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The double empathy problem recasts the difficulty of forming empathy bonds in social interactions between autistic and neurotypical individuals as a bidirectional problem, rather than due to a deficit exclusive to the person on the…
Humans and other organisms make decisions choosing between different options, with the aim to maximize the reward and minimize the cost. The main theoretical framework for modeling the decision-making process has been based on the highly…
Depression is a leading cause of disability worldwide, but is often under-diagnosed and under-treated. One of the tenets of cognitive-behavioral therapy (CBT) is that individuals who are depressed exhibit distorted modes of thinking,…
We present a framework for characterizing neurosis in embodied AI: behaviors that are internally coherent yet misaligned with reality, arising from interactions among planning, uncertainty handling, and aversive memory. In a grid navigation…
We introduce a statistical agent based model to describe the phenomenon of drug abuse and its dynamical evolution at the individual and global level. The agents are heterogeneous with respect to their intrinsic inclination to drugs, to…
The underlying processes that enable self-perception are crucial for understanding multisensory integration, body perception and action, and the development of the self. Previous computational models have overlooked an essential aspect:…
How subjective experience (i.e., consciousness) arises out of objective material processes has been called the hard problem. The neuroscience of consciousness has set out to find the sufficient conditions for consciousness and theoretical…
Background: The choice of efficient antipsychotic therapy for schizophrenia relies on a time-consuming trial-and-error approach, whereas the social and economic burdens of the disease call for faster alternatives. Material \& methods: In a…
Neural network oscillations are a fundamental mechanism for cognition, perception and consciousness. Consequently, perturbations of network activity play an important role in the pathophysiology of brain disorders. When structural…
The diversity of cognitive deficits and neuropathological processes associated with dementias has encouraged divergence in pathophysiological explanations of disease. Here, we review an alternative framework that emphasises convergent…
It is generally recognized that a distinguishing feature of life is its peculiar capability to avoid equilibration. The origin of this capability and its evolution along the timeline of abiogenesis is not yet understood. We propose to study…
Different theories posit different sources for feelings of well-being and happiness. Appraisal theory grounds our emotional responses in our goals and desires and their fulfillment, or lack of fulfillment. Self Determination theory posits…
This study focuses on how different modalities of human communication can be used to distinguish between healthy controls and subjects with schizophrenia who exhibit strong positive symptoms. We developed a multi-modal schizophrenia…
Mental disorders such as depression and suicidal ideation are hazardous, affecting more than 300 million people over the world. However, on social media, mental disorder symptoms can be observed, and automated approaches are increasingly…
Acquiring fear responses to predictors of aversive outcomes is crucial for survival. At the same time, it is important to be able to modify such associations when they are maladaptive, for instance in treating anxiety and trauma-related…
Idiosyncratic tendency to choose one alternative over others in the absence of an identified reason, is a common observation in two-alternative forced-choice experiments. It is tempting to account for it as resulting from the (unknown)…
Density functional theory (DFT) exploits an independent-particle-system construction to replicate the densities and current of an interacting system. This construction is used here to access the exact effective potential and bias of…
Meditation is a family of mental practices that encompasses a wide array of techniques employing distinctive mental strategies. We systematically reviewed 78 functional neuroimaging (fMRI and PET) studies of meditation, and used activation…
A survival model is derived from the exponential function using the concept of fractional differentiation. The hazard function of the proposed model generates various shapes of curves including increasing, increasing-constant-increasing,…
Humans dispose of two intertwined information processing pathways, cognitive information processing via neural firing patterns and diffusive volume control via neuromodulation. The cognitive information processing in the brain is…