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In this paper we consider the problem of approximating Euclidean distances by the infinite integer grid graph. Although the topology of the graph is fixed, we have control over the edge-weight assignment $w:E\to \mathbb{R}_{\ge 0}$, and…

Computational Geometry · Computer Science 2025-11-25 Zixi Cai , Kuowen Chen , Shengquan Du , Arnold Filtser , Seth Pettie , Daniel Skora

Animals build Bayesian 3D models of their surroundings, to control their movements. There is strong selection pressure to make these models as precise as possible, given their sense data. A previous paper has described how a precise 3D…

Neurons and Cognition · Quantitative Biology 2024-05-17 Robert Worden

Distances are pervasive in machine learning. They serve as similarity measures, loss functions, and learning targets; it is said that a good distance measure solves a task. When defining distances, the triangle inequality has proven to be a…

Machine Learning · Computer Science 2020-07-08 Silviu Pitis , Harris Chan , Kiarash Jamali , Jimmy Ba

Hippocampal neurons track positions of self, others, and gaze direction. However, it is unclear how their respective neural codes differ enough to avoid confusion while allowing for abstraction. We recorded from populations of hippocampal…

Grid cells in the medial entorhinal cortex (MEC) respond when an animal occupies a periodic lattice of "grid fields" in the environment. The grids are organized in modules with spatial periods, or scales, clustered around discrete values…

Neurons and Cognition · Quantitative Biology 2019-03-13 Louis Kang , Vijay Balasubramanian

We advertise the use of tetrahedral grids constructed via the longest edge bisection algorithm for rendering volumetric data with path tracing. The key benefits of such grids is two-fold. First, they provide a highly adaptive…

Graphics · Computer Science 2025-06-16 Anis Benyoub , Jonathan Dupuy

Our knowledge of the sensory world is encoded by neurons in sequences of discrete, identical pulses termed action potentials or spikes. There is persistent controversy about the extent to which the precise timing of these spikes is relevant…

Neurons and Cognition · Quantitative Biology 2007-05-23 Ilya Nemenman , Geoffrey D. Lewen , William Bialek , Rob R. de Ruyter van Steveninck

In the mammalian brain, many neuronal ensembles are involved in representing spatial structure of the environment. In particular, there exist cells that encode the animal's location and cells that encode head direction. A number of studies…

Neurons and Cognition · Quantitative Biology 2021-08-10 Y. Dabaghian

Neurons in the brain are often finely tuned for specific task variables. Moreover, such disentangled representations are highly sought after in machine learning. Here we mathematically prove that simple biological constraints on neurons,…

Neurons and Cognition · Quantitative Biology 2023-04-04 James C. R. Whittington , Will Dorrell , Surya Ganguli , Timothy E. J. Behrens

Sensory systems across all modalities and species exhibit adaptation to continuously changing input statistics. Individual neurons have been shown to modulate their response gains so as to maximize information transmission in different…

Neurons and Cognition · Quantitative Biology 2023-06-01 Lyndon R. Duong , Colin Bredenberg , David J. Heeger , Eero P. Simoncelli

Recent advances in neuroscientific experimental techniques have enabled us to simultaneously record the activity of thousands of neurons across multiple brain regions. This has led to a growing need for computational tools capable of…

We develop a phenomenological coarse--graining procedure for activity in a large network of neurons, and apply this to recordings from a population of 1000+ cells in the hippocampus. Distributions of coarse--grained variables seem to…

Neurons and Cognition · Quantitative Biology 2019-10-30 Leenoy Meshulam , Jeffrey L. Gauthier , Carlos D. Brody , David W. Tank , William Bialek

A detailed environment perception is a crucial component of automated vehicles. However, to deal with the amount of perceived information, we also require segmentation strategies. Based on a grid map environment representation, well-suited…

Computer Vision and Pattern Recognition · Computer Science 2018-12-06 Sascha Wirges , Tom Fischer , Jesus Balado Frias , Christoph Stiller

Over the brief time intervals available for processing retinal output, roughly 50 to 300 msec, the number of extra spikes generated by individual ganglion cells can be quite variable. Here, computer-generated spike trains were used to…

Neurons and Cognition · Quantitative Biology 2007-09-14 Garrett T. Kenyon

Motile biological cells in tissue often display the phenomenon of durotaxis, i.e. they tend to move towards stiffer parts of substrate tissue. The mechanism for this behavior is not completely understood. We consider simplified models for…

Biological Physics · Physics 2019-01-03 Charles R. Doering , Xiaoming Mao , Leonard M. Sander

In both neuroscience and artificial intelligence, popular functional frameworks and neural network formulations operate by making use of extrinsic error measurements and global learning algorithms. Through a set of conjectures based on…

Neurons and Cognition · Quantitative Biology 2026-02-18 Linus Mårtensson , Jonas M. D. Enander , Udaya B. Rongala , Henrik Jörntell

The hippocampus supports spatial navigation by encoding cognitive maps through collective place cell activity. We model the place cell population as non-negative spatial embeddings derived from the spectral decomposition of multi-step…

Neurons and Cognition · Quantitative Biology 2025-10-28 Minglu Zhao , Dehong Xu , Deqian Kong , Wen-Hao Zhang , Ying Nian Wu

Neurons in the visual cortex respond best to rod-like stimuli of given orientation. While the preferred orientation varies continuously across most of the cortex, there are prominent pinwheel centers around which all orientations a re…

Statistical Mechanics · Physics 2009-11-10 Ha Youn Lee , Mehdi Yahyanejad , Mehran Kardar

Brain research has been driven by enquiry for principles of brain structure organization and its control mechanisms. The neuronal wiring map of C. elegans, the only complete connectome available till date, presents an incredible opportunity…

Neurons and Cognition · Quantitative Biology 2016-11-28 Rahul Badhwar , Ganesh Bagler

The transfer of mechanical signals through cells is a complex phenomenon. To uncover a new mechanotransduction pathway, we study the frequency-dependent transport of mechanical stimuli by single microtubules and small networks in a…

Biological Physics · Physics 2017-05-03 M. D. Koch , N. Schneider , P. Nick , A. Rohrbach
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