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Growing evidence suggests that phase-locked deep brain stimulation (DBS) can effectively regulate abnormal brain connectivity in neurological and psychiatric disorders. This letter therefore presents a low-power SoC with both neural…

Systems and Control · Electrical Eng. & Systems 2023-03-21 Uisub Shin , Cong Ding , Virginia Woods , Alik S. Widge , Mahsa Shoaran

This work proposes a unified control architecture that couples a Reinforcement Learning (RL)-driven controller with a disturbance-rejection Extended State Observer (ESO), complemented by an Event-Triggered Mechanism (ETM) to limit…

Optimization and Control · Mathematics 2026-01-01 Ningwei Bai , Chi Pui Chan , Qichen Yin , Tengyang Gong , Yunda Yan , Zezhi Tang

Objective: The objective of this study is to develop and evaluate a systematic approach to optimize Deep Brain Stimulation (DBS) parameters, addressing the challenge of identifying patient-specific settings and optimal stimulation targets…

Systems and Control · Electrical Eng. & Systems 2026-01-13 Anna Franziska Frigge , Lina Uggla , Elena Jiltsova , Markus Fahlström , Dag Nyholm , Alexander Medvedev

Proptosis is characterized by a protrusion of the eyeball due to an increase of the orbital tissue volume. To recover a normal eyeball positioning, the most frequent surgical technique (BROD technique) consists in the osteotomy of orbital…

Medical Physics · Physics 2007-05-23 Vincent Luboz , Dominique Ambard , Franck Boutault , Pascal Swider , Yohan Payan

Over one third of the estimated 3 million people with epilepsy in the US are medication resistant. Responsive neurostimulation from chronically implanted electrodes provides a promising treatment option and alternative to resective surgery.…

Brain-computer interfaces (BCIs) use brain signals such as electroencephalography to reflect user intention and enable two-way communication between computers and users. BCI technology has recently received much attention in healthcare…

Human-Computer Interaction · Computer Science 2024-01-31 Byoung-Hee Kwon , Ji-Hoon Jeong , Seong-Whan Lee

Parkinsons disease (PD) is a debilitating motor system disorder characterized by progressive loss of movement, tremors, and speech slurring. PD is due to the loss of dopamine-producing brain cells, and symptoms only worsen over time, making…

Neurons and Cognition · Quantitative Biology 2014-05-07 Pooja Chandrashekar

We present a virtual reality (VR) experience that creates a research-grade benchmark in assessing patients with active upper-limb tremor, while simultaneously offering the opportunity for patients to engage with VR experiences without their…

Neurological disorders pose major global health challenges, driving advances in brain signal analysis. Scalp electroencephalography (EEG) and intracranial EEG (iEEG) are widely used for diagnosis and monitoring. However, dataset…

Neurons and Cognition · Quantitative Biology 2025-10-24 Jiahe Li , Xin Chen , Fanqi Shen , Junru Chen , Yuxin Liu , Daoze Zhang , Zhizhang Yuan , Fang Zhao , Meng Li , Yang Yang

Transcranial direct current stimulation (tDCS) is known to have a modulatory effect on neural tissue and that it is polarity specific. It is also shown that tDCS demonstrated the lasting effect in therapeutic applications. The main aim of…

Neurons and Cognition · Quantitative Biology 2018-12-05 Milena Cukic , Miodrag Stokic , Slavoljub Radenkovic , Milos Ljubisavljevic , Dragoljub Donald Pokrajac

Transcranial Electrical Stimulation (tES) is a neuromodulation technique that utilizes electrodes on the scalp to stimulate target brain regions. tES has shown promise in treating many neurological conditions, such as stroke rehabilitation…

Systems and Control · Electrical Eng. & Systems 2025-02-04 Chaitanya Goswami , Pulkit Grover

Identifying stimulus-driven neural activity patterns is critical for studying the neural basis of cognition. This can be particularly challenging in intracranial datasets, where electrode locations typically vary across patients. This…

Neurons and Cognition · Quantitative Biology 2022-02-07 Jeremy R. Manning

Peripheral Nerve Stimulation (PNS) constrains the clinical performance of Magnetic Resonance and Particle Imaging (MRI and MPI) systems. Extensive magneto-stimulation studies have been carried out recently in the field of MPI, where typical…

We present a quantitative study of phase entrainment by periodic visual stimuli in a biologically inspired neural network. The objective is to understand the neuronal population dynamics that underlie phase entrainment of brain oscillations…

Neurons and Cognition · Quantitative Biology 2021-11-16 Swapna Sasi , Basabdatta Sen Bhattacharya

Parkinson's Disease (PD) is a slowly evolving neuro-logical disease that affects about 1% of the population above 60 years old, causing symptoms that are subtle at first, but whose intensity increases as the disease progresses. Automated…

Spinal cord injury (SCI) is a debilitating condition that often results in significant motor and sensory deficits, impacting the quality of life. Current rehabilitation methods, including physical therapy and electrical stimulation, offer…

Neurons and Cognition · Quantitative Biology 2024-12-18 Ruidong Cheng , Yuling Shao , Xi Li , Li Zhang , Zehao Sheng , Chenyang Li , Xu Xie , Huilin Mou , Weidong Chen , Shaomin Zhang , Yuchen Xu , Minmin Wang

Epilepsy is the second most common brain disorder after migraine. Automatic detection of epileptic seizures can considerably improve the patients' quality of life. Current Electroencephalogram (EEG)-based seizure detection systems encounter…

Signal Processing · Electrical Eng. & Systems 2018-03-28 Ramy Hussein , Hamid Palangi , Rabab Ward , Z. Jane Wang

Sensory feedback is critical to the performance of neural prostheses that restore movement control after neurological injury. Recent advances in direct neural control of paralyzed arms present new requirements for miniaturized, low-power…

Small continuous sensory and mechanical perturbations have often been used to identify properties of the closed-loop neural control of posture and other systems that are approximately linear time invariant. Here we extend this approach to…

Neurons and Cognition · Quantitative Biology 2016-10-31 Tim Kiemel , David Logan , John J. Jeka

Tactile perception is an essential ability of intelligent robots in interaction with their surrounding environments. This perception as an intermediate level acts between sensation and action and has to be defined properly to generate…

Robotics · Computer Science 2019-07-24 Masoud Baghbahari , Aman Behal