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This paper presents a compact pairwise model that describes the spread of multi-stage epidemics on networks. The multi-stage model corresponds to a gamma-distributed infectious period which interpolates between the classical Markovian…

Populations and Evolution · Quantitative Biology 2016-12-08 N. Sherborne , K. B. Blyuss , I. Z. Kiss

Coinfection is the process by which a host that is infected with a pathogen becomes infected by a second pathogen at a later point in time. An immunosuppressant host response to a primary disease can facilitate spreading of a subsequent…

Physics and Society · Physics 2021-04-14 Peter Mann , Anne Smith , John Mitchell , Simon Dobson

Infectious disease modeling is used to forecast epidemics and assess the effectiveness of intervention strategies. Although the core assumption of mass-action models of homogeneously mixed population is often implausible, they are…

Physics and Society · Physics 2024-08-29 Thien-Minh Le , Jukka-Pekka Onnela

Infectious diseases are caused by pathogenic microorganisms and can spread through different ways. Mathematical models and computational simulation have been used extensively to investigate the transmission and spread of infectious…

In this paper, we propose a realistic mathematical model taking into account the mutual interference among the interacting populations. This model attempts to describe the control (vaccination) function as a function of the number of…

Neural and Evolutionary Computing · Computer Science 2016-11-18 V. Sree Hari Rao , M. Naresh Kumar

Understanding the interplay between human behavioral phenomena and infectious disease dynamics has been one of the central challenges of mathematical epidemiology. However, socio-cognitive processes critical for the initiation of desired…

Physics and Society · Physics 2024-01-01 Qingchu Wu , Tarik Hadzibeganovic , Xiao-Pu Han

The immune response to a pathogen has two basic features. The first is the expansion of a few pathogen-specific cells to form a population large enough to control the pathogen. The second is the process of differentiation of cells from an…

Populations and Evolution · Quantitative Biology 2014-02-04 Sean P Stromberg , Rustom Antia , Ilya Nemenman

We consider a multi-species reaction-diffusion system that arises in epidemiology to describe the spread of several strains, or variants, of a disease in a population. Our model is a natural spatial, multi-species, extension of the…

Analysis of PDEs · Mathematics 2022-08-02 Romain Ducasse , Samuel Nordmann

Modeling epidemic dynamics plays an important role in studying how diseases spread, predicting their future course, and designing strategies to control them. In this letter, we introduce a model of SIR (susceptible-infected-removed) type…

Populations and Evolution · Quantitative Biology 2013-12-17 Li Chen , Fakhteh Ghanbarnejad , Weiran Cai , Peter Grassberger

We investigate a discrete-time two-strain symbiotic epidemic model on complex networks with both random and long-range interactions. Our analysis examines how the co-infection recovery rate ($\mu$), the long-range decay exponent ($\alpha$),…

Physics and Society · Physics 2025-09-23 Frank Namugera

We consider the spread of infectious disease through contact networks of Configuration Model type. We assume that the disease spreads through contacts and infected individuals recover into an immune state. We discuss a number of existing…

Populations and Evolution · Quantitative Biology 2014-03-11 Joel C Miller , Istvan Z Kiss

Epidemic spreading has been studied for a long time and most of them are focused on the growing aspect of a single epidemic outbreak. Recently, we extended the study to the case of recurrent epidemics (Sci. Rep. {\bf 5}, 16010 (2015)) but…

Physics and Society · Physics 2017-05-29 Muhua Zheng , Ming Zhao , Byungjoon Min , Zonghua Liu

We formulate a compartmental model for the propagation of a respiratory disease in a patchy environment. The patches are connected through the mobility of individuals, and we assume that disease transmission and recovery are possible during…

Populations and Evolution · Quantitative Biology 2021-10-11 Indrajit Ghosh , Sk Shahid Nadim , Soumyendu Raha , Debnath Pal

Interactions among multiple infectious agents are increasingly recognized as a fundamental issue in the understanding of key questions in public health, regarding pathogen emergence, maintenance, and evolution. The full description of…

Populations and Evolution · Quantitative Biology 2013-08-21 Chiara Poletto , Sandro Meloni , Vittoria Colizza , Yamir Moreno , Alessandro Vespignani

Evidence-informed policy on infections requires estimates of their effects on health. However, pathogenic variation, whereby occurrence of adverse outcomes depends on the infecting strain, might complicate the study of many infectious…

Methodology · Statistics 2026-04-24 Bronner P. Gonçalves

Early estimates of the transmission potential of emerging and re-emerging infections are increasingly used to inform public health authorities on the level of risk posed by outbreaks. Existing methods to estimate the reproduction number…

Quantitative Methods · Quantitative Biology 2016-10-10 Gerardo Chowell , Cécile Viboud , Lone Simonsen , Seyed Moghadas

We develop a new structured compartmental model for the coevolutionary dynamics between susceptible and infectious individuals in heterogeneous SI epidemiological systems. In this model, the susceptible compartment is structured by a…

Populations and Evolution · Quantitative Biology 2024-10-10 Tommaso Lorenzi , Elisa Paparelli , Andrea Tosin

In this work we consider an epidemic system modelling the evolution of a spore-producing pathogen within a multi-host population of plants. Here we focus our analysis on the study of the stationary states. We first discuss the existence of…

Analysis of PDEs · Mathematics 2020-08-03 Jean-Baptiste Burie , Arnaud Ducrot , Quentin Griette , Quentin Richard

Starting from common assumptions, we build a rate equation model for multi-strain disease dynamics in terms of immune repertoire classes. We then move to a strain-level description where a low-order closure reminiscent of a pair…

Populations and Evolution · Quantitative Biology 2014-04-09 Tomás Aquino , Diogo Bolster , Ana Nunes

Human diseases spread over networks of contacts between individuals and a substantial body of recent research has focused on the dynamics of the spreading process. Here we examine a model of two competing diseases spreading over the same…

Physics and Society · Physics 2015-03-19 Brian Karrer , M. E. J. Newman