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Related papers: Modeling delayed processes in biological systems

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The characteristic equation for a linear delay differential equation (DDE) has countably infinite roots on the complex plane. This paper considers linear DDEs that are on the verge of instability, i.e. a pair of roots of the characteristic…

Probability · Mathematics 2016-06-08 Nishanth Lingala , N. Sri Namachchivaya

This paper focuses on time-varying delayed stochastic differential systems with stochastically switching parameters formulated by a unified switching behavior combining a discrete adapted process and a Cox process. Unlike prior studies…

Dynamical Systems · Mathematics 2024-01-30 Xinyu Wu , Zidong Wang , Wenlian Lu

Delays are an important phenomenon arising in a wide variety of real world systems. They occur in biological models because of diffusion effects or as simplifying modeling elements. We propose here to consider delayed stochastic reaction…

Optimization and Control · Mathematics 2020-04-27 Corentin Briat , Mustafa Khammash

Stochastic differential equations (SDEs) are of utmost importance in various scientific and industrial areas. They are the natural description of dynamical processes whose precise equations of motion are either not known or too expensive to…

Methodology · Statistics 2017-11-08 Philipp Frank , Theo Steininger , Torsten A. Enßlin

Networks of globally coupled, noise activated, bistable elements with connection time delays are considered. The dynamics of these systems is studied numerically using a Langevin description and analytically using (1) a Gaussian…

Statistical Mechanics · Physics 2009-11-11 Daniel Huber , Lev Tsimring

Real-world systems can be strongly influenced by time delays occurring in self-coupling interactions, due to unavoidable finite signal propagation velocities. When the delays become significantly long, complicated high-dimensional phenomena…

Chaotic Dynamics · Physics 2022-06-08 Serhiy Yanchuk , Giovanni Giacomelli

We study abstract linear and nonlinear evolutionary systems with single or multiple delay feedbacks, illustrated by several concrete examples. In particular, we assume that the operator associated with the undelayed part of the system…

Analysis of PDEs · Mathematics 2019-02-21 Vilmos Komornik , Cristina Pignotti

We consider a model for substrate-depletion oscillations in genetic systems, based on a stochastic differential equation with a slowly evolving external signal. We show the existence of critical transitions in the system. We apply two…

Chaotic Dynamics · Physics 2014-03-13 Jesse Berwald , Marian Gidea

Simulation of stochastic spatially-extended systems is a challenging problem. The fundamental quantities in these models are individual entities such as molecules, cells, or animals, which move and react in a random manner. In big systems,…

Quantitative Methods · Quantitative Biology 2024-09-24 Tomás Alarcón , Natalia Briñas-Pascual , Juan Calvo , Pilar Guerrero , Daria Stepanova

Modern agile software projects are subject to constant change, making it essential to re-asses overall delay risk throughout the project life cycle. Existing effort estimation models are static and not able to incorporate changes occurring…

Software Engineering · Computer Science 2023-10-04 Elvan Kula , Eric Greuter , Arie van Deursen , Georgios Gousios

Time series with non-uniform intervals occur in many applications, and are difficult to model using standard recurrent neural networks (RNNs). We generalize RNNs to have continuous-time hidden dynamics defined by ordinary differential…

Machine Learning · Computer Science 2019-07-10 Yulia Rubanova , Ricky T. Q. Chen , David Duvenaud

Although the theory of density evolution in maps and ordinary differential equations is well developed, the situation is far from satisfactory in continuous time systems with delay. This paper reviews some of the work that has been done…

Dynamical Systems · Mathematics 2022-11-07 Michael C. Mackey , Marta Tyran-Kamińska

Anticipated synchronisation occurs when a driven dynamical system synchronises with the future state of the driver system to which it is unidirectionally coupled. Previous theoretical and experimental studies have focused on setups with a…

Chaotic Dynamics · Physics 2026-03-04 David Ortiz del Campo , Tobias Galla , Raúl Toral

Time-delay systems are, in many ways, a natural set of dynamical systems for natural scientists to study because they form an interface between abstract mathematics and data. However, they are complicated because past states must be…

Chaotic Dynamics · Physics 2007-10-16 D. J. Albers , Fatihcan M. Atay

In scalable machine learning systems, model training is often parallelized over multiple nodes that run without tight synchronization. Most analysis results for the related asynchronous algorithms use an upper bound on the information…

Machine Learning · Computer Science 2022-04-12 Xuyang Wu , Sindri Magnusson , Hamid Reza Feyzmahdavian , Mikael Johansson

Discrete-event (DE) systems are concurrent programs where components communicate via tagged events, where tags are drawn from a totally ordered set. Reactors are an emerging model of computation based on DE and realized in the open-source…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-05-21 Peter Donovan , Erling Jellum , Byeonggil Jun , Hokeun Kim , Edward A. Lee , Shaokai Lin , Marten Lohstroh , Anirudh Rengarajan

The dynamics of systems biological processes are usually modeled by a system of ordinary differential equations (ODEs) with many unknown parameters that need to be inferred from noisy and sparse measurements. Here, we introduce…

Quantitative Methods · Quantitative Biology 2022-02-04 Mitchell Daneker , Zhen Zhang , George Em Karniadakis , Lu Lu

The paper discusses linear fractional representations of parameter-dependent nonlinear systems with dynamics defined by real rational nonlinearities and a finite set of point delays. The global asymptotic stability is investigated via…

Dynamical Systems · Mathematics 2008-03-27 M. De la Sen

Biological systems are often modeled as a system of ordinary differential equations (ODEs) with time-invariant parameters. However, cell signaling events or pharmacological interventions may alter the cellular state and induce multi-mode…

Quantitative Methods · Quantitative Biology 2020-04-28 Bing Liu

Declarative approaches to process modeling are regarded as well suited for highly volatile environments as they provide a high degree of flexibility. However, problems in understanding and maintaining declarative business process models…

Software Engineering · Computer Science 2015-11-12 Cornelia Haisjackl , Stefan Zugal , Pnina Soffer , Irit Hadar , Manfred Reichert , Jakob Pinggera , Barbara Weber