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A distributed optimal control problem for a diffuse interface model, which physical context is that of tumour growth dynamics, is addressed. The system we deal with comprises a Cahn--Hilliard equation for the tumour fraction coupled with a…

Analysis of PDEs · Mathematics 2021-01-20 Andrea Signori

We study the possibility to stabilize unstable steady states and unstable periodic orbits in chaotic fractional-order dynamical systems by the time-delayed feedback method. By performing a linear stability analysis, we establish the…

General Physics · Physics 2011-07-07 Aleksandar Gjurchinovski , Trifce Sandev , Viktor Urumov

We consider a stochastic optimal control problem governed by a stochastic differential equation with delay in the control. Using a result of existence and uniqueness of a sufficiently regular mild solution of the associated…

Probability · Mathematics 2021-03-22 F. Gozzi , F. Masiero

Active agents with time-delayed interactions arise naturally in various real-world systems, such as biological systems, transportation networks and robotic swarms. Such systems are typically modeled as Delay Differential Equations (DDEs)…

Dynamical Systems · Mathematics 2025-09-03 Yu Wang , Andreas Amann , Jinde Cao , Jürgen Kurths , Serhiy Yanchuk

The elapsed-time model describes the behavior of interconnected neurons through the time since their last spike. It is an age-structured non-linear equation in which age corresponds to the elapsed time since the last discharge, and models…

Dynamical Systems · Mathematics 2025-04-28 María J. Cáceres , José A Cañizo , Nicolas Torres

In this paper we consider the stability of a class of deterministic and stochastic SEIRS epidemic models with delay. Indeed, we assume that the transmission rate could be stochastic and the presence of a latency period of $r$ consecutive…

Probability · Mathematics 2017-02-22 Xavier Bardina , Marco Ferrante , Carles Rovira

This paper, which is the natural continuation of a previous paper by the same authors, studies a class of optimal control problems with state constraints where the state equation is a differential equation with delays. This class includes…

Optimization and Control · Mathematics 2009-07-10 Salvatore Federico , Ben Goldys , Fausto Gozzi

This paper explores a number of questions regarding optimal strategies evolved by viruses upon entry into a vertebrate host. The infected cell life cycle consists of a non-productively infected stage in which it is producing virions but not…

Cell Behavior · Quantitative Biology 2016-02-09 Soumya Banerjee

The sterile insect technique controls mosquito-borne diseases such as malaria, dengue, and yellow fever through either eradication or depressing the associated vector population. We formulate a three-dimensional delayed mosquito population…

Dynamical Systems · Mathematics 2025-09-23 Ruqaya Hussein , Sergey Kryzhevich , Khosro Tajbakhsh

In this article, we consider a cooperative control problem involving a heterogeneous network of dynamically decoupled continuous-time linear plants. The (output-feedback) controllers for each plant may communicate with each other according…

Optimization and Control · Mathematics 2024-01-09 Mruganka Kashyap , Laurent Lessard

This article proposes a non-autonomous mathematical model with delay for confrontation between two countries, and examines the stability of its equilibrium state. Our criteria for stability take into account the influence of the factor of…

Dynamical Systems · Mathematics 2026-05-14 Teresa Faria , Anatoliy A. Martynyuk

We study the problem of periodic event-triggered control of interconnected port-Hamiltonian systems subject to time-varying delays in their communication. In particular, we design a threshold parameter for the event-triggering condition, a…

Systems and Control · Electrical Eng. & Systems 2022-07-14 Ernesto Aranda-Escolástico , Leonardo J. Colombo , María Guinaldo , Antonio Visioli

The activation of a specific immune response takes place in the lymphoid organs such as the spleen. We present here a simplified model of the proliferation of specific immune cells in the form of a single delay equation. We show that the…

Dynamical Systems · Mathematics 2010-07-02 Angela Gallegos , Ami Radunskaya

In this paper, a mathematical model of pneumococcal pneumonia with time delays is proposed. The stability theory of delay differential equations is used to analyze the model. The results show that the disease-free equilibrium is…

Populations and Evolution · Quantitative Biology 2019-01-16 Fulgensia Kamugisha Mbabazi , Joseph Y. T. Mugisha , Mark Kimathi

This paper studies a distributed continuous-time bi-virus model in which two competing viruses spread over a network consisting of multiple groups of individuals. Limiting behaviors of the network are characterized by analyzing the…

Optimization and Control · Mathematics 2019-01-04 Ji Liu , Philip E. Pare , Angelia Nedich , Choon Yik Tang , Carolyn L. Beck , Tamer Basar

The stabilization of uncertain LTI/LPV time delay systems with time varying delays by state-feedback controllers is addressed. At the difference of other works in the literature, the proposed approach allows for the synthesis of resilient…

Systems and Control · Computer Science 2012-04-06 Corentin Briat , Olivier Sename , Jean-François Lafay

The aim of this paper is to provide a rigorous mathematical analysis of an optimal control problem with SIR dynamics. The main feature of our study is the presence of state constraints (related to intensive care units ICU capacity) and…

Optimization and Control · Mathematics 2021-08-25 Florin Avram , Lorenzo Freddi , Dan Goreac

This article considers the optimal control of the SIR model with both transmission and treatment uncertainty. It follows the model presented in Gatto and Schellhorn (2021). We make four significant improvements on the latter paper. First,…

Optimization and Control · Mathematics 2021-05-20 Yujia Ding , Henry Schellhorn

The concentration of CD4 T-lymphocytes (CD4 count), in a person's plasma is widely used to decide when to start HIV-positive people on anti-retroviral therapy (ART) and to predict the impact of ART on the future course of HIV and…

Quantitative Methods · Quantitative Biology 2013-01-08 Brian Williams , Eleanor Gouws

This paper is concerned with the problem of robust reliable control for a class of uncertain 2D discrete switched systems with state delays represented by a model of Roesser type. The parameter uncertainties are assumed to be norm-bounded.…

Dynamical Systems · Mathematics 2012-10-10 Shipei Huang , Zhengrong Xiang