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Physical therapy (PT) is a key component of many rehabilitation regimens, such as treatments for Parkinson's disease (PD). However, there are shortages of physical therapists and adherence to self-guided PT is low. Robots have the potential…

Here we describe an "information based exchange" model of brain function that ascribes to neocortex, basal ganglia, and thalamus distinct network functions. The model allows us to analyze whole brain system set point measures, such as the…

Neurons and Cognition · Quantitative Biology 2015-09-17 James Kozloski

The use of small amplitude electric currents delivered through the scalp, termed transcranial current stimulation (tCS, tDCS / tACS when using DC / AC currents) holds considerable promise for developing safe and effective treatments for…

Neurons and Cognition · Quantitative Biology 2024-10-10 Julien Modolo , Mengsen Zhang , Joan Duprez , Flavio Frohlich

We propose to fuse two currently separate research lines on novel therapies for stroke rehabilitation: brain-computer interface (BCI) training and transcranial electrical stimulation (TES). Specifically, we show that BCI technology can be…

A new type of non-invasive deep-brain stimulation is conceived and demonstrated by computer simulations. The process is based on spatio-temporal Fourier synthesis using multiple electrode pairs with sinusoidal current drive to limit skin…

General Physics · Physics 2024-08-02 Laszlo B. Kish , Andrea Antal

Introduction: Rehabilitation after a neurological impairment can be supported by functional electrical stimulation (FES). However, FES is limited by early muscle fatigue, slowing down the recovery progress. The use of optimal control to…

Medical Physics · Physics 2025-08-06 Kevin Co , Mickaël Begon , François Bailly , Florent Moissenet

Re-entry of travelling excitation loops is a long-suspected driver of human seizures, yet how such loops arise in patient brain networks -- and how susceptible they are to targeted disruption -- remains unclear. We reconstruct a…

Neurons and Cognition · Quantitative Biology 2025-08-08 Paul Triebkorn , Huifang E. Wang , Marmaduke Woodman , Maxime Guye , Fabrice Bartolomei , Viktor Jirsa

Parkinson's disease (PD) is a neurodegenerative disorder characterized by increased response times leading to a variety of biomechanical symptoms such as tremors, stooping and gait instability. Although the deterioration in biomechanical…

Quantitative Methods · Quantitative Biology 2017-07-27 Vrutangkumar Shah , Sachin Goyal , Harish Palanthandalam-Madapusi

Wearable robotics have the capacity to assist stroke survivors in assisting and rehabilitating hand function. Many devices that use surface electromyographic (sEMG) for control rely on extrinsic muscle signals, since sEMG sensors are…

Objectives: Permissible limits have been established by international guidelines and standards for human protection to electromagnetic field exposure to prevent adverse health effects stemming from electrostimulation in the most sensitive…

Medical Physics · Physics 2025-02-12 Jose Gomez-Tames , Thomas Tarnaud , Wout Joseph , Emmeric Tanghe

While the original goal for developing robots is replacing humans in dangerous and tedious tasks, the final target shall be completely mimicking the human cognitive and motor behaviour. Hence, building detailed computational models for the…

Robotics · Computer Science 2021-02-04 Omar Zahra , David Navarro-Alarcon , Silvia Tolu

Physical movement therapy is a crucial method of rehabilitation aimed at reinstating mobility among patients facing motor dysfunction due to neurological conditions or accidents. Such therapy is usually featured as patient-specific,…

Robotics · Computer Science 2024-12-06 Teng Li

Multiple sclerosis (MS) affects the central nervous system with a wide range of symptoms. MS can, for example, cause pain, changes in mood and fatigue, and may impair a person's movement, speech and visual functions. Diagnosis of MS…

Computers and Society · Computer Science 2020-12-03 Patrick Schwab , Walter Karlen

In this work, we explore the various Brain Neuron tracking techniques, which is one of the most significant applications of Diffusion Tensor Imaging. Tractography provides us with a non-invasive method to analyze underlying tissue…

Computer Vision and Pattern Recognition · Computer Science 2018-06-12 Nandakishore Puttashamachar , Ulas Bagci

A deep neural network (DNN) that can reliably model muscle responses from corresponding brain stimulation has the potential to increase knowledge of coordinated motor control for numerous basic science and applied use cases. Such cases…

Glioma cells can reshape functional neuronal networks by hijacking neuronal synapses, leading to partial or complete neurological dysfunction. These mechanisms have been previously explored for language functions. However, the impact of…

Closed-loop neural interfaces with on-chip machine learning can detect and suppress disease symptoms in neurological disorders or restore lost functions in paralyzed patients. While high-density neural recording can provide rich neural…

Signal Processing · Electrical Eng. & Systems 2023-03-21 Uisub Shin , Cong Ding , Bingzhao Zhu , Yashwanth Vyza , Alix Trouillet , Emilie C. M. Revol , Stéphanie P. Lacour , Mahsa Shoaran

Kalman filtering has proven to be effective for estimating brain activity using EEG recordings. In particular, the introduced post hoc standardization step of the algorithm, inspired by the sLORETA time-invariant method, reduces the depth…

Numerical Analysis · Mathematics 2025-11-17 Veikka Piispa , Dilshanie Prasikala , Joonas Lahtinen , Alexandra Koulouri , Sampsa Pursiainen

Majority of stroke survivors are left with poorly functioning paretic hands. Current rehabilitation devices have failed to motivate the patients enough to continue rehabilitation exercises. The objective of this project, MIDAS…

The level of challenge in stroke rehabilitation has to be carefully chosen to keep the patient engaged and motivated while not frustrating them. This paper presents a simulation where this level of challenge is automatically optimized using…

Systems and Control · Electrical Eng. & Systems 2021-06-08 Sandra-Carina Noble , Tomas Ward , John V. Ringwood