DiffPop, the first framework that utilizes plausibility-guided denoising diffusion probabilistic model…

Computer Vision and Pattern Recognition · Computer Science 2024-06-13 Jiacheng Liu , Hang Zhou , Shida Wei , Rui Ma

Cryo-electron microscopy (EM) single particle reconstruction is an entirely general technique for 3D structure determination of macromolecular complexes. However, because the images are taken at low electron dose, it is extremely hard to…

Computer Vision and Pattern Recognition · Computer Science 2019-04-17 Yifeng Fan , Zhizhen Zhao

Evanescent-wave microscopy achieves sub-diffraction axial sectioning by confining fluorescence excitation to a thin layer close to the cell/substrate interface. How thin this light sheet exactly is, however, is often unknown. Particularly…

Biological Physics · Physics 2013-02-08 Maia Brunstein , Maxime Teremetz , Christophe Tourain , Martin Oheim

Polarized light microscopy provides unique opportunities for analyzing the molecular order in man-made and natural materials, including biological structures inside living cells, tissues, and whole organisms. 20 years ago, the LC-PolScope…

Optics · Physics 2015-06-16 Shalin B. Mehta , Michael Shribak , Rudolf Oldenbourg

Photoelectron interferograms, manifested in photoelectron angular distributions (PADs), are a high-information, coherent observable. In order to obtain the maximum information from angle-resolved photoionization experiments it is desirable…

Atomic Physics · Physics 2015-07-22 P. Hockett , C. Lux , M. Wollenhaupt , T. Baumert

X-ray fluorescence holography (XFH) is a method for obtaining diffraction-limited images of the local atomic structure around a given type of emitter. The reconstructed wave-field represents a distorted image of the scatterer electron…

Condensed Matter · Physics 2009-09-29 S. Marchesini , C. S. Fadley , F. J. Garcia de Abajo

Jammed matter is by definition impenetrable to light, rendering the characterization of the 3D geometry difficult. Confocal microscopy of a dyed, refractive index matched emulsion nevertheless allows one to image the jammed system. Here we…

Soft Condensed Matter · Physics 2007-05-23 J. Brujic , G. Marty , C. Song , C. Briscoe , H. A. Makse

Ideal models of complex materials must satisfy all available information about the system. Generally, this information consists of experimental data, information implicit to sophisticated interatomic interactions and potentially other {\it…

Disordered Systems and Neural Networks · Physics 2009-11-13 Parthapratim Biswas , Raymond Atta-Fynn , S. Chakraborty , D. A. Drabold

Since manual object detection is very inaccurate and time consuming, some automatic object detection tools have been developed in recent years. At the moment, there is no image analysis software available which provides an automatic,…

Computer Vision and Pattern Recognition · Computer Science 2016-01-07 Ramin Norousi , Volker J. Schmid
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