Related papers: Evanescent single-molecule biosensing with quantum…
The possibility of using weak optical signals to perform sensing of delicate samples constitutes one of the main goals of quantum photonic sensing. Furthermore, the nanoscale confinement of electromagnetic near fields in photonic platforms…
Photon counting is a cornerstone of quantum optics. Here, we demonstrate precisely counting from 0 to over 9000 photons, beating the Poisson noise limit by at least $4.1~\mathrm{dB}$ across this range. We achieve sub-single-photon precision…
Individual, luminescent point defects in solids so called color centers are atomic-sized quantum systems enabling sensing and imaging with nanoscale spatial resolution. In this overview, we introduce nanoscale sensing based on individual…
Here we demonstrate a new concept for designing an ultra-sensitive deformed cavity biosensor. Owning to the breaking of rotational symmetry, the field distribution is not uniform along the cavity boundary and results in the dependence of…
The ultimate sensitivity of optical measurements is a key element of many recent works. Classically, it is mainly limited by the shot noise limit. However, a measurement setup that incorporates quantum mechanical principles can surpass the…
A conformal coating technique with nanocarbon was developed to enhance the surface properties of alumina nanoparticles for bio-applications. The ultra-thin carbon layer induces new surface properties such as water dispersion,…
The quantum statistical fluctuations of the electromagnetic field establish a limit, known as the shot-noise limit, on the sensitivity of optical measurements performed with classical technologies. However, quantum technologies are not…
Interferometric-based microscopies stand as powerful label-free approaches for monitoring and characterising chemical reactions and heterogeneous nanoparticle systems in real time with single particle sensitivity. Nevertheless, coherent…
Infrared spectroscopy is the technique of choice for chemical identification of biomolecules through their vibrational fingerprints. However, infrared light interacts poorly with nanometric size molecules. Here, we exploit the unique…
Quantum metrology provides a route to overcome practical limits in sensing devices. It holds particular relevance to biology, where sensitivity and resolution constraints restrict applications both in fundamental biophysics and in medicine.…
Engineering the electromagnetic environment of a nanoscale light emitter by a photonic cavity can significantly enhance its spontaneous emission rate through cavity quantum electrodynamics in the Purcell regime. This effect can greatly…
Establishing a highly efficient photon-emitter interface where the intrinsic linewidth broadening is limited solely by spontaneous emission is a key step in quantum optics. It opens a pathway to coherent light-matter interaction for, e.g.,…
Efficient capture and detection of minute amount of deoxyribonucleic acid (DNA) molecules are pivotal for an array of modern gene technologies which are widely utilized in medical, forensic and defense applications, including DNA…
Quantum metrology enables some of the most precise measurements. In the life sciences, diamond-based quantum sensing has enabled a new class of biophysical sensors and diagnostic devices that are being investigated as a platform for cancer…
Quantum measurements of mechanical systems can produce optical squeezing via ponderomotive forces. Its observation requires high environmental isolation and efficient detection, typically achieved by using optical cavities and cryogenic…
One of the most important processes in the fight against current and future pandemics is the rapid diagnosis and initiation of treatment of viruses in humans. In these times, the development of high-sensitivity tests and diagnostic kits is…
Nanoparticle-based fluorescent sensors have emerged as a competitive alternative to small molecule sensors, due to their excellent fluorescence-based sensing capabilities. The tailorability of design, architecture, and photophysical…
Ultrasensitive optical detection of nanometer-scaled particles is highly desirable for applications in early-stage diagnosis of human diseases, environmental monitoring, and homeland security, but remains extremely difficult due to ultralow…
Superconducting nanowire single-photon detectors are an enabling technology for modern quantum information science and are gaining attractiveness for the most demanding photon counting tasks in other fields. Embedding such detectors in…
The detection of single molecules has facilitated many advances in life- and material-sciences. Commonly, it founds on the fluorescence detection of single molecules, which are for example attached to the structures under study. For…