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We develop a multi-patch and multi-group model that captures the dynamics of an infectious disease when the host is structured into an arbitrary number of groups and interacts into an arbitrary number of patches where the infection takes…

Populations and Evolution · Quantitative Biology 2017-11-23 Derdei Bichara , Abderrahman Iggidr

Metapopulation models are commonly used in ecology, evolution, and epidemiology. These models usually entail homogeneity assumptions within patches and study networks of migration between patches to generate insights into conservation of…

Populations and Evolution · Quantitative Biology 2025-06-06 Diepreye Ayabina , Hasan Sevil , Adam Kleczkowski , M. Gabriela M. Gomes

Understanding the spatio-temporal evolution of epidemics with multiple pathogens requires not only new theoretical models but also careful analysis of their practical consequences. Building on the Multiplex Bi-Virus Reaction-Diffusion…

Physics and Society · Physics 2025-09-04 Alyssa Yu , Laura P. Schaposnik

This study is concerned with the dynamical behaviors of epidemic spreading over a two-layered interconnected network. Three models in different levels are proposed to describe cooperative spreading processes over the interconnected network,…

Physics and Society · Physics 2017-02-15 Xiang Wei , Xiaoqun Wu , Shihua Chen , Jun-an Lu , Guanrong Chen

A compartment epidemic model for infectious disease spreading is investigated, where movement of individuals is governed by spatial diffusion. The model includes infection age of the infected individuals and assumes a logistic growth of the…

Analysis of PDEs · Mathematics 2023-06-28 Christoph Walker

We analyse a model that describes the propagation of many pathogens within and between many species. A branching process approximation is used to compute the probability of disease outbreaks. Special cases of aquatic environments with two…

Populations and Evolution · Quantitative Biology 2026-05-21 Clotilde Djuikem , Julien Arino

There is a rich history of models for the interaction of a biological contagion like influenza with the spread of related information such as an influenza vaccination campaign. Recent work on the spread of interacting contagions on networks…

Physics and Society · Physics 2020-09-02 Laurent Hébert-Dufresne , Dina Mistry , Benjamin M. Althouse

Although traditional models of epidemic spreading focus on the number of infected, susceptible and recovered individuals, a lot of attention has been devoted to integrate epidemic models with population genetics. Here we develop an…

Populations and Evolution · Quantitative Biology 2021-11-24 Vitor M. Marquioni , Marcus A. M. de Aguiar

We present a model for obligated mutualistic associations, in which two transmissible diseases are allowed to infect just one population. As the general model proves too hard to be fully analytically investigated, some special cases are…

Populations and Evolution · Quantitative Biology 2014-03-03 Chiara Bosica , Alessandra De Rossi , Noemi L. Fatibene , Matteo Sciarra , Ezio Venturino

Epidemic spreading over populations networks has been an important subject of research for several decades, and especially during the Covid-19 pandemic. Most epidemic outbreaks are likely to create multiple mutations during their spreading…

Populations and Evolution · Quantitative Biology 2025-09-30 Aviel Ivry , Reuven Cohen , Amikam Patron

We present an analysis of six deterministic models for epidemic spreading. The evolution of the number of individuals of each class is given by ordinary differential equations of the first order in time, which are set up by using the laws…

Biological Physics · Physics 2020-12-25 Tânia Tomé , Mário J. de Oliveira

After more than 6 million deaths worldwide, the ongoing vaccination to conquer the COVID-19 disease is now competing with the emergence of increasingly contagious mutations, repeatedly supplanting earlier strains. Following the near-absence…

Populations and Evolution · Quantitative Biology 2022-05-09 Fabian Jan Schwarzendahl , Jens Grauer , Benno Liebchen , Hartmut Löwen

We introduce and investigate an SIS-type model for the spread of an infectious disease, where the infected population is structured with respect to the different strain of the virus/bacteria they are carrying. Our aim is to capture the…

Analysis of PDEs · Mathematics 2019-03-25 Àngel Calsina , József Z. Farkas

The propagations of diseases, behaviors and information in real systems are rarely independent of each other, but they are coevolving with strong interactions. To uncover the dynamical mechanisms, the evolving spatiotemporal patterns and…

Physics and Society · Physics 2019-10-02 Wei Wang , Quan-Hui Liu , Junhao Liang , Yanqing Hu , Tao Zhou

Mathematical models of infectious disease transmission typically neglect within-host dynamics. Yet within-host dynamics - including pathogen replication, host immune responses, and interactions with microbiota - are crucial not only for…

Populations and Evolution · Quantitative Biology 2023-12-20 Cameron A. Smith , Ben Ashby

Compartmental models are the most widely used framework for modeling infectious diseases. These models have been continuously refined to incorporate all the realistic mechanisms that can shape the course of an epidemic outbreak. Building on…

For a recently derived pairwise model of network epidemics with non-Markovian recovery, we prove that under some mild technical conditions on the distribution of the infectious periods, smaller variance in the recovery time leads to higher…

Populations and Evolution · Quantitative Biology 2018-12-27 Zsolt Vizi , István Z. Kiss , Joel C. Miller , Gergely Röst

In this paper, we study the problem of multiple change-point detection for a univariate sequence under the epidemic setting, where the behavior of the sequence alternates between a common normal state and different epidemic states. This is…

Methodology · Statistics 2021-01-07 Zifeng Zhao , Chun Yip Yau

The spatial structure of populations is a key element in the understanding of the large scale spreading of epidemics. Motivated by the recent empirical evidence on the heterogeneous properties of transportation and commuting patterns among…

Populations and Evolution · Quantitative Biology 2008-03-19 Vittoria Colizza , Alessandro Vespignani

The abrupt outbreak and transmission of biological diseases has always been a long-time concern of humankind. For long, mathematical modeling has served as a simple and yet efficient tool to investigate, predict, and control spread of…

Populations and Evolution · Quantitative Biology 2020-04-10 Aresh Dadlani , Richard O. Afolabi , Hyoyoung Jung , Khosrow Sohraby , Kiseon Kim