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Systems biology models are useful models of complex biological systems that may require a large amount of experimental data to fit each model's parameters or to approximate a likelihood function. These models range from a few to thousands…

Quantitative Methods · Quantitative Biology 2024-07-12 Vincent D. Zaballa , Elliot E. Hui

Temporal point processes (TPPs) are widely used to model the timing and occurrence of events in domains such as social networks, transportation systems, and e-commerce. In this paper, we introduce TPP-LLM, a novel framework that integrates…

Machine Learning · Computer Science 2025-06-11 Zefang Liu , Yinzhu Quan

Nowadays, multiscale modelling is recognized as the most suitable way to study biological processes. Indeed, almost every phenomenon in nature exhibits a multiscale behaviour, i.e., it is the outcome of interactions that occur at different…

Formal Languages and Automata Theory · Computer Science 2011-08-18 Federico Buti , Massimo Callisto De Donato , Flavio Corradini , Emanuela Merelli , Luca Tesei

We propose a bias-aware methodology to engage with power relations in natural language processing (NLP) research. NLP research rarely engages with bias in social contexts, limiting its ability to mitigate bias. While researchers have…

Computation and Language · Computer Science 2020-11-12 Lucy Havens , Melissa Terras , Benjamin Bach , Beatrice Alex

Our research explores the use of natural language processing (NLP) methods to automatically classify entities for the purpose of knowledge graph population and integration with food system ontologies. We have created NLP models that can…

We describe our ongoing research that centres on the application of natural language processing (NLP) to software engineering and systems development activities. In particular, this paper addresses the use of NLP in the requirements…

Computation and Language · Computer Science 2014-07-24 S. G. Macdonell , K. Min , A. M. Connor

Process modeling is usually done using imperative modeling languages like BPMN or EPCs. In order to cope with the complexity of human-centric and flexible business processes several declarative process modeling languages (DPMLs) have been…

Software Engineering · Computer Science 2016-03-22 Lars Ackermann , Stefan Schönig , Stefan Jablonski

This paper introduces a new approach to hybrid traffic modeling, along with its implementation in software. The software allows modelers to assign traffic models to individual links in a network. Each model implements a series of methods,…

Mathematical Software · Computer Science 2019-08-13 Gabriel Gomes

The vast majority of biochemical systems involve the exchange of information between different compartments, either in the form of transportation or via the intervention of membrane proteins which are able to transmit stimuli between…

Computational Engineering, Finance, and Science · Computer Science 2009-11-30 Federica Ciocchetta , Adam Duguid , Maria Luisa Guerriero

There is a small but growing body of research on statistical scripts, models of event sequences that allow probabilistic inference of implicit events from documents. These systems operate on structured verb-argument events produced by an…

Computation and Language · Computer Science 2016-06-09 Karl Pichotta , Raymond J. Mooney

In the field of brain-machine interfaces, biohybrids offer an interesting new perspective, as in them, the technological side acts like a closed-loop extension or real counterpart of biological tissue, instead of the usual open loop…

Neurons and Cognition · Quantitative Biology 2025-01-17 Christian Georg Mayr , Richard Miru George , Mattia Tambaro , Giacomo Indiveri

In Business Process Management (BPM), effectively comprehending process models is crucial yet poses significant challenges, particularly as organizations scale and processes become more complex. This paper introduces a novel framework…

We introduce novel mathematical models and algorithms to generate (shortest or k different) explanations for biomedical queries, using answer set programming. We implement these algorithms and integrate them in BIOQUERY-ASP. We illustrate…

Artificial Intelligence · Computer Science 2020-02-19 Esra Erdem , Umut Oztok

Recently, symbolic computation and computer algebra systems have been successfully applied in systems biology, especially in chemical reaction network theory. One advantage of symbolic computation is its potential for qualitative answers to…

Molecular Networks · Quantitative Biology 2022-01-25 Christoph Lüders , Thomas Sturm , Ovidiu Radulescu

We describe a binding schema markup language (BSML) for describing data interchange between scientific codes. Such a facility is an important constituent of scientific problem solving environments (PSEs). BSML is designed to integrate with…

Computational Engineering, Finance, and Science · Computer Science 2007-05-23 Alex Verstak , Naren Ramakrishnan , Layne T. Watson , Jian He , Clifford A. Shaffer , Kyung Kyoon Bae , Jing Jiang , William H. Tranter , Theodore S. Rappaport

Natural Language Processing (NLP) is a key technique for developing Medical Artificial Intelligence (AI) systems that leverage Electronic Health Record (EHR) data to build diagnostic and prognostic models. NLP enables the conversion of…

Path planners that can interpret free-form natural language instructions hold promise to automate a wide range of robotics applications. These planners simplify user interactions and enable intuitive control over complex semi-autonomous…

Artificial Intelligence · Computer Science 2024-09-17 William English , Dominic Simon , Sumit Jha , Rickard Ewetz

Event Extraction (EE), aiming to identify and classify event triggers and arguments from event mentions, has benefited from pre-trained language models (PLMs). However, existing PLM-based methods ignore the information of trigger/argument…

Computation and Language · Computer Science 2023-05-22 Xingyu Bai , Taiqiang Wu , Han Guo , Zhe Zhao , Xuefeng Yang , Jiayi Li , Weijie Liu , Qi Ju , Weigang Guo , Yujiu Yang

Many NLP applications require models to be interpretable. However, many successful neural architectures, including transformers, still lack effective interpretation methods. A possible solution could rely on building explanations from…

Computation and Language · Computer Science 2024-04-04 Federico Ruggeri , Marco Lippi , Paolo Torroni

In this paper we propose a methodology for deriving a model of a complex system by exploiting the information extracted from Topological Data Analysis. Central to our approach is the S[B] paradigm in which a complex system is represented by…

Emerging Technologies · Computer Science 2015-05-26 Emanuela Merelli , Matteo Rucco , Peter Sloot , Luca Tesei