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Summary: The Systems Biology Markup Language (SBML) is an extensible standard format for exchanging biochemical models. One of the extensions for SBML is the SBML Layout and Render package. This allows modelers to describe a biochemical…

Quantitative Methods · Quantitative Biology 2022-11-16 Jin Xu , Jessie Jiang , Herbert M. Sauro

A brief informal overview on the BioPAX and SBML standards for formal presentation of complex biological knowledge.

Data Structures and Algorithms · Computer Science 2011-09-23 Leo Lahti

Background: Systems biology projects and omics technologies have led to a growing number of biochemical pathway reconstructions. However, mathematical models are still most often created de novo, based on reading the literature and…

Advances in bioengineering and biomedicine demand a deep understanding of the dynamic behavior of biological systems, ranging from protein pathways to complex cellular processes. Biological networks like gene regulatory networks and protein…

Biomolecules · Quantitative Biology 2023-10-31 Mayalen Etcheverry , Michael Levin , Clément Moulin-Frier , Pierre-Yves Oudeyer

Biomedical Information Extraction is an exciting field at the crossroads of Natural Language Processing, Biology and Medicine. It encompasses a variety of different tasks that require application of state-of-the-art NLP techniques, such as…

Computation and Language · Computer Science 2017-05-17 Surag Nair

Many theoretical works and tools on epidemiological field reflect the emphasis on decision-making Tools by both public health and the scientific community, which continues to increase. Indeed, in the epidemiological field, modeling tools…

Computational Engineering, Finance, and Science · Computer Science 2013-11-18 Dalila Hamami , Baghdad Atmani

The design of complex engineering systems is an often long and articulated process that highly relies on engineers' expertise and professional judgment. As such, the typical pitfalls of activities involving the human factor often manifest…

Computation and Language · Computer Science 2022-11-22 Shaohong Zhong , Andrea Scarinci , Alice Cicirello

This paper presents libRoadRunner, an extensible, high-performance, cross-platform, open-source software library for the simulation and analysis of models \ expressed using Systems Biology Markup Language (SBML). SBML is the most widely…

Subcellular Processes · Quantitative Biology 2015-03-04 Endre T. Somogyi , Jean-Marie Bouteiller , James A. Glazier , Matthias König , Kyle Medley , Maciej H. Swat , Herbert M. Sauro

In modern electronic medical records (EMR) much of the clinically important data - signs and symptoms, symptom severity, disease status, etc. - are not provided in structured data fields, but rather are encoded in clinician generated…

Computation and Language · Computer Science 2014-08-10 Son Doan , Mike Conway , Tu Minh Phuong , Lucila Ohno-Machado

Multi-class event streams arise in numerous real-world applications, where uncovering structured, interpretable inter-event relationships, together with accurate prediction, remains a central challenge. Existing neural point process models…

Machine Learning · Computer Science 2026-05-21 Zhitong Xu , Qiwei Yuan , Yinghao Chen , Shandian Zhe , Bin Shen

By adequate employing of complex event processing (CEP), valuable information can be extracted from the underlying complex system and used in controlling and decision situations. An example application area is management of IT systems for…

Software Engineering · Computer Science 2012-08-02 Istvan David

Natural Language Processing (NLP) systems often make use of machine learning techniques that are unfamiliar to end-users who are interested in analyzing clinical records. Although NLP has been widely used in extracting information from…

Human-Computer Interaction · Computer Science 2017-07-10 Gaurav Trivedi , Phuong Pham , Wendy Chapman , Rebecca Hwa , Janyce Wiebe , Harry Hochheiser

Structured Natural Language Processing (XNLP) is an important subset of NLP that entails understanding the underlying semantic or syntactic structure of texts, which serves as a foundational component for many downstream applications.…

Computation and Language · Computer Science 2024-06-24 Hao Fei , Meishan Zhang , Min Zhang , Tat-Seng Chua

Event schemas are structured knowledge sources defining typical real-world scenarios (e.g., going to an airport). We present a framework for efficient human-in-the-loop construction of a schema library, based on a novel script induction…

Computation and Language · Computer Science 2022-05-24 Noah Weber , Anton Belyy , Nils Holzenberger , Rachel Rudinger , Benjamin Van Durme

We introduce a natural language interface for building stochastic pi calculus models of biological systems. In this language, complex constructs describing biochemical events are built from basic primitives of association, dissociation and…

Programming Languages · Computer Science 2009-11-13 Ozan Kahramanoğullari , Luca Cardelli , Emmanuelle Caron

We introduce the concept of structured synthesis for Markov decision processes where the structure is induced from finitely many pre-specified options for a system configuration. The resulting synthesis problem is in general a nonlinear…

Software Engineering · Computer Science 2018-07-18 Nils Jansen , Laura Humphrey , Jana Tumova , Ufuk Topcu

Natural Language Processing (NLP) has transformed various fields beyond linguistics by applying techniques originally developed for human language to the analysis of biological sequences. This review explores the application of NLP methods…

Computation and Language · Computer Science 2025-06-04 Ella Rannon , David Burstein

This paper contributes to speeding up the design and deployment of engineering dynamical systems by proposing a strategy for exploiting domain and expert knowledge for the automated generation of a dynamical system computational model…

Computation and Language · Computer Science 2026-04-23 Matthew Anderson Hendricks , Alice Cicirello

This literature review studies the field of automated process extraction, i.e., transforming textual descriptions into structured processes using Natural Language Processing (NLP). We found that Machine Learning (ML) / Deep Learning (DL)…

Computation and Language · Computer Science 2024-09-24 William Van Woensel , Soroor Motie

Motivation: Computational models in biology can increase our understanding of biological systems, be used to answer research questions, and make predictions. Accessibility and reusability of computational models is limited and often…

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