Related papers: Evanescent single-molecule biosensing with quantum…
Significance: Superconducting nanowire single-photon detectors (SNSPDs; also known as SSPDs) show enormous promise for low-light biomedical imaging by offering exceptional sensitivity, picosecond timing resolution, and broad spectral…
Optical metasurface has brought a revolution in label-free molecular sensing, attracting extensive attention. Currently, such sensing approaches are being designed to respond to peak wavelengths with a higher Q factor in the visible and…
Recovering both amplitude and phase information from a system is a fundamental goal of optical imaging. At the same time, it is crucial to operate at low photon doses to avoid altering the sample, particularly in biological applications.…
A general quantum limit to the sensitivity of particle position measurements is derived following the simple principle of the Heisenberg microscope. The value of this limit is calculated for particles in the Rayleigh and Mie scattering…
Laser science has tackled physical limitations to achieve higher power, faster and smaller light sources. The quest for ultra-compact laser that can directly generate coherent optical fields at the nano-scale, far beyond the diffraction…
Optical circuits and light sources, such as lasers, undergo continuous miniaturization. In its extreme, nanolasers might be comprised of only a few molecules confined in plasmonic nanoresonators. Few-emitter lasers promise low energy…
Due to the absence of labels and fast analyses, optical biosensors promise major advances in biomedical diagnostics, security, environmental and food safety applications. However, sensitivity of the most advanced plasmonic biosensor…
Recently, nanomaterials are arousing increasing interest and a wide variety of opto-electronic devices have been developed, such as light-emitting diodes, solar cells, and photodetectors. However, the study of the light emission properties…
Single molecule detection provides detailed information about molecular structures and functions, but it generally requires the presence of a fluorescent marker which can interfere with the activity of the target molecule or complicate the…
Enhanced manipulation and analysis of bio-particles using light confined in nano-scale dielectric structures has proceeded apace in the last several years. Small mode volumes, along with the lack of a need for bulky optical elements give…
Ultrasound sensors have wide applications across science and technology. However, improved sensitivity is required for both miniaturisation and increased spatial resolution. Here, we introduce cavity optomechanical ultrasound sensing, where…
We propose a protocol to measure impulses beyond the standard quantum limit. The protocol reduces noise in all three spatial dimensions and consists of squeezing a mechanical system's state via a series of jumps in the frequency of the…
Optical fibers are crucial for guiding light in various sensing applications. Especially for quantum sensors such as the nitrogen-vacancy (NV) center in diamond, they enable light control and device miniaturization. However, fluorescence…
Absorption spectroscopy is routinely used to characterise chemical and biological samples. For the state-of-the-art in absorption spectroscopy, precision is theoretically limited by shot-noise due to the fundamental Poisson-distribution of…
We propose a method of spatial resolution enhancement in metrology (thermometry, magnetometry, pH estimation, and similar methods) with blinking fluorescent nanosensors by combining sensing with super-resolution optical fluctuation imaging…
Low dimensional nano-systems are promising candidates for manipulating, controlling and capturing photons with large sensitivities and low-noise. If quantum engineered to tailor the energy of the localized electrons across the desired…
Phase transitions can dramatically alter system dynamics, unlocking new behavior and improving performance. Exceptional points (EPs), where the eigenvalues and corresponding eigenvectors of a coupled linear system coalesce, are particularly…
Measuring the electrophoretic mobility of molecules is a powerful experimental approach for investigating biomolecular processes. A frequent challenge in the context of single-particle measurements is throughput, limiting the obtainable…
The interaction between light and matter can be enhanced by spatially concentrating the light field to boost the photon energy density and increasing the photon dwell time to prolong energy transfer between light and matter. Traditionally,…
Nanophotonic platforms in theory uniquely enable < femtomoles of chiral biological and pharmaceutical molecules to be detected, through the highly localised changes in the chiral asymmetries of the near-fields that they induce. However,…