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Compartmental models, especially the Susceptible-Infected-Removed (SIR) model, have long been used to understand the behaviour of various diseases. Allowing parameters, such as the transmission rate, to be time-dependent functions makes it…

Methodology · Statistics 2024-09-27 Son Luu , Edward Susko , Lam Si Tung Ho

A stochastic SIR (susceptible $\to$ infective $\to$ recovered) epidemic model defined on a social network is analysed. The underlying social network is described by an Erd\H{o}s-R\'{e}nyi random graph but, during the course of the epidemic,…

Probability · Mathematics 2020-08-17 Frank Ball , Tom Britton

Assessing the practical identifiability of epidemic models is essential for determining whether parameters can be meaningfully estimated from observed data. Monte Carlo (MC) methods provide an accessible and intuitive framework; however,…

Methodology · Statistics 2025-10-01 Chiara Mattamira , Olivia Prosper Feldman

Modelling the transmission dynamics of an infectious disease is a complex task. Not only it is difficult to accurately model the inherent non-stationarity and heterogeneity of transmission, but it is nearly impossible to describe,…

Computation · Statistics 2023-07-19 Sanmitra Ghosh , Paul J. Birrell , Daniela De Angelis

We consider a broad class of continuous-time two-type population size-dependent Markov Branching Processes. The offspring distribution can depend on the current (alive) and total (dead and alive) populations. Using stochastic approximation…

Probability · Mathematics 2023-04-04 Khushboo Agarwal , Veeraruna Kavitha

Epidemic models currently play a central role in our attempts to understand and control infectious diseases. Here, we derive a model for the diffusion limit of stochastic susceptible-infectious-removed (SIR) epidemic dynamics on a…

Populations and Evolution · Quantitative Biology 2013-09-30 Matthew Graham , Thomas House

The COVID-19 pandemic has been characterised by multiple waves of transmission driven by interventions and emerging variants, challenging epidemic models that assume gradually evolving transmission dynamics. We propose a class of…

Applications · Statistics 2026-05-05 Patrick Aschermayr , Konstantinos Kalogeropoulos , Nikolaos Demiris

Renewal models are widely used in statistical epidemiology as semi-mechanistic models of disease transmission. While primarily used for estimating the instantaneous reproduction number, they can also be used for generating projections,…

Methodology · Statistics 2025-09-25 Nicholas Steyn , Kris V. Parag , Robin N. Thompson , Christl A. Donnelly

State-space models have been widely used to model the dynamics of communicable diseases in populations of interest by fitting to time-series data. Particle filters have enabled these models to incorporate stochasticity and so can better…

Applications · Statistics 2022-05-17 Conor Rosato , John Harris , Jasmina Panovska-Griffiths , Simon Maskell

Mathematical models are formal and simplified representations of the knowledge related to a phenomenon. In classical epidemic models, a neglected aspect is the heterogeneity of disease transmission and progression linked to the viral load…

Physics and Society · Physics 2022-05-10 Rossella Della Marca , Nadia Loy , Andrea Tosin

Doubly intractable distributions arise in many settings, for example in Markov models for point processes and exponential random graph models for networks. Bayesian inference for these models is challenging because they involve intractable…

Computation · Statistics 2019-04-03 Jaewoo Park , Murali Haran

Bayesian inference methods are useful in infectious diseases modeling due to their capability to propagate uncertainty, manage sparse data, incorporate latent structures, and address high-dimensional parameter spaces. However, parameter…

Methodology · Statistics 2025-04-29 Xiahui Li , Fergus Chadwick , Ben Swallow

This paper develops an individual-based stochastic network SIR model for the empirical analysis of the Covid-19 pandemic. It derives moment conditions for the number of infected and active cases for single as well as multigroup epidemic…

Econometrics · Economics 2022-01-05 M. Hashem Pesaran , Cynthia Fan Yang

Using the continuous-time susceptible-infected-susceptible (SIS) model on networks, we investigate the problem of inferring the class of the underlying network when epidemic data is only available at population-level (i.e. the number of…

Populations and Evolution · Quantitative Biology 2019-12-05 F. Di Lauro , J. -C. Croix , M. Dashti , L. Berthouze , I. Z. Kiss

We present a new Bayesian inference method for compartmental models that takes into account the intrinsic stochasticity of the process. We show how to formulate a SIR-type Markov jump process as the solution of a stochastic differential…

Methodology · Statistics 2020-04-23 Benjamin Nguyen-Van-Yen , Pierre Del Moral , Bernard Cazelles

Epidemic propagation on networks represents an important departure from traditional massaction models. However, the high-dimensionality of the exact models poses a challenge to both mathematical analysis and parameter inference. By using…

Quantitative Methods · Quantitative Biology 2023-02-07 István Z. Kiss , Luc Berthouze , Wasiur R. KhudaBukhsh

The Bayesian analysis of infectious disease surveillance data from multiple locations typically involves building and fitting a spatio-temporal model of how the disease spreads in the structured population. Here we present new generally…

Methodology · Statistics 2025-03-04 Matthew Adeoye , Xavier Didelot , Simon EF Spencer

The acute phase of the Covid-19 pandemic has made apparent the need for decision support based upon accurate epidemic modeling. This process is substantially hampered by under-reporting of cases and related data incompleteness issues. In…

Applications · Statistics 2026-03-10 Anastasios Apsemidis , Nikolaos Demiris

Many disease models focus on characterizing the underlying transmission mechanism but make simple, possibly naive assumptions about how infections are reported. In this note, we use a simple deterministic Susceptible-Infected-Removed (SIR)…

Populations and Evolution · Quantitative Biology 2019-11-28 Sang Woo Park , Benjamin M. Bolker

In the simple mean-field SIS and SIR epidemic models, infection is transmitted from infectious to susceptible members of a finite population by independent $p-$coin tosses. Spatial variants of these models are proposed, in which finite…

Probability · Mathematics 2009-09-29 Steven P. Lalley
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