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The Secondary Attack Rate (SAR) is a measure of how infectious a communicable disease is, and is often estimated based on studies of disease transmission in households. The Chain Binomial model is a simple model for disease outbreaks, and…

We propose a novel approach to perform approximate Bayesian inference in complex models such as Bayesian neural networks. The approach is more scalable to large data than Markov Chain Monte Carlo, it embraces more expressive models than…

Machine Learning · Statistics 2022-09-07 Joel Janek Dabrowski , Daniel Edward Pagendam

In this paper, we propose a realistic mathematical model taking into account the mutual interference among the interacting populations. This model attempts to describe the control (vaccination) function as a function of the number of…

Neural and Evolutionary Computing · Computer Science 2016-11-18 V. Sree Hari Rao , M. Naresh Kumar

Multiple-type branching processes that model the spread of infectious diseases are investigated. In these stochastic processes, the disease goes through multiple stages before it eventually disappears. We mostly focus on the critical…

Populations and Evolution · Quantitative Biology 2015-06-04 Tibor Antal , P. L. Krapivsky

Using Markov chain Monte Carlo to sample from posterior distributions was the key innovation which made Bayesian data analysis practical. Notoriously, however, MCMC is hard to tune, hard to diagnose, and hard to parallelize. This…

Computation · Statistics 2022-03-18 Cosma Rohilla Shalizi

Increasingly complex applications involve large datasets in combination with non-linear and high dimensional mathematical models. In this context, statistical inference is a challenging issue that calls for pragmatic approaches that take…

Data Analysis, Statistics and Probability · Physics 2013-01-31 Andreas Raue , Clemens Kreutz , Fabian Joachim Theis , Jens Timmer

Epidemic spread on networks is one of the most studied dynamics in network science and has important implications in real epidemic scenarios. Nonetheless, the dynamics of real epidemics and how it is affected by the underline structure of…

Physics and Society · Physics 2020-09-08 Bnaya Gross , Shlomo Havlin

We present a methodology providing a one-directional link from within-host individual heterogeneity to population-level disease transmission dynamics. The methodology works in several steps. A within-host model is investigated numerically…

Populations and Evolution · Quantitative Biology 2026-05-19 Julien Arino , Morgan Craig , Clotilde Djuikem , Kang-Ling Liao , Stéphanie Portet

An epidemic model where disease transmission can occur either through global contacts or through local, nearest neighbor interactions is considered. The classical SIR--model describing the global interactions is extended by adding…

Populations and Evolution · Quantitative Biology 2022-02-02 Thomas Götz

Estimating model parameters of a general family of cure models is always a challenging task mainly due to flatness and multimodality of the likelihood function. In this work, we propose a fully Bayesian approach in order to overcome these…

Methodology · Statistics 2024-08-20 Panagiotis Papastamoulis , Fotios Milienos

This paper studies the spread dynamics of a stochastic SIRS epidemic model with nonlinear incidence and varying population size, which is formulated as a piecewise deterministic Markov process. A threshold dynamic determined by the basic…

Dynamical Systems · Mathematics 2017-10-26 Dan Li , Shengqiang Liu , Jing'an Cui

Markov chains are a natural and well understood tool for describing one-dimensional patterns in time or space. We show how to infer $k$-th order Markov chains, for arbitrary $k$, from finite data by applying Bayesian methods to both…

Statistics Theory · Mathematics 2009-11-13 Christopher C. Strelioff , James P. Crutchfield , Alfred W. Hubler

The analysis of data from multiple experiments, such as observations of several individuals, is commonly approached using mixed-effects models, which account for variation between individuals through hierarchical representations. This makes…

Computation · Statistics 2026-03-05 Henrik Häggström , Sebastian Persson , Marija Cvijovic , Umberto Picchini

Throughout human history, epidemics have been a constant presence. Understanding their dynamics is essential to predict scenarios and make substantiated decisions. Mathematical models are powerful tools to describe an epidemic behavior.…

Systems and Control · Electrical Eng. & Systems 2024-07-26 Walter HMendes aselein , Diego Eckhard

Mechanistic mathematical models of within-host viral dynamics are tools for understanding how a virus' biology and its interaction with the immune system shape the infectivity of a host. The biology of the process is encoded by the…

Applications · Statistics 2025-12-11 Dylan J. Morris , Lauren Kennedy , Andrew J. Black

Stochastic reaction network models are often used to explain and predict the dynamics of gene regulation in single cells. These models usually involve several parameters, such as the kinetic rates of chemical reactions, that are not…

Computation · Statistics 2020-01-07 Thomas A. Catanach , Huy D. Vo , Brian Munsky

We predict the future course of ongoing susceptible-infected-susceptible (SIS) epidemics on regular, Erd\H{o}s-R\'{e}nyi and Barab\'asi-Albert networks. It is known that the contact network influences the spread of an epidemic within a…

Populations and Evolution · Quantitative Biology 2021-11-11 Tanja Zerenner , Francesco Di Lauro , Masoumeh Dashti , Luc Berthouze , Istvan Z. Kiss

Malware attacks in today's vast digital ecosystem pose a serious threat. Understanding malware propagation dynamics and designing effective control strategies are therefore essential. In this work, we propose a generic SEIRV model…

Cryptography and Security · Computer Science 2026-03-05 Samiran Ghosh , V Anil Kumar

Markov chain Monte Carlo methods are often deemed too computationally intensive to be of any practical use for big data applications, and in particular for inference on datasets containing a large number $n$ of individual data points, also…

Methodology · Statistics 2015-05-13 Rémi Bardenet , Arnaud Doucet , Chris Holmes

In this work, we review the figures used to characterize an epidemic outbreak most. Particular attention is drawn to epidemic spreading at time-varying transition rates. A time-varying SIR-like model is used to describe the epidemic…

Populations and Evolution · Quantitative Biology 2020-11-06 Hernán De Battista , José García-Clúa , Sebastián Nuñez , Fernando Inthamoussou , Fabricio Garelli