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This paper proposes discomfort as a new material for HCI researchers and designers to consider in any application that helps a person develop a new skill, practice or state. Discomfort is a fundamental precursor of adaptation and adaptation…

Human-Computer Interaction · Computer Science 2021-05-11 m. c. schraefel , Michael Jones

Recent research revealed a considerable lack of reliability for user feedback when interacting with adaptive systems, often denoted as user noise or human uncertainty. Moreover, this lack of reliability holds striking impacts for the…

Human-Computer Interaction · Computer Science 2018-05-01 Kevin Jasberg , Sergej Sizov

Emergence is a phenomenon taken for granted in science but also still not well understood. We have developed a model of artificial genetic evolution intended to allow for emergence on genetic, population and social levels. We present the…

Populations and Evolution · Quantitative Biology 2015-05-19 Chris Marriott , Jobran Chebib

Computational models of neurodegeneration aim to emulate the evolving pattern of pathology in the brain during neurodegenerative disease, such as Alzheimer's disease. Previous studies have made specific choices on the mechanisms of…

Quantitative Methods · Quantitative Biology 2023-08-11 Tiantian He , Elinor Thompson , Anna Schroder , Neil P. Oxtoby , Ahmed Abdulaal , Frederik Barkhof , Daniel C. Alexander

This paper reports nano-CT analysis of brain tissues of schizophrenia and control cases. The analysis revealed that: (1) neuronal structures vary between individuals, (2) the mean curvature of distal neurites of the schizophrenia cases was…

Autonomous morphology, such as inflection class systems and paradigmatic distribution patterns, is widespread and diachronically resilient in natural language. Why this should be so has remained unclear given that autonomous morphology…

Computation and Language · Computer Science 2024-11-07 Erich Round , Louise Esher , Sacha Beniamine

Presented theory of feelings and emotions is based on Nonlinear Dynamics and Theory of Complex Systems. The most important assumption is that the brain may be considered to be composed of subsystems characterized by different characteristic…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 W. Klonowski

Precision medicine has received attention both in and outside the clinic. We focus on the latter, by exploiting the relationship between individuals' social interactions and their mental health to develop a predictive model of one's…

Social and Information Networks · Computer Science 2019-08-08 Shikang Liu , David Hachen , Omar Lizardo , Christian Poellabauer , Aaron Striegel , Tijana Milenkovic

While human beings have a right to digital experiences that support, rather than diminish, their psychological wellbeing, technology designers lack research-based practices for ensuring psychological needs are met. To help address this gap,…

Human-Computer Interaction · Computer Science 2022-08-24 Dorian Peters

Major Depressive Disorder (MDD) is a highly prevalent mental health condition, and a deeper understanding of its neurocognitive foundations is essential for identifying how core functions such as emotional and self-referential processing…

Mental health is not a fixed trait but a dynamic process shaped by the interplay between individual dispositions and situational contexts. Building on interactionist and constructionist psychological theories, we develop interpretable…

Computation and Language · Computer Science 2026-03-09 Nikita Soni , August Håkan Nilsson , Syeda Mahwish , Vasudha Varadarajan , H. Andrew Schwartz , Ryan L. Boyd

This paper introduces a new modeling perspective in the public mental health domain to provide a robust interpretation of the relations between anxiety and depression, and the demographic and temporal factors. This perspective particularly…

Applications · Statistics 2026-01-30 Mustafa Cavus , Przemysław Biecek , Julian Tejada , Fernando Marmolejo-Ramos , Andre Faro

The COVID-19 pandemic has forced many people to limit their social activities, which has resulted in a rise in mental illnesses, particularly depression. To diagnose these illnesses with accuracy and speed, and prevent severe outcomes such…

Machine Learning · Computer Science 2023-11-14 Hossein Simchi , Samira Tajik

Major Depressive Disorder is one of the leading causes of disability worldwide, yet its diagnosis still depends largely on subjective clinical assessments. Integrating Artificial Intelligence (AI) holds promise for developing objective,…

Artificial Intelligence · Computer Science 2026-05-01 Dorsa Macky Aleagha , Payam Zohari , Mostafa Haghir Chehreghani

Digital phenotyping is a nascent multidisciplinary field that has the potential to revolutionize psychiatry and its clinical practice. In this paper, we present a rigorous statistical analysis of short-time features extracted from wearable…

Background: Depression is a major public health concern, affecting an estimated five percent of the global population. Early and accurate diagnosis is essential to initiate effective treatment, yet recognition remains challenging in many…

Signal Processing · Electrical Eng. & Systems 2025-11-21 Jana Weber , Marcel Weber , Juan Miguel Lopez Alcaraz

Current artificial intelligence systems struggle with systematic compositional reasoning: the capacity to recombine known components in novel configurations. This paper argues that the failure is architectural, not merely a matter of scale…

Computation and Language · Computer Science 2026-04-15 Alex Anvi Eponon , Ildar Batyrshin , Christian E. Maldonado-Sifuentes , Grigori Sidorov

The recent phenomenal success of language models has reinvigorated machine learning research, and large sequence models such as transformers are being applied to a variety of domains. One important problem class that has remained relatively…

Statistical mechanics determines the abundance of different arrangements of matter depending on cost-benefit balances. Its formalism and phenomenology percolate throughout biological processes and set limits to effective computation. Under…

Neurons and Cognition · Quantitative Biology 2021-02-03 Luís F Seoane

Noise plays a fundamental role in a wide variety of physical and biological dynamical systems. It can arise from an external forcing or due to random dynamics internal to the system. It is well established that even weak noise can result in…

Analysis of PDEs · Mathematics 2019-08-06 Eric Forgoston , Richard O. Moore